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Genetically predicted smoking and body mass index mediate the relationship between insomnia and myocardial infarction

Frontiers in Cardiovascular Medicine

Genetic instruments for MI, smoking initiation, alcohol consumption, and BMI were derived from large-scale genome-wide association studies. Smoking initiation and BMI were identified as potential mediators. ConclusionsThe results of this MR analysis demonstrate that insomnia increases the risk of MI.

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Association between weight-adjusted waist circumference index and myocardial infarction: results from the national health and nutrition examination survey, 1999–2014

Frontiers in Cardiovascular Medicine

Multiple logistic regression and restricted cubic spline (RCS) analyses were conducted to assess both linear and nonlinear associations between WWI and myocardial infarction. Subgroup analyses and interaction tests were also performed.ResultsAmong the 31,535 participants analyzed, 1,449 (4.82%) had experienced a myocardial infarction.

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Associations of triglyceride glucose-body mass index and the combination of sedentary behavior and physical activity with risks of all-cause mortality and myocardial infarction: a cohort study from the UK biobank

Cardiovascular Diabetology

Triglyceride glucose-body mass (TyG-BMI) index, sedentary behavior (SB) and physical activity (PA) are independently associated with all-cause mortality and myocardial infarction (MI). However, it remains uncl.

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In‐Hospital Outcomes in Patients With Acute Myocardial Infarction and No Standard Modifiable Cardiovascular Risk Factors Across Varying Body Mass Index: Findings From the CCC‐ACS Project

Journal of the American Heart Association

Multivariable logistic regression models were used to estimate BMIstratified associations between SMuRFless status and outcomes.ResultsThe study included 44 538 patients with firstpresentation acute myocardial infarction, of whom 4454 were SMuRFless. The primary outcome was inhospital allcause mortality.

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Abstract 4148106: Hemophilia and Cardiovascular disease in the United States: Prevalence, Risk factors, and outcomes.

Circulation

The secondary outcomes comprise the odds of adverse events, including myocardial infarction, ischemic stroke, transient ischemic attack (TIA), occlusive atherosclerotic disease, percutaneous coronary intervention, and coronary artery bypass graft (CABG)., The hemophilia cohort was slightly older (63.2[16.8]

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Abstract 4142589: GLP-1 receptor agonists slow the progression of subclinical cardiovascular risk as detected from 12-lead electrocardiograms

Circulation

The primary analysis compared percentile rank transformed ECG markers for GLP1RA and non-GLP1RA patients using inverse probability weighted (IPW) linear regression models, adjusted for key variables including demographics, comorbidities, medications, HbA1c, and BMI at baseline. years old, predominantly female (56%), and racially diverse: 46.6%

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A man in his 40s with 3 days of stuttering chest pain

Dr. Smith's ECG Blog

Written by Willy Frick A man in his early 40s with BMI 36, hypertension, and a 30 pack-year smoking history presented with three days of chest pain. By definition , this is acute myocardial infarction, the only question now is the etiology. It started while he was at rest after finishing a workout.