Physiologically Speaking

JANUARY 26, 2024

However, there’s not great evidence that multivitamins benefit specific health outcomes. This hypothesis was studied in a randomized controlled trial known as the COcoa Supplement and Multivitamin Outcomes Study or COSMOS. Nutritional insurance? A health- and longevity-boosting powerhouse? Perhaps not.

Physiology 52

Physiology Diet Cardiovascular Disease BMI 52

Circulation

NOVEMBER 11, 2024

Introduction:The demographics of patients with pulmonary arterial hypertension (PAH) is shifting towards older age, increased comorbidity burden, and an increase in the risk of left ventricular (LV) diastolic dysfunction. Survival analysis was performed (Outcome: PAH related-hospitalization or death). 2022 were included.

Pulmonary 40

Pulmonary Hypertension Preserved Ejection Fraction Outcomes 40

Open Heart

AUGUST 5, 2022

Objective While greater body mass index (BMI) is associated with increased risk of developing atrial fibrillation (AF), the impact of BMI on outcomes in newly diagnosed AF is unclear. The study population comprised 40 482 participants: 703 underweight (BMI <18.5 kg/m 2 ), 13 095 normal (BMI=18.5–24.9

Atrial Fibrillation 52

Atrial Fibrillation BMI Outcomes Obesity 52

European Journal of Heart Failure

DECEMBER 18, 2024

Association between body mass index (BMI) and clinical outcomes in PARADISE-MI. ( A ) Histogram for BMI (kg/m 2 ), ( B ) adverse events for BMI subgroups, and spline model curves for ( C ) the primary composite outcome and ( D ) cardiovascular (CV) death by BMI subgroups.

Myocardial Infarction 40

Myocardial Infarction BMI Outcomes Heart Failure 40

Cardiometabolic Health Congress

JULY 25, 2023

There are significant data that show that if you have obesity, you have a high risk of developing coronary heart disease, heart failure, type 2 diabetes (T2D) or risk factors such as hypertension and dyslipidemia. [1] These individuals tend to have a better prognosis when compared to both individuals with normal weight (BMI of 18.5

Obesity 52

Obesity BMI Heart Failure Cardiovascular Disease 52

Stroke Journal

FEBRUARY 1, 2024

Background:Obesity has been associated with an increase in the risk of stroke and poor outcomes. Patients were categorized into a metabolically healthy obese MHO+ve cohort, BMI&gt; 30, and MHO-ve cohort, BMI&lt;30. Stroke, Volume 55, Issue Suppl_1 , Page ATP262-ATP262, February 1, 2024.

Obesity 40

Obesity Hospital Stroke Strokes 40

DAIC

JUNE 26, 2024

mg administered to participants once weekly vs placebo on the STEP-HFpEF program’s dual primary and confirmatory secondary, and exploratory outcomes by sex. Semaglutide-mediated improvements in HF-related symptoms and physical limitations were consistent in both male and female participants across key subgroups including age and BMI.

Preserved Ejection Fraction 105

Preserved Ejection Fraction Obesity BMI Heart Failure 105

Circulation

NOVEMBER 11, 2024

Background:Research into pulmonary hypertension (PH) reveals significant sex-based disparities in long-term survival rates. Notably, women, despite being more susceptible to PH, often experience better survival outcomes than men—a phenomenon possibly linked to the "estrogen paradox."

Pulmonary 40

Pulmonary Hypertension BMI Outcomes 40

DAIC

MAY 21, 2024

The study is the largest and most robust of its kind to date, examining 102,475 Hello Heart users with high BP (hypertension) between January 2018 and December 2022. months, participants with baseline body mass index (BMI) above 30 kg/m2 lost 12 pounds, or 5.1% of their body weight. Of 102,475 participants, 49.1% were female.

Blood Pressure 52

Blood Pressure Cholesterol Risk Factors BMI 52

Stroke Journal

JANUARY 30, 2025

We sought to identify the differential clinical and neuroimaging characteristics, and outcomes in matched AIS cohorts from Norway (NOR) and the United States (US).Methods:AIS Cohorts were matched on age, sex, diabetes, atrial fibrillation, and hypertension. Likewise, WMH burden was similar across cohorts.

Stroke 40

Stroke Strokes Thrombolysis Atrial Fibrillation 40

European Journal of Heart Failure

DECEMBER 10, 2024

Then identified clusters are predicted and tested in the learning set to evaluate their association with outcomes. Clusters were significantly associated with outcomes in derivation and validation datasets, with Cluster 1 having the highest risk, and Cluster 4 the lowest.

Heart Failure 40

Heart Failure Peripheral Arterial Disease Blood Pressure Atrial Fibrillation 40

Dr. Paddy Barrett

MARCH 23, 2024

When broken down by disease category, cardiovascular disease, cancer, dementia, stroke, osteoarthritis, hypertension and stroke, the pattern is the same. There is very little we can do to avoid these outcomes, but we can set the odds in our favour to delay the onset of the major chronic disease that is likely to be our cause of death.

Chronic Disease 106

Chronic Disease Quality of Life Dementia Cancer 106

Physiologically Speaking

DECEMBER 15, 2023

Participating in any resistance training is associated with a 15%–17% lower risk for these outcomes compared to non-participation. Of course, these benefits can also extend to individuals with a BMI in the normal range.

Physiology 52

Physiology Exercise Blood Pressure Risk Factors 52

Physiologically Speaking

DECEMBER 15, 2023

Participating in any resistance training is associated with a 15%–17% lower risk for these outcomes compared to non-participation. Of course, these benefits can also extend to individuals with a BMI in the normal range.

Physiology 52

Physiology Exercise Blood Pressure Risk Factors 52

Circulation

NOVEMBER 11, 2024

Introduction:Atrial fibrillation (AF) is a common cardiac arrhythmia, the risk of cardiovascular adverse outcome rises when it coexists with acute coronary syndrome (ACS) or undergoing percutaneous coronary intervention (PCI). The restrictive cubic spline in Figure 2 showed that LVEDD greater than 60 mm increased the risk of MACEs.

Atrial Fibrillation 40

Atrial Fibrillation Coronary Artery Bypass Graft Coronary Artery Disease Myocardial Infarction 40

Cardiometabolic Health Congress

OCTOBER 30, 2024

This underscores the importance of early detection and management of both conditions to prevent severe outcomes. Case Study: A Common Clinical Scenario This case study highlights the complex relationship between metabolic disease and liver health.

Diabetes 93

Diabetes Exercise Obesity BMI 93