Cardiology Update

DECEMBER 11, 2023

Previous studies have associated obesity with negative changes in the right ventricle using imaging techniques. However, the connection between obesity and more direct measures of right ventricle function, particularly those reflecting hemodynamic consequences, have been unclear. Original article: Circ Heart Fail. 2023;16:e010524.

Obesity 52

Obesity Hospital Outcomes Heart Failure 52

Cardiometabolic Health Congress

JULY 25, 2023

Can you please explain the concept of an obesity paradox? Salvatore Carbone, PhD: First, I’d like to point out that obesity is a major risk factor for cardiometabolic disease. 2, 3] This association is more pronounced for those with class I obesity, which is a body mass index (BMI) between 30-35 kg/m2.

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Obesity BMI Heart Failure Cardiovascular Disease 52

HCPLive

MARCH 11, 2024

New data from the Mayo Clinic show high BMI does not correlate with severe hidradenitis suppurativa in affected children and adolescents.

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Obesity Pediatrics BMI 98

European Journal of Heart Failure

DECEMBER 7, 2023

Increasing severity of obesity is associated with multiple characteristics that may contribute to the development or worsening of heart failure (HF) with preserved ejection fraction (HFpEF). Echocardiography demonstrated increased CO with obesity, but not estimated right atrial (RA) pressure or E/e′. of patients had BMI ≥30 kg/m 2.

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Preserved Ejection Fraction Obesity Heart Failure BMI 40

Journal of Cardiovascular Pharmacology

DECEMBER 11, 2023

The impact of severe obesity on weight-based heparin dosing is not well studied. Lower heparin dose (U/kg) was required in obese patients to achieve target ACT. In conclusion, there is significant variability in the therapeutic effect of heparin, with a lower weight-adjusted heparin dose required in obese patients.

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Science Daily - Heart Disease

FEBRUARY 5, 2024

Bariatric surgery is more effective in controlling hypertension rates, or high blood pressure, in people with obesity and uncontrolled high blood pressure compared to blood pressure medication alone, according to a new study.

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Blood Pressure BMI Obesity Hypertension 97

Open Heart

JUNE 9, 2023

Body mass index (BMI) ‘(weight (kg)/height (m) 2 ) was calculated and patients with BMI ≥30 kg/m 2 were categorised as obese. The mean BMI was 27.48±4.93 kg/m 2 and 23.2% (255) were categorised as obese. to 0.96, p=0.033) for postprocedure in-hospital morbidity. to 7.15, p=0.007).

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Obesity BMI Thrombosis Hospital 52

Journal of Clinical Investigation - Cardiology

SEPTEMBER 3, 2024

Obesity is a known driver of endometrial cancer. Notably, a BMI in the overweight or obese range was paradoxically associated with improved progression-free and overall survival.

Cancer 64

Cancer Obesity BMI Biomarkers 64

European Journal of Heart Failure

DECEMBER 13, 2023

Association between epicardial adipose tissue (EAT) and cardiac dysfunction in severe obesity. BMI, body mass index; GLS, global longitudinal strain; LASct, left atrial contractile strain. Abstract Aim Epicardial adipose tissue (EAT) plays a role in obesity-related heart failure with preserved ejection fraction. p  = 0.045).

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Obesity Preserved Ejection Fraction BMI Heart Failure 40

European Journal of Heart Failure

DECEMBER 22, 2023

Abstract Background N-terminal pro-B-type natriuretic peptide (NT-proBNP) concentrations are lower in patients with obesity. The interaction between body mass index (BMI) and NT-proBNP with respect to heart failure (HF) risk remains incompletely defined. pg/mL lower NT-proBNP per 1 kg/m 2 higher BMI; p<0.001). vs. 0.6%, 1.3%

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Heart Failure BMI Obesity Article 75

HeartRhythm

APRIL 30, 2024

There is scarcity of literature exploring the association between high body mass index (BMI) and cardiac conduction defects (CCD).

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Stroke Journal

FEBRUARY 1, 2024

Meanwhile, Metabolically healthy obesity (MHO) trends are understudied in association with stroke. Patients were categorized into a metabolically healthy obese MHO+ve cohort, BMI&gt; 30, and MHO-ve cohort, BMI&lt;30. Stroke, Volume 55, Issue Suppl_1 , Page ATP262-ATP262, February 1, 2024.

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Obesity Hospital Stroke Strokes 40

Cardiovascular Diabetology

JANUARY 12, 2024

Individuals who are overweight or obese often develop insulin resistance, mediation of the association between body mass index (BMI) and stroke risk through the triglyceride-glucose index (TyG) seems plausible.

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BMI Obesity Stroke Strokes 52

Frontiers in Cardiovascular Medicine

DECEMBER 13, 2023

Background Worldwide obesity has a high prevalence, as well as carries a high risk of several chronic diseases, including hypertension. Studies of the association between obesity and ambulatory blood pressure (BP) are scarce and most use only body mass index (BMI) as indicator of adiposity.

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Blood Pressure BMI Obesity Chronic Disease 64

CardiacWire

FEBRUARY 11, 2024

The associations between obesity and hypertension are widely known, but a new JACC study reveals that weight-reducing gastric bypass surgery has a significant and lasting impact on patients’ need for antihypertensives. The GATEWAY trial assigned 100 participants (76% women, 43.8 of them achieved BPs below 130/80 mm Hg (vs.

Hypertension 111

Hypertension Blood Pressure Obesity BMI 111

Stroke Journal

FEBRUARY 1, 2024

Body mass index (BMI) is a widely available marker of nutrition status, however studies on BMI and post-ICH outcomes are limited and have conflicting results. Patients were divided into underweight, normal weight, overweight, and obese according to World Health Organization BMI criteria. 5.94) groups.

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Hemorrhage BMI Outcomes Coronary Artery Disease 40

Circulation

NOVEMBER 11, 2023

Background:Patients with heart failure (HF) with preserved ejection fraction (HFpEF) and obesity experience high burden of symptoms and functional impairment, and a poor quality of life. Circulation, Ahead of Print. In the STEP-HFpEF trial, once-weekly semaglutide 2.4 mg or placebo for 52 weeks. across domains;P&lt;0.05

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Preserved Ejection Fraction Quality of Life Obesity Heart Failure 40

DAIC

JULY 31, 2024

It incorporates age, body mass index (BMI), and atrial fibrillation to aid in the diagnosis of HFpEF. The newly developed HFpEF-ABA score model estimates the probability of HFpEF in individual patients based on three simple clinical variables: age, BMI, and atrial fibrillation.

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Heart Failure Preserved Ejection Fraction Research Hospital 111

Dr. Paddy Barrett

AUGUST 16, 2024

Overweight/Obesity. Falling into the class of obesity with a BMI of greater than 30 makes this more likely, but so also does having excess visceral fat deposition with significant metabolic consequences at a BMI less than 30. Weight Loss Potential With Obesity Medications. ” here is what I tell them.

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Obesity Blood Pressure Diet Exercise 52

Dr. Paddy Barrett

MAY 24, 2024

All of these patients had a BMI >27. Type 2 diabetes is much more common in those with a BMI in the overweight or obese category but is not uncommon in those who are relatively normal weight. The answer is they were, but just not by conventional BMI standards. But what about those with a relatively normal weight?

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Diabetes Diet BMI Exercise 87

DAIC

MAY 10, 2024

Variable LN morphology on screening mammograms in women with obesity due to ectopic fat deposition. Logistic regression then examined associations between lymph node size, 10-year CVD risk, MACE, T2DM, HTN, low density lipoprotein (LDL), age, and BMI.

Coronary Artery Disease 52

Coronary Artery Disease BMI Obesity Risk Factors 52

Heart 2023 Conference

JULY 17, 2021

Pregnant females with a record of bariatric surgical operation have higher cardiovascular adaptation to being pregnant in contrast with females who have comparable early-pregnancy physique mass index (BMI) however no records of weight loss surgery, new records suggest.

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BMI Blood Pressure Obesity Outcomes 52

Cardiology Update

JANUARY 24, 2024

Growing Global Burden of Cardiometabolic Risks: The 2023 World Obesity Atlas projects a significant rise in global overweight and obesity levels by 2035, leading to a surge in diabetes cases. Strategies promoting healthy aging globally are crucial to mitigate the impact of population aging.

Cardiovascular Disease 119

Cardiovascular Disease Research Blood Pressure Public Health 119

DAIC

MAY 21, 2024

months, participants with baseline body mass index (BMI) above 30 kg/m2 lost 12 pounds, or 5.1% Median age was 53 years, median BP was 134 mm Hg, median TC was 183 mg/dL, LDL-C was 106 mg/dL, and median BMI was 30 kg/m2. of their body weight. Of 102,475 participants, 49.1% were female.

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Blood Pressure Cholesterol Risk Factors BMI 52

DAIC

MARCH 8, 2024

Food and Drug Administration ( FDA ) has approved an additional indication for Wegovy ( semaglutide ) to reduce the risk of major cardiovascular events such as death, heart attack, or stroke in adults with known heart disease and with either obesity or overweight along with a reduced calorie diet and increased physical activity.

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Obesity Heart Disease Heart Attack Heart attacks 111

MIBHS

OCTOBER 31, 2023

Calculate your body mass index (BMI) to determine whether you are within a healthy weight range for your height. If you’re overweight or obese, making gradual changes to your diet and increasing physical activity can help you shed pounds and reduce the strain on your heart.

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Blood Pressure Heart Disease Diet Risk Factors 52

Stroke Journal

FEBRUARY 1, 2024

Conclusion:The global burden of stroke attributable to high BMI in OECD countries highlights the urgent need for comprehensive strategies to address the intertwined challenges of obesity and stroke. Result:The total number of deaths saw a decline from 148,031 (95%UI 85,206-219,328) in 1990 to 143,105 (95%UI: 85,383-209,533) in 2019.

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BMI Stroke Strokes Obesity 40

DAIC

JUNE 26, 2024

Getty Images milla1cf Wed, 06/26/2024 - 18:59 June 26, 2024 — Semaglutide , a medication initially developed for type 2 diabetes and obesity, significantly improves symptoms in men and women with a common type of heart failure that has had few therapeutic options. The study analyzed the effects of semaglutide 2.4

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Preserved Ejection Fraction Obesity BMI Heart Failure 105

Dr. Paddy Barrett

AUGUST 29, 2023

In addition to elevated fasting glucose, there are many other risk factors for developing diabetes, including: Metabolic syndrome BMI > 30 (Obese category) Elevated HBA1c - Not in the diabetes category but above normal. And when you have impaired fasting glucose, you likely have had insulin resistance for MANY years prior.

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Diabetes Risk Factors Heart Attack Heart attacks 52

Open Heart

AUGUST 5, 2022

Objective While greater body mass index (BMI) is associated with increased risk of developing atrial fibrillation (AF), the impact of BMI on outcomes in newly diagnosed AF is unclear. The study population comprised 40 482 participants: 703 underweight (BMI <18.5 kg/m 2 ), 13 095 normal (BMI=18.5–24.9

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Atrial Fibrillation BMI Outcomes Obesity 52

Physiologically Speaking

DECEMBER 15, 2023

For adults with overweight and obesity, resistance exercise increases lean body mass and reduces body fat percentage and fat mass — improving overall body composition. Of course, these benefits can also extend to individuals with a BMI in the normal range.

Physiology 52

Physiology Exercise Blood Pressure Risk Factors 52

Physiologically Speaking

DECEMBER 15, 2023

For adults with overweight and obesity, resistance exercise increases lean body mass and reduces body fat percentage and fat mass — improving overall body composition. Of course, these benefits can also extend to individuals with a BMI in the normal range.

Physiology 52

Physiology Exercise Blood Pressure Risk Factors 52

Physiologically Speaking

DECEMBER 22, 2023

Clinically, about 1/3 of adults have metabolic syndrome — a cluster of conditions including abdominal obesity, high blood pressure, high blood glucose, high triglycerides, and low HDL cholesterol. link] Of course, diet is an important component of metabolic health, but exercise also plays an indispensable role.

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Exercise Physiology Blood Pressure Cholesterol 52

Physiologically Speaking

DECEMBER 22, 2023

Clinically, about 1/3 of adults have metabolic syndrome — a cluster of conditions including abdominal obesity, high blood pressure, high blood glucose, high triglycerides, and low HDL cholesterol. link] Of course, diet is an important component of metabolic health, but exercise also plays an indispensable role.

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Exercise Physiology Blood Pressure Cholesterol 52

Stroke Journal

FEBRUARY 1, 2024

years, p = 0.008) and had enrollment diagnoses of obesity [BMI ≥ 30 kg/m2; 80% (12/15) vs 49% (598/1230), p = 0.016] and hyperlipidemia [87% (13/15) vs 58% (713/1230), p = 0.025]. Statistical significance was ≤ 0.05.Results:Of Participants with rvSSI were younger (54.5 ± 10.2 years vs 61.2 ± 10.6

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Risk Factors BMI Obesity Stroke 40

DAIC

MARCH 5, 2024

They adjusted for the participants' use of tobacco and other characteristics, including their age, sex, race, body mass index or BMI, obesity, diabetes, physical activity levels, and socioeconomic status.

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Heart Attack Heart attacks Stroke Strokes 98

Wellnest

JULY 19, 2023

However, recent studies have observed that people below 40 are also experiencing heart attacks due to high blood pressure, cholesterol, diabetes, smoking, obesity, a sedentary lifestyle, and social and mental stress. Obesity or being overweight can increase the risk of heart disease. So, how do you recognize a heart attack?

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Heart Attack Heart attacks Blood Pressure Myocardial Infarction 52