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Gastric Bypass Surgery’s Durable Hypertension Impact

CardiacWire

The associations between obesity and hypertension are widely known, but a new JACC study reveals that weight-reducing gastric bypass surgery has a significant and lasting impact on patients’ need for antihypertensives. vs. 2.4%) All gastric bypass patients eliminated their resistant hypertension (from 15.2%

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Why Mechanical AVR Valves Still Matter

CardiacWire

They also often had lower BMI (31.0 Bioprosthetic patients also had higher rates of hypertension (78.7% The studys design also wasnt powered to make any certain conclusions due to its reliance on registry data, meaning a randomized head-to-head trial would be needed to confirm these outcomes. vs 71.8%) or prior PCI (6.7

BMI 80
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Mineralys Therapeutics Announces Phase 2 Clinical Trial of Lorundrostat

DAIC

a clinical-stage biopharmaceutical company focused on developing medicines to target hypertension, chronic kidney disease (CKD) and other diseases, hasannounced that the U.S. We believe suppression of aldosterone production by lorundrostat has the potential to reduce the nocturnal hypertension driving adverse cardiovascular outcomes.

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Abstract 4146852: Impact of Left Ventricular Diastolic Function in Pulmonary Arterial Hypertension Outcomes

Circulation

Introduction:The demographics of patients with pulmonary arterial hypertension (PAH) is shifting towards older age, increased comorbidity burden, and an increase in the risk of left ventricular (LV) diastolic dysfunction. Survival analysis was performed (Outcome: PAH related-hospitalization or death). 2022 were included.

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Association between body mass index and clinical outcomes in patients with acute myocardial infarction and reduced systolic function: Analysis of PARADISE‐MI trial data

European Journal of Heart Failure

Association between body mass index (BMI) and clinical outcomes in PARADISE-MI. ( A ) Histogram for BMI (kg/m 2 ), ( B ) adverse events for BMI subgroups, and spline model curves for ( C ) the primary composite outcome and ( D ) cardiovascular (CV) death by BMI subgroups.

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Abstract TP262: Trends, Odds, Burdens and Outcomes of Metabolically Healthy Obesity in Stroke Related Hospitalizations of Elderly Patients - A Nationwide Analysis, 2016-2019

Stroke Journal

Background:Obesity has been associated with an increase in the risk of stroke and poor outcomes. Patients were categorized into a metabolically healthy obese MHO+ve cohort, BMI> 30, and MHO-ve cohort, BMI<30. Stroke, Volume 55, Issue Suppl_1 , Page ATP262-ATP262, February 1, 2024.

Obesity 40
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Abstract WP294: Racial Disparities among the risk of Stroke and other clinical outcomes post Infective Endocarditis: A Propensity Matched Analysis

Stroke Journal

Propensity score-matched analysis (PSM) (1:1) was performed on age, gender, BMI, hypertension, diabetes mellitus, chronic kidney disease, hemoglobin level, LDL level, left ventricular ejection fraction and various drugs including beta blockers, ACEi and ARBi.