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Patients with lean NAFLD had fewer metabolic comorbidities but maintained similar risk of NASH, cirrhosis, nonliver cancer, and mortality compared to their overweight and obese counterparts.
BMI variability has been associated with increased cardiovascular disease risk in individuals with type 2 diabetes, however comparison between clinical studies and real-world observational evidence has been la.
They also often had lower BMI (31.0 The studys design also wasnt powered to make any certain conclusions due to its reliance on registry data, meaning a randomized head-to-head trial would be needed to confirm these outcomes. Patients receiving bioprosthetic valves tended to be older (65.2 vs 71.8%) or prior PCI (6.7
Obesity, a pervasive health concern, has been identified as a significant risk factor for ATAAD, introducing unique surgical challenges that can influence postoperative outcomes. Based on BMI (WS/T 428-2013), patients were categorized into normal weight, overweight, and obese. Further ROC curve analysis identifies a BMI cutoff of 25.5
Understanding the relationship between serum ferritin levels and cardiovascular outcomes in type 2 diabetes is crucial for improving risk stratification and guiding therapeutic interventions aimed at preventin.
Associations between metabolic status and metabolic changes with the risk of cardiovascular outcomes have been reported. However, the role of genetic susceptibility underlying these associations remains unexpl.
This program aligns with our strategy to develop lorundrostat in conditions driven by dysregulated aldosterone, with poor cardiovascular outcomes and few treatment options, stated Jon Congleton, Chief Executive Officer of Mineralys Therapeutics. The primary outcome measure is absolute change in the frequency of apnea-hypopnea episodes.
Although some studies have examined the association between the triglyceride glucose-body mass index (TyG-BMI) and cardiovascular outcomes in the cardio-renal-metabolic (CRM) background, none have explored its.
The triglyceride glucose-body mass index (TyG-BMI) is recognized as a reliable surrogate for evaluating insulin resistance and an effective predictor of cardiovascular disease. However, the link between TyG-BM.
This unique setting allowed investigators to examine the relationship between obesity and hemodynamic indices of right ventricular function, as well as how right ventricular function correlates with future clinical outcomes. Original article: Circ Heart Fail. 2023;16:e010524.
This study is designed to investigate the impact of body mass index (BMI) on the short-term outcomes of patients undergoing off-pump coronary artery bypass graft (OPCAB) surgery.
The primary objective was to understand the association between body mass index (BMI) and heart failure with reduced ejection fraction (HFREF) of ischemic etiology in outpatients, using mortality as a parameter. 56–70), BMI 18.5–24.9 = 35.1%, 24.9 = 35.1%, 25–29.9 = 37.2%, 30–34.9 = 17.8%, 35–39.9 = 7%; BMI <18.5 and BMI 18.5–24.9
In addition, abelacimab consistently reduced bleeding risk in patients 75 years of age and older regardless of renal function, body mass index (BMI), and the use of concomitant antiplatelet therapy. The ARR in patients 75 years of age and older was 6.2% compared to 4.2% in patients less than 75 years.
BMI) to receive Roux-en-Y gastric bypass and medical therapy or only receive medical therapy, finding that after five years… Far more gastric bypass patients cut their BP medication use by at least 30% (80.7% The GATEWAY trial assigned 100 participants (76% women, 43.8 of them achieved BPs below 130/80 mm Hg (vs.
Malnutrition is common in stroke patients and leads to worse outcomes. Body mass index (BMI) is a widely available marker of nutrition status, however studies on BMI and post-ICH outcomes are limited and have conflicting results. 7.34) and lobar (OR 3.15, 95% CI 1.67-5.94) 5.94) groups. Albumin (OR 2.27, 95% CI 1.05-4.90)
The primary outcome was inhospital allcause mortality. as BMI increased by category, and it prevailed more frequently among women and older people regardless of their BMI status. kg/m2), normal weight (18.524 kg/m2), overweight (2428 kg/m2), and obese (>28 kg/m2). The incidence of SMuRFlessness declined from 16.2%
Background Catheter ablation (CA) for symptomatic atrial fibrillation (AF) offers the best outcomes for patients. Despite the benefits of CA, a significant proportion of patients suffer a recurrence; hence, there is scope to potentially improve outcomes through technical innovations such as ablation index (AI) guidance during AF ablation.
It incorporates age, body mass index (BMI), and atrial fibrillation to aid in the diagnosis of HFpEF. The newly developed HFpEF-ABA score model estimates the probability of HFpEF in individual patients based on three simple clinical variables: age, BMI, and atrial fibrillation.
BackgroundThe Mendelian randomization approach uses genetic variants as instrumental variables to study the causal association between the risk factors and health outcomes of interest. ResultsIn the rs1229984-instrumented analysis, alcohol drinking was only associated with higher levels of SBP in men and lower levels of DBP in women.
1 If you want the tl;dr, here it is: After 6 weeks on either a low- or high-carb diet, athletes experienced similar performance outcomes during a time-to-exhaustion test , a result that vindicates low-carb diets once and for all. kg/m² reduction in BMI, and decreased their body fat percentage by 1.9%. kg of body weight, saw a 0.7
PET is the most effective form of MPI for detecting CAD iii and is recommended for a wide range of patients, including those considered more challenging to diagnose, such as individuals with a BMI greater than 30 or women, especially those with dense breastsi v , over SPECT MPI.
In the light of increasing availability, the analyses of outcome-relevant predisposing characteristics are of growing importance. The primary outcome was defined as the survival of patients until they were discharged from the hospital, with a favourable neurological outcome [cerebral performance category (CPC) score of ≤2].
IntroductionRecent findings suggest that general anesthesia with endotracheal intubation (GA) in patients with acute ischemic stroke (AIS) due to large vessel occlusion (LVO) who receive mechanical thrombectomy (MT) is associated with similar outcomes to conscious sedation (CS). [1][2] 83 patients received GA and 159 patients received CS.
The primary outcome was to estimate the prevalence of cardiovascular risk factors in patients with hemophilia compared to the general population. Further research is to identify potential ex-specific risk factors that predispose to worse cardiovascular outcomes among patients with hemophilia.
Abstract Introduction Obesity is implicated in adverse atrial remodeling and worse outcomes in patients with atrial fibrillation. The objective of this study is to assess the effect of body mass index (BMI) on ablation-induced scar formation on late gadolinium enhancement cardiac magnetic resonance imaging (LGE-CMR).
Physical fitness was measured using VO2 peak obtained during a maximal exercise test (the gold standard way to measure this outcome). However, body mass index (BMI) was not associated with biological age acceleration. A recent study provides us with some novel insight. vitamin C , Beta-carotene ) — eat your fruits and veggies!
Previous studies have shown that a higher BMI is associated with AF recurrence after AF ablation using conventional thermal ablative modalities, such as radiofrequency (RF) or cryotherapy (Cryo).
Socioeconomic status (SES) is a well-validated risk factor for poor outcomes among patients with heart failure, but its influence on adverse events in patients post-LVAD is poorly understood and may be overestimated. Hispanic ethnicity (17% v 7%, p=0.016) and higher pre-implant BMI (mean 27.5
Limited data indicate an elevated risk of atrial fibrillation (AF) after neoadjuvant chemoradiation in esophageal cancer however the role of AF as an independent predictor of outcomes post-esophagectomy remains under-studied. Outcomes over a 5-year period were mortality, ischemic stroke, and use of anticoagulation.
Pregnant females with a record of bariatric surgical operation have higher cardiovascular adaptation to being pregnant in contrast with females who have comparable early-pregnancy physique mass index (BMI) however no records of weight loss surgery, new records suggest.
Propensity score-matched analysis (PSM) (1:1) was performed on age, gender, BMI, hypertension, diabetes mellitus, chronic kidney disease, hemoglobin level, LDL level, left ventricular ejection fraction and various drugs including beta blockers, ACEi and ARBi.
BMI, body mass index; eGFR, estimated glomerular filtration rate; NYHA, New York Heart Association. Abstract Aims Mineralocorticoid receptor antagonists (MRA) improve outcomes in heart failure with reduced ejection fraction (HFrEF) but are underused.
Out of them, 12% had primary outcomes indicating Status 2 failure. We developed two models: (1) a comprehensive model that included all patients in our cohort and (2) separate models designed for each of the 11 UNOS regions.ResultsWe analyzed data from 4,178 patients listed as Status 2. The models' specificity ranged from 0.75
Propensity score-matched analysis (PSM) (1:1) was performed with matching for age, gender, race, BMI, hypertension, diabetes mellitus, chronic kidney disease, hemoglobin level, low-density lipid (LDL) level, left ventricular ejection fraction, and various drugs including ACEi, ARBi, ARNI, beta-blockers, and diuretics.
K-medoids cluster analysis used LA volume, BMI, baseline fibrosis, and age, resulting in two clusters. Cluster 1 patients were older, had higher baseline fibrosis, higher BMI, and greater LA volume compared to Cluster 2. Results Among 815 patients, 570 served as a training set and 245 as a validation set.
Abstract Aim Patient reported outcomes (PROs) provide important insights into patients’ acceptance of their medical devices. Secondary outcomes included generic QOL using the Medical Outcomes Survey (SF-36) pre-implant and 6-months post-implantation. FPAS and SF-36 were analyzed using ANCOVA.
And the more you exercise, the better your outcomes. On the other hand, people who already have CVD or have suffered a CVD event can significantly improve their long-term outcomes by adopting a structured exercise program. One the one hand, participating in aerobic and resistance exercise reduce the incidence of CVD.
Obesity is associated with increased cardiovascular risk and adverse cardiac changes such as left ventricular hypertrophy (LVH) and in TOF higher body mass index (BMI) contributed to increase risk. Future larger and longitudinal studies are needed to determine if delayed repair in obese patients lead worse remodeling and outcomes.
The primary outcome was any new stroke within three month after onset. Heterogeneity of treatment effect was assessed two ways: using a multivariable outcome prediction model, and a causal forest model. mmol/L, BMI higher than 23.39 Cox proportional hazards models revealed a number needed to treat of 29.4 0.94, p =0.02).Conclusion:Among
We tested for associations between body mass index (BMI), clinical characteristics, cardiac structural and functional abnormalities, physical limitations, quality of life and outcomes with atrial shunt therapy. of patients had BMI ≥30 kg/m 2. Strain measurements in all four chambers were maintained as BMI increased.
Real-World Cardiorenal Metabolic Management Cases Case Study 1: The Multidisciplinary Advantage A groundbreaking study compared outcomes between multi-ethnic patients treated by a multidisciplinary team (MDT) and those managed solely by primary care providers (PCPs).
The primary outcome was the incidence of all-cause dementia within one year post-stroke. They had slightly higher systolic blood pressure, lower BMI, higher rates of comorbidities, and medication use (Table 1). Covariates included demographics, comorbidities, medications, laboratory measures, and vital signs. The sample was 48.4%
Background:Mid-ventricular obstruction (MVO) is a rare subtype of hypertrophic cardiomyopathy (HCM) , but it is associated with severe symptoms and worse clinical outcomes. Circulation, Volume 150, Issue Suppl_1 , Page A4139929-A4139929, November 12, 2024. Whereas the mechanisms of MVO has not fully elucidated.
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