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tim.hodson Mon, 03/17/2025 - 14:56 March 17, 2025 Being born with a heart defect may be associated with an increased cancer risk for babies and their moms, according to new research published today in the American Heart Associations flagship journal Circulation. are forms of congenital heart defects (CHD). Lopez, M.D.,
Research Highlights: Newborns with congenital heart defects may have a higher risk of developing childhood cancer compared to children born without a heart abnormality. Congenital heart defects in newborns may also signal an elevated cancer risk for.
The field of cardio-oncology has expanded over the past 2 decades to address the ever-increasing issues related to cardiovascular disease in patients with cancer and survivors.
Research Highlights: Increased physical activity including taking more daily steps was linked to a lower risk of death from cardiovascular disease among postmenopausal women with a history of cancer. The study found that engaging in one hour per day.
Blocking a protein known as CDK7 could prevent heart damage associated with a commonly used cancer chemotherapy medication, according to a new study. Importantly, the researchers also found that inhibiting CDK7 could help enhance the medication's cancer-killing capability.
Research shows that a common type of diabetes medication could help cancer patients make a better long-term recovery. Many cancer patients go on to develop heart failure -- because of the cancer itself and also due to chemotherapy.
Researchers at Tel Aviv University (TAU) and the Leviev Cardiothoracic and Vascular Center at the Sheba Medical Center have found a mechanism responsible for increasing the risk of developing cancer among patients with heart disease: Small extracellular bubbles, or vesicles (sEVs), secreted from the sick heart to heal itself, are released into the (..)
(MedPage Today) -- A Scandinavian cohort study suggested a popular class of diabetes drug did not put patients at an elevated risk for thyroid cancer, a longtime lingering concern with this drug class. Compared with DPP-4 inhibitors, patients.
Biomedical engineers at Duke University have demonstrated that one of the most dangerous mutations found in skin cancers might moonlight as a pathway to mending a broken heart.
(MedPage Today) -- Long-term cancer survivors tended to live longer if they consumed a Mediterranean diet, analysis of an Italian cohort study found. With a follow-up of almost 13 years, survivors with high adherence to the diet had a 32% lower.
(MedPage Today) -- Survivors of childhood cancer were much more likely to develop an aging-associated health condition before the age of 65, with earlier onset, compared with the general population, according to a modeling study. While 20% of.
Getty Images milla1cf Wed, 06/19/2024 - 20:54 June 19, 2024 — Modern therapies have extended the lives of many cancer patients; however, survivors often live with chronic health conditions, including cardiovascular disease. They found that exposure to PM2.5,
Functionally, this interaction heightens HRR, leading to a decrease in residual DNA damage in colon cancer cells. This contributes to chemoresistance in colon cancer cells against cisplatin, camptothecin, and oxaliplatin, eventually promoting tumorigenesis in preclinical colon cancer mouse models.
A paucity of chemotherapeutic options for metastatic brain cancer limits patient survival and portends poor clinical outcomes. Metixene, an antiparkinsonian drug, was identified as a top therapeutic agent that was capable of decreasing cellular viability and inducing cell death across different metastatic breast cancer subtypes.
The approval is based on findings from BLUE-C, where Cologuard Plus demonstrated sensitivities of 95% for colorectal cancer and 43% for advanced precancerous lesions at 94% specificity.
Nature Reviews Cardiology, Published online: 10 April 2024; doi:10.1038/s41569-024-01017-x Patients with cardiovascular disease (CVD) have an increased risk of cancer, and patients with cancer have an increased risk of CVD.
(MedPage Today) -- GLP-1 receptor agonists lowered the risk of several obesity-associated cancers, a retrospective analysis of electronic health records suggested. Compared with insulin, GLP-1s were associated with a lower risk for developing.
(MedPage Today) -- A 4-month-old with congenital hyperinsulinism responded well to off-label treatment with a breast cancer drug, researchers reported. A newborn presented with severe congenital hyperinsulinism due to homozygous deletion of the.
(MedPage Today) -- Recent skin cancer risk stratification guidelines did not improve rates of timely dermatologic follow-up visits among solid organ transplant recipients, according to an analysis of claims data. The rate of post-transplant dermatology.
New evidence shows that extended estrogen suppression treatment using aromatase inhibitors for hormone receptor-positive postmenopausal breast cancer is safe; it does not increase the risk of coronary artery calcification, a sign of active coronary atherosclerosis, as some prior studies had indicated.
(MedPage Today) -- Men treated with androgen deprivation therapy (ADT) for prostate cancer had a significantly higher risk of dementia and other neurocognitive disorders, according to a meta-analysis of more than 2.5 million patients. The magnitude.
Researchers from Brigham and Women's Hospital have used artificial intelligence tools to accelerate the understanding of the risk of specific cardiac arrhythmias when various parts of the heart are exposed to different thresholds of radiation as part of a treatment plan for lung cancer.
The Mediterranean diet is a powerful ally for health even after a cancer diagnosis. This is the key result of an Italian study carried out as part of the UMBERTO Project, conducted by the Joint Research Platform Umberto Veronesi Foundation—Department of Epidemiology and Prevention of the I.R.C.C.S.
Cancer patients with behavioral health disorders, such as substance abuse, eating disorders, and sleep disorders have a 7.76% increase in health care costs, a new study found.
(MedPage Today) -- The addition of androgen receptor signaling inhibitors (ARSIs) alongside standard androgen deprivation therapy (ADT) in advanced prostate cancer was associated with a significantly increased risk of adverse heart events, a systematic.
Salivary gland dysfunction is a common side effect of cancer treatments. Consequently, changes in salivary function can profoundly impair quality of life for cancer patients. Current and emerging approaches to treat cancer therapy–induced dry mouth are presented using radiation-induced salivary dysfunction as a model.
Recently, sarcopenia has been linked to unfavorable outcomes in various surgical procedures, including lung cancer surgery. This study aimed to investigate the impact of respiratory sarcopenia (RS) on postoper.
Jude LIFE) have revealed that two common biomarkers of cardiac function and damage could better predict cardiomyopathy within five years than routine clinical evaluations in high-risk, asymptomatic childhood cancer survivors.
(MedPage Today) -- More thyroid cancers were detected soon after starting a GLP-1 receptor agonist than other diabetes drugs, a secondary analysis of a target trial emulation of a comparative effectiveness study found. Of over 350,000 adults with.
Cell lineage plasticity is one of the major causes for the failure of targeted therapies in various cancers. However, the driver and actionable drug targets in promoting cancer cell lineage plasticity are scarcely identified.
A cancer therapy that prompts the body's immune defenses against viruses and bacteria to attack tumors can make patients more vulnerable to heart attack and stroke. A possible explanation for this side effect is that the treatment interferes with immune regulation in the heart's largest blood vessels, a new study suggests.
Researchers have found that cells inside clogged arteries have cancer-like properties that aggravate atherosclerosis, and anticancer drugs could be a new treatment.
(MedPage Today) -- Pharmacovigilance is needed to identify, monitor, and prevent cardiovascular adverse events (CV-AEs) associated with new agents for breast cancer and to reduce the risk of cardiotoxicity for the growing number of survivors, according.
GLP-1 RA initiation boosted new thyroid cancer diagnoses, compared with other anti-diabetic drugs, but enhanced early detection may have played a role.
Background Cancer survivors are at increased risk of heart failure (HF). While cardiotoxicity is commonly sought at the time of cancer chemotherapy, HF develops as a result of multiple ‘hits’ over time, and there is limited evidence regarding the frequency and causes of HF during survivorship. compared with 1.7%
Objectives The clinical outcomes of transcatheter aortic valve replacement (TAVR) in patients with aortic stenosis (AS) and concomitant active cancer remain insufficiently explored. This study aimed to assess the midterm outcomes of TAVR in patients diagnosed with AS and active cancer. vs 74.7%, p=0.50).
Metastasized colorectal cancer (CRC) is associated with a poor prognosis and rapid disease progression. Besides hepatic metastasis, peritoneal carcinomatosis is the major cause of death in Union for International Cancer Control (UICC) stage IV CRC patients.
A common type of diabetes medication could help cancer patients make a better long-term recovery, according to new research from the University of East Anglia.
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