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(MedPage Today) -- Liraglutide (Saxenda) added to lifestyle intervention helped reduce BMI in young children with obesity, the phase IIIa SCALE Kids trial found. By week 56, kids, ages 6 to <12 years, on once-daily 3-mg liraglutide lost 5.8.
This study aims to investigate the impact of weight loss after LSG on the left ventricular myocardial work (LVMW) in obese patients and explore the clinical value of the left ventricular pressure - strain loop (LV - PSL).MethodsThirty
(MedPage Today) -- Medical experts from around the globe proposed a more nuanced approach to diagnosing obesity that does not rely exclusively on body mass index (BMI) alone. Writing in The Lancet Diabetes & Endocrinology, the global commission.
BackgroundIndividuals diagnosed with type 2 diabetes mellitus (T2DM) commonly exhibit elevated lipid levels and an increased body mass index (BMI). The impact of BMI on the efficacy of statins in reducing lipid levels among diabetic patients remains uncertain.
Patients with lean NAFLD had fewer metabolic comorbidities but maintained similar risk of NASH, cirrhosis, nonliver cancer, and mortality compared to their overweight and obese counterparts.
These results highlight the potential of preventing increasing CKD burden and of preventing subsequent cardiovascular conditions, especially given current rates of obesity among adolescents.
(MedPage Today) -- Tirzepatide (Zepbound) was effective at reducing body weight in Chinese adults with lower cutoffs for overweight or obesity, the SURMOUNT-CN trial reported. In the study of 210 adults without diabetes, participants on tirzepatide.
Preventive Services Task Force (USPSTF) plans to recommend intensive behavioral interventions -- but not pharmacologic therapies -- for kids with a high body mass index (BMI). (MedPage Today) -- The U.S. In its draft recommendation statement.
In today’s society, the prevalence of obesity has become a significant concern. have obesity, and this rate has increased by more than 10 percentage points in the past two decades. Understanding the prevalence of obesity is crucial in comprehending why events like Healthy Weight Week are essential. of adults in the U.S.
Bariatric surgery is more effective in controlling hypertension rates, or high blood pressure, in people with obesity and uncontrolled high blood pressure compared to blood pressure medication alone, according to a new study.
Obesity, a pervasive health concern, has been identified as a significant risk factor for ATAAD, introducing unique surgical challenges that can influence postoperative outcomes. Based on BMI (WS/T 428-2013), patients were categorized into normal weight, overweight, and obese. Results The average age of the cohort was 50.1 ± 11.2
Obesity is a widespread public health challenge in the Middle East, maintaining prevalence in 54.2% Overweight and obese women have a higher risk of hypertension and cardiovascular risk factors than women with a standard BMI, according to an analysis of the ANCORS-YW STUDY presented at ACC Middle East 2024. of women and 31.4%
Obesity is a complex, diverse and multifactorial disease that has become a major public health concern in the last decades. The current classification systems relies on anthropometric measurements, such as BMI.
Previous studies have associated obesity with negative changes in the right ventricle using imaging techniques. However, the connection between obesity and more direct measures of right ventricle function, particularly those reflecting hemodynamic consequences, have been unclear. Original article: Circ Heart Fail. 2023;16:e010524.
Abstract Background N-terminal pro-B-type natriuretic peptide (NT-proBNP) concentrations are lower in patients with obesity. The interaction between body mass index (BMI) and NT-proBNP with respect to heart failure (HF) risk remains incompletely defined. pg/mL lower NT-proBNP per 1 kg/m 2 higher BMI; p<0.001). vs. 0.6%, 1.3%
Visceral Fat & Insulin Resistance While rates of smoking have decreased significantly in recent decades, the rates of obesity and excess visceral fat have increased dramatically 3. Trends in the number of obese and severely obese people by region. Relationship of BMI and Risk Of Diabetes. Obesity (Silver Spring).
Background:Impaired left atrial (LA) function is observed in obese patients, however, there is little information on when LA dysfunction begins to appear. To clarify this issue, we assessed LA volume and function in obese infants.Methods:Two-dimensional speckle-tracking echocardiography was performed in 96 infants aged 4 months.
The associations between obesity and hypertension are widely known, but a new JACC study reveals that weight-reducing gastric bypass surgery has a significant and lasting impact on patients’ need for antihypertensives. The GATEWAY trial assigned 100 participants (76% women, 43.8 of them achieved BPs below 130/80 mm Hg (vs.
Obesity is associated with increased cardiovascular risk and adverse cardiac changes such as left ventricular hypertrophy (LVH) and in TOF higher body mass index (BMI) contributed to increase risk. In the presence of obesity, RVEDVi may underestimate the severity of RV volume load. mL/m2, p=0.04; RVEDVi 157.4±21.5 vs RVEDV 297.6±56.6
Increasing severity of obesity is associated with multiple characteristics that may contribute to the development or worsening of heart failure (HF) with preserved ejection fraction (HFpEF). Echocardiography demonstrated increased CO with obesity, but not estimated right atrial (RA) pressure or E/e′. of patients had BMI ≥30 kg/m 2.
The Kobe University finding adds another aspect to the obesity paradox but also highlights the importance of considering the population's normal when recommending best practices. Slightly overweight stroke survivors have a lower risk of sustaining disabilities.
Background Worldwide obesity has a high prevalence, as well as carries a high risk of several chronic diseases, including hypertension. Studies of the association between obesity and ambulatory blood pressure (BP) are scarce and most use only body mass index (BMI) as indicator of adiposity.
Body mass index (BMI) ‘(weight (kg)/height (m) 2 ) was calculated and patients with BMI ≥30 kg/m 2 were categorised as obese. The mean BMI was 27.48±4.93 kg/m 2 and 23.2% (255) were categorised as obese. to 0.96, p=0.033) for postprocedure in-hospital morbidity. to 7.15, p=0.007).
The impact of severe obesity on weight-based heparin dosing is not well studied. Lower heparin dose (U/kg) was required in obese patients to achieve target ACT. In conclusion, there is significant variability in the therapeutic effect of heparin, with a lower weight-adjusted heparin dose required in obese patients.
Optimal NT-proBNP cut points for HFpEF rule out (optimizing sensitivity) and rule in (optimizing specificity) were derived and tested, stratified by obesity and atrial fibrillation. Current consensus age- and BMI-stratified rule-in thresholds demonstrated only 65% specificity (95% CI, 57%72%).
It incorporates age, body mass index (BMI), and atrial fibrillation to aid in the diagnosis of HFpEF. The newly developed HFpEF-ABA score model estimates the probability of HFpEF in individual patients based on three simple clinical variables: age, BMI, and atrial fibrillation.
Association between epicardial adipose tissue (EAT) and cardiac dysfunction in severe obesity. BMI, body mass index; GLS, global longitudinal strain; LASct, left atrial contractile strain. Abstract Aim Epicardial adipose tissue (EAT) plays a role in obesity-related heart failure with preserved ejection fraction. p = 0.045).
Obesity is associated with reduced catheter ablation-induced scar formation on late-gadolinium enhancement MRI. Abstract Introduction Obesity is implicated in adverse atrial remodeling and worse outcomes in patients with atrial fibrillation. Ablation parameters and lesion delivery were not dependent on BMI.
Individuals who are overweight or obese often develop insulin resistance, mediation of the association between body mass index (BMI) and stroke risk through the triglyceride-glucose index (TyG) seems plausible.
kg/m2), normal weight (18.524 kg/m2), overweight (2428 kg/m2), and obese (>28 kg/m2). kg/m2), normal weight (18.524 kg/m2), overweight (2428 kg/m2), and obese (>28 kg/m2). as BMI increased by category, and it prevailed more frequently among women and older people regardless of their BMI status.
Variants of the G protein–coupled receptor 75 (GPR75) are associated with a lower BMI in large-scale human exome-sequencing studies. Additionally, GPR75 was localized in the primary cilia of hypothalamic cells, whereas the Thinner mutation (L144P) and human GPR75 variants in individuals with a lower BMI failed to localize in the cilia.
Body mass index (BMI) is a widely available marker of nutrition status, however studies on BMI and post-ICH outcomes are limited and have conflicting results. Patients were divided into underweight, normal weight, overweight, and obese according to World Health Organization BMI criteria. 5.94) groups.
BackgroundWeight-adjusted waist circumference index (WWI) is a novel index related to obesity and has been associated with the risk and prognosis of several diseases. cm/√kg was identified for predicting myocardial infarction, outperforming waist circumference and body mass index (BMI). When WWI exceeded 10.97 cm/√kg,
Pregnant females with a record of bariatric surgical operation have higher cardiovascular adaptation to being pregnant in contrast with females who have comparable early-pregnancy physique mass index (BMI) however no records of weight loss surgery, new records suggest.
Overweight/Obesity. Falling into the class of obesity with a BMI of greater than 30 makes this more likely, but so also does having excess visceral fat deposition with significant metabolic consequences at a BMI less than 30. Weight Loss Potential With Obesity Medications. ” here is what I tell them.
Older adults with obesity and metabolic syndrome may have decreased elimination of the xylitol metabolite xylose, which may explain the higher observed risk of thrombosis and stroke in older adults who consume foods with sugar alcohols. The mean BMI was 35.2 kg/m2, HbA1c was 5.9% 0.4,
Based on the finetuned NN, we predicted risk markers within an independent cohort of 48,376 patients with a history of T2D, ASCVD, or obesity and emulated a target trial to evaluate the subclinical effect of GLP1RA. Compared to the control group, the GLP1RA cohort had a higher baseline risk profile (BMI: 35.1 [SD Hispanic, 9.6%
Variable LN morphology on screening mammograms in women with obesity due to ectopic fat deposition. Logistic regression then examined associations between lymph node size, 10-year CVD risk, MACE, T2DM, HTN, low density lipoprotein (LDL), age, and BMI.
A physical examination was performed, heart rate was assessed, blood pressure was measured according to Korotkov method, body mass index (BMI) was calculated. At the same time, 23 pregnant women (95.8%) with CHT were overweight, of which 15(62.5%) were women with obesity of the I and II degree. Heart rate in group 1 was 89.8±12.2
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