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Evidence-Based Application of Natriuretic Peptides in the Evaluation of Chronic Heart Failure With Preserved Ejection Fraction in the Ambulatory Outpatient Setting

Circulation

Current consensus age- and BMI-stratified rule-in thresholds demonstrated only 65% specificity (95% CI, 57%72%). With a BMI 35 kg/m2, lower rule-in thresholds (220 pg/mL) provided good specificity (88% [95% CI, 73%100%]; 93% [95% CI, 81%100%] and 100% in validation cohorts). Circulation, Ahead of Print.

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GLP-1 Receptor Agonists Along With SGLT2 Inhibitors for HFpEF

American College of Cardiology

What is the incremental benefit in patients with heart failure and preserved ejection fraction (HFpEF) of glucagon-like peptide-1 receptor agonists (GLP-1 RA) combined with sodium-glucose cotransporter 2 inhibitors (SGLT2i) in patients with type 2 diabetes mellitus (T2DM) and body mass index (BMI) ≥27?

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University Hospitals Researcher Develops New Score System to Better Screen and Treat HFpEF Heart Failure Patients

DAIC

mtaschetta-millane Wed, 07/31/2024 - 06:00 July 31, 2024 — A novel study co-authored by a heart failure cardiologist at University Hospitals Harrington Heart & Vascular Institute, demonstrates the effectiveness of a newly developed scoring system in identifying patients with Heart Failure with Preserved Ejection Fraction (HFpEF).

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Adiposity, fat-free mass and incident heart failure in 500 000 individuals

Open Heart

Overall, HF risk was more strongly associated with central adiposity (waist circumference (WC) adjusted for body mass index (BMI); HR 1.38, 95% CI 1.32 to 1.45) than general adiposity (BMI adjusted for WC; HR 1.22, 95% CI 1.16 Results Over a median follow-up of 13.8 years, there were 10 455 first-ever incident HF events. to 2.07).

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Obesity in heart failure with preserved ejection fraction: Insights from the REDUCE LAP?HF II trial

European Journal of Heart Failure

Increasing severity of obesity is associated with multiple characteristics that may contribute to the development or worsening of heart failure (HF) with preserved ejection fraction (HFpEF). of patients had BMI ≥30 kg/m 2. Strain measurements in all four chambers were maintained as BMI increased. Overall, 60.9%

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Metabolic dysfunction and incidence of heart failure subtypes among Black individuals: The Jackson Heart Study

European Journal of Heart Failure

We categorized participants based on MetS status and MetS severity scores (based on waist circumference [MetS-Z-WC] and body mass index [MetS-Z-BMI]).

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Hypertensive pregnancy disorder, an under‐recognized women specific risk factor for heart failure?

European Journal of Heart Failure

BMI, body mass index; CV, cardiovascular; CVD, cardiovascular disease; HELLP, haemolysis, elevated liver enzymes, low platelet count. Hypertensive disorders of pregnancy as a risk factor for heart failure.