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BMI in Late Adolescence Linked to Early Chronic Kidney Disease

HCPLive

These results highlight the potential of preventing increasing CKD burden and of preventing subsequent cardiovascular conditions, especially given current rates of obesity among adolescents.

BMI 105
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Discontinuation and reinitiation of mineralocorticoid receptor antagonists in patients with heart failure and reduced ejection fraction

European Journal of Heart Failure

BMI, body mass index; eGFR, estimated glomerular filtration rate; NYHA, New York Heart Association. Discontinuation occurred early and was more common in patients with advanced kidney disease, hyperkalaemia, lack of follow-up in specialty care, more severe heart failure, comorbidities, and markers of sociodemographic frailty.

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Association between asthma and cardiovascular disease: evidence from the national health and nutrition examination survey 1999–2018

Frontiers in Cardiovascular Medicine

Asthma significantly increased the prevalence of stroke among participants aged 1844 years old, with a BMI 18.5029.99kg/m2, with low education levels, and with a PIR<1.00. Asthma also increased the prevalence of angina in females, non-Hispanic Blacks, participants aged 4559 years old, with a BMI30.00kg/m2, and with a PIR<1.00.

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Abstract WP319: Reliability and validity of self-reported risk factors for stroke and dementia

Stroke Journal

Reliability of self-reported risk factors was high in overweight (F1 0.81) and diabetes (F1 0.71), moderate in hearing impairment (F1 0.59) and hypertension (F1 0.56) and low in hypercholesterolemia (F1 0.49) and kidney disease (F1 0.25).

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Association between “Life's Essential 8” cardiovascular health and apparent treatment-resistant hypertension among US adults from the NHANES, 2005 to 2018

Frontiers in Cardiovascular Medicine

Physical activity (PA), body mass index (BMI), and blood glucose were associated with aTRH (all p-values<0.05), while diet, nicotine exposure, sleep, and blood lipids were not significantly associated with aTRH. Compared to subjects with low CVH, participants with moderate and high CVH exhibited lower risks of 47% and 76%, respectively.

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Abstract WP294: Racial Disparities among the risk of Stroke and other clinical outcomes post Infective Endocarditis: A Propensity Matched Analysis

Stroke Journal

Propensity score-matched analysis (PSM) (1:1) was performed on age, gender, BMI, hypertension, diabetes mellitus, chronic kidney disease, hemoglobin level, LDL level, left ventricular ejection fraction and various drugs including beta blockers, ACEi and ARBi. Both groups were followed for 12 months.

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Mineralys Therapeutics Announces Phase 2 Clinical Trial of Lorundrostat

DAIC

a clinical-stage biopharmaceutical company focused on developing medicines to target hypertension, chronic kidney disease (CKD) and other diseases, hasannounced that the U.S. Subjects will be at least 18 years old, with a BMI 27 kg/m 2 , and the trial will be conducted across approximately 40 sites.