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It incorporates age, body mass index (BMI), and atrial fibrillation to aid in the diagnosis of HFpEF. The newly developed HFpEF-ABA score model estimates the probability of HFpEF in individual patients based on three simple clinical variables: age, BMI, and atrial fibrillation.
Researchers examined STS registry data on ~109k patients ages 40 to 75 years who received isolated bioprosthetic (94k) or mechanical (15k) AVR over 11 years and found that mechanical valve use decreased by about half (from 20% in 2008 to below 10% in 2019). They also often had lower BMI (31.0 vs 71.8%) or prior PCI (6.7
BMI variability has been associated with increased cardiovascular disease risk in individuals with type 2 diabetes, however comparison between clinical studies and real-world observational evidence has been la.
Obesity, a pervasive health concern, has been identified as a significant risk factor for ATAAD, introducing unique surgical challenges that can influence postoperative outcomes. Based on BMI (WS/T 428-2013), patients were categorized into normal weight, overweight, and obese. Further ROC curve analysis identifies a BMI cutoff of 25.5
BMI) to receive Roux-en-Y gastric bypass and medical therapy or only receive medical therapy, finding that after five years… Far more gastric bypass patients cut their BP medication use by at least 30% (80.7% The GATEWAY trial assigned 100 participants (76% women, 43.8 of them achieved BPs below 130/80 mm Hg (vs.
Understanding the relationship between serum ferritin levels and cardiovascular outcomes in type 2 diabetes is crucial for improving risk stratification and guiding therapeutic interventions aimed at preventin.
In a recent study published in Circulation: Heart Failure , researchers analyzed a large group of individuals with various cardiopulmonary diseases who had undergone right heart catheterization. This research sheds light on the nuanced dynamics between obesity, right ventricular function, and cardiovascular health outcomes.
Associations between metabolic status and metabolic changes with the risk of cardiovascular outcomes have been reported. However, the role of genetic susceptibility underlying these associations remains unexpl.
1 If you want the tl;dr, here it is: After 6 weeks on either a low- or high-carb diet, athletes experienced similar performance outcomes during a time-to-exhaustion test , a result that vindicates low-carb diets once and for all. kg/m² reduction in BMI, and decreased their body fat percentage by 1.9%. kg of body weight, saw a 0.7
Although some studies have examined the association between the triglyceride glucose-body mass index (TyG-BMI) and cardiovascular outcomes in the cardio-renal-metabolic (CRM) background, none have explored its.
In addition, abelacimab consistently reduced bleeding risk in patients 75 years of age and older regardless of renal function, body mass index (BMI), and the use of concomitant antiplatelet therapy. The ARR in patients 75 years of age and older was 6.2% compared to 4.2% in patients less than 75 years. in the low-risk category to 7.1%
The triglyceride glucose-body mass index (TyG-BMI) is recognized as a reliable surrogate for evaluating insulin resistance and an effective predictor of cardiovascular disease. However, the link between TyG-BM.
Background Catheter ablation (CA) for symptomatic atrial fibrillation (AF) offers the best outcomes for patients. Despite the benefits of CA, a significant proportion of patients suffer a recurrence; hence, there is scope to potentially improve outcomes through technical innovations such as ablation index (AI) guidance during AF ablation.
This study is designed to investigate the impact of body mass index (BMI) on the short-term outcomes of patients undergoing off-pump coronary artery bypass graft (OPCAB) surgery.
The primary outcome was to estimate the prevalence of cardiovascular risk factors in patients with hemophilia compared to the general population. Further research is to identify potential ex-specific risk factors that predispose to worse cardiovascular outcomes among patients with hemophilia.
1 Researchers used DNA samples from a total of 144 Japanese men between 65 and 72 years of age to calculate biological age acceleration using several well-established biological clocks: the Horvath clock, the Hannum clock, the PhenoAge clock, the GrimAge clock, and the FitAge clock. A recent study provides us with some novel insight.
Propensity score-matched analysis (PSM) (1:1) was performed with matching for age, gender, race, BMI, hypertension, diabetes mellitus, chronic kidney disease, hemoglobin level, low-density lipid (LDL) level, left ventricular ejection fraction, and various drugs including ACEi, ARBi, ARNI, beta-blockers, and diuretics.
And the more you exercise, the better your outcomes. On the other hand, people who already have CVD or have suffered a CVD event can significantly improve their long-term outcomes by adopting a structured exercise program. Researchers also measured body mass index, waist circumference, blood glucose (HbA1c) and blood lipids.
BMI, body mass index; eGFR, estimated glomerular filtration rate; NYHA, New York Heart Association. Abstract Aims Mineralocorticoid receptor antagonists (MRA) improve outcomes in heart failure with reduced ejection fraction (HFrEF) but are underused.
Real-World Cardiorenal Metabolic Management Cases Case Study 1: The Multidisciplinary Advantage A groundbreaking study compared outcomes between multi-ethnic patients treated by a multidisciplinary team (MDT) and those managed solely by primary care providers (PCPs).
We tested for associations between body mass index (BMI), clinical characteristics, cardiac structural and functional abnormalities, physical limitations, quality of life and outcomes with atrial shunt therapy. of patients had BMI ≥30 kg/m 2. Strain measurements in all four chambers were maintained as BMI increased.
However, there’s not great evidence that multivitamins benefit specific health outcomes. This hypothesis was studied in a randomized controlled trial known as the COcoa Supplement and Multivitamin Outcomes Study or COSMOS. Nutritional insurance? A health- and longevity-boosting powerhouse? Perhaps not.
Notably, MAG showed superior survival for patients with a BMI less than 40, whereas patients with a BMI of 40 or higher had superior survival with SAG. The only patients where single arterial grafting resulted in better survival were severely obese,” said Dr. Sabik.
BMI, body mass index; LVEF, left ventricular ejection fraction; NT-proBNP, N-terminal pro-B-type natriuretic peptide. Aims Chronic obstructive pulmonary disease (COPD) is associated with worse outcomes in heart failure (HF) with mildly reduced or preserved ejection fraction (HFmrEF/HFpEF).
Among participants with baseline body mass index (BMI) above 30 kg/m2, 70.4% Research shows that a 10 point reduction in systolic blood pressure helps lower the risk of coronary heart disease (17%), stroke (27%), heart failure (28%), and all-cause mortality (13%). reduced their weight within 3 months with a mean reduction of 8.8
2, 3] This association is more pronounced for those with class I obesity, which is a body mass index (BMI) between 30-35 kg/m2. These individuals tend to have a better prognosis when compared to both individuals with normal weight (BMI of 18.5 to 25 kg/m2) and underweight (BMI less than 18.5
The researchers examined carotid plaque specimens from 257 patients with asymptomatic carotid artery disease, analyzing their plaque for the presence of 11 MNPs, and tracking the patients’ cardiovascular outcomes over 34 months. age, BMI, comorbidities, prior events), the presence of MNPs in plaque came with a 4.5-times
Association between body mass index (BMI) and clinical outcomes in PARADISE-MI. ( A ) Histogram for BMI (kg/m 2 ), ( B ) adverse events for BMI subgroups, and spline model curves for ( C ) the primary composite outcome and ( D ) cardiovascular (CV) death by BMI subgroups.
Background:Obesity has been associated with an increase in the risk of stroke and poor outcomes. Patients were categorized into a metabolically healthy obese MHO+ve cohort, BMI> 30, and MHO-ve cohort, BMI<30. Stroke, Volume 55, Issue Suppl_1 , Page ATP262-ATP262, February 1, 2024.
Women experienced greater weight loss and the same symptom benefits compared with men, according to research presented today by Dr. Subodh Verma ( St. mg administered to participants once weekly vs placebo on the STEP-HFpEF program’s dual primary and confirmatory secondary, and exploratory outcomes by sex.
BMI, body mass index; CI, confidence interval; LVEF, left ventricular ejection fraction; NT-proBNP, N-terminal pro-B-type natriuretic peptide. ABSTRACT Aim Chronic obstructive pulmonary disease (COPD) is common in heart failure with a mildly reduced or preserved ejection fraction (HFmrEF/HFpEF) and is associated with worse outcomes.
months, participants with baseline body mass index (BMI) above 30 kg/m2 lost 12 pounds, or 5.1% Multiple regression analyses examined the influence of guideline-based, non-pharmacological lifestyle-based digital coaching on outcomes adjusting for confounders. of their body weight. Of 102,475 participants, 49.1% were female.
Notably, women, despite being more susceptible to PH, often experience better survival outcomes than men—a phenomenon possibly linked to the "estrogen paradox." This study leverages the comprehensive UK Biobank to examine the role of sex in influencing these outcomes.
Then identified clusters are predicted and tested in the learning set to evaluate their association with outcomes. Clusters were significantly associated with outcomes in derivation and validation datasets, with Cluster 1 having the highest risk, and Cluster 4 the lowest.
Participating in any resistance training is associated with a 15%–17% lower risk for these outcomes compared to non-participation. Of course, these benefits can also extend to individuals with a BMI in the normal range.
Participating in any resistance training is associated with a 15%–17% lower risk for these outcomes compared to non-participation. Of course, these benefits can also extend to individuals with a BMI in the normal range.
a data analyst at Massachusetts General Hospital in Boston and formerly a researcher at the Center for Tobacco Control Research and Education at the University of California, San Francisco , where she conducted the study as part of her postdoctoral work. Cannabis use could be an important, underappreciated source of heart disease.”
The FDA decision is based on the results of the landmark SELECT phase 3 cardiovascular outcomes trial that examined the effect of adding Wegovy 2.4 1,2 The primary composite outcome occurred in 6.5% 1,2 The primary composite outcome occurred in 6.5% Semaglutide and Cardiovascular Outcomes in Obesity without Diabetes.
Introduction:Atrial fibrillation (AF) is a common cardiac arrhythmia, the risk of cardiovascular adverse outcome rises when it coexists with acute coronary syndrome (ACS) or undergoing percutaneous coronary intervention (PCI).
However, research examining this relationship remains limited.MethodsThis single-center prospective study enrolled 308 STEMI patients. The primary outcome was MACE one-year post-STEMI. The accumulation of epicardial adipose tissue (EAT) may be associated with poorer STEMI prognosis and could serve as a potential prognostic marker.
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