article thumbnail

Body mass index impacts the lipid-lowing effects of statins in patients with type 2 diabetes

Frontiers in Cardiovascular Medicine

BackgroundIndividuals diagnosed with type 2 diabetes mellitus (T2DM) commonly exhibit elevated lipid levels and an increased body mass index (BMI). The impact of BMI on the efficacy of statins in reducing lipid levels among diabetic patients remains uncertain.

BMI 52
article thumbnail

Is the obesity paradox in outpatients with heart failure reduced ejection fraction real?

Frontiers in Cardiovascular Medicine

The primary objective was to understand the association between body mass index (BMI) and heart failure with reduced ejection fraction (HFREF) of ischemic etiology in outpatients, using mortality as a parameter. 56–70), BMI 18.5–24.9 = 35.1%, 24.9 = 35.1%, 25–29.9 = 37.2%, 30–34.9 = 17.8%, 35–39.9 = 7%; BMI <18.5

article thumbnail

Evidence-Based Application of Natriuretic Peptides in the Evaluation of Chronic Heart Failure With Preserved Ejection Fraction in the Ambulatory Outpatient Setting

Circulation

Current consensus age- and BMI-stratified rule-in thresholds demonstrated only 65% specificity (95% CI, 57%72%). With a BMI 35 kg/m2, lower rule-in thresholds (220 pg/mL) provided good specificity (88% [95% CI, 73%100%]; 93% [95% CI, 81%100%] and 100% in validation cohorts).

article thumbnail

GE Healthcare Launches New Cardiac PET tracer

DAIC

PET is the most effective form of MPI for detecting CAD iii and is recommended for a wide range of patients, including those considered more challenging to diagnose, such as individuals with a BMI greater than 30 or women, especially those with dense breastsi v , over SPECT MPI.

article thumbnail

Association between body mass index and clinical outcomes in patients with acute myocardial infarction and reduced systolic function: Analysis of PARADISE‐MI trial data

European Journal of Heart Failure

Association between body mass index (BMI) and clinical outcomes in PARADISE-MI. ( A ) Histogram for BMI (kg/m 2 ), ( B ) adverse events for BMI subgroups, and spline model curves for ( C ) the primary composite outcome and ( D ) cardiovascular (CV) death by BMI subgroups. 100 patient-years for BMI 40kg/m 2 ).

article thumbnail

Abstract 4142963: Effects of high-intensity inspiratory muscle training as a pre-cardiac rehabilitation intervention on cardiovascular function in patients with heart disease: A pilot study

Circulation

Effect sizes presented based on between groups ANOVA.Results:There were no differences between groups for baseline age, BMI, sex, FMD%, PWV, mMRC, 6MWD and inspiratory muscle strength. An ANOVA was applied using the intention-to-treat analysis. Data are expressed in mean±SD. post = 340.4 ± 36.6 post = 1.6 ± 0.6 post = 68.8 ± 13.6