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University Hospitals Researcher Develops New Score System to Better Screen and Treat HFpEF Heart Failure Patients

DAIC

mtaschetta-millane Wed, 07/31/2024 - 06:00 July 31, 2024 — A novel study co-authored by a heart failure cardiologist at University Hospitals Harrington Heart & Vascular Institute, demonstrates the effectiveness of a newly developed scoring system in identifying patients with Heart Failure with Preserved Ejection Fraction (HFpEF).

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Adiposity, fat-free mass and incident heart failure in 500 000 individuals

Open Heart

Background and aims The independent role of body fat distribution and fat-free mass in heart failure (HF) risk is unclear. Overall, HF risk was more strongly associated with central adiposity (waist circumference (WC) adjusted for body mass index (BMI); HR 1.38, 95% CI 1.32 years, 44% male) from the UK Biobank. to 1.33).

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The Finer Points of FINEARTS-HF

CardiacWire

Bayers FINEARTS-HF study revealed that finerenone could be poised to become the next big heart failure treatment at ESC 2024, and a new series of JACC sub-studies just further strengthened its case. Finerenone (Bayers Kerendia) got its start with CKD, and is the first mineralocorticoid receptor antagonist to be used for HF.

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Natriuretic Peptides, Body Mass Index and Heart Failure Risk: Pooled Analyses of SAVOR?TIMI 53, DECLARE?TIMI 58 and CAMELLIA?TIMI 61

European Journal of Heart Failure

The interaction between body mass index (BMI) and NT-proBNP with respect to heart failure (HF) risk remains incompletely defined. Hospitalization for heart failure (HHF) was examined across strata of baseline BMI and NT-proBNP. pg/mL lower NT-proBNP per 1 kg/m 2 higher BMI; p<0.001).

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Comparative study on the predictive value of TG/HDL-C, TyG and TyG-BMI indices for 5-year mortality in critically ill patients with chronic heart failure: a retrospective study

Cardiovascular Diabetology

The triglyceride glucose (TyG) index, TyG-body mass index (TyG-BMI), and triglyceride-density lipoprotein cholesterol ratio (TG/HDL-C) are substitute indicators for insulin resistance (IR). This study aimed to.

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Heart failure, chronic obstructive pulmonary disease and efficacy and safety of dapagliflozin in heart failure with mildly reduced or preserved ejection fraction: Insights from DELIVER

European Journal of Heart Failure

BMI, body mass index; CI, confidence interval; LVEF, left ventricular ejection fraction; NT-proBNP, N-terminal pro-B-type natriuretic peptide. BMI, body mass index; CI, confidence interval; LVEF, left ventricular ejection fraction; NT-proBNP, N-terminal pro-B-type natriuretic peptide. 0.93]; COPD: HR 0.82 [95% CI 0.62–1.10];

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Discontinuation and reinitiation of mineralocorticoid receptor antagonists in patients with heart failure and reduced ejection fraction

European Journal of Heart Failure

Discontinuation and reinitiation of mineralocorticoid receptor antagonists (MRA) in patients with heart failure and reduced ejection fraction (HFrEF). BMI, body mass index; eGFR, estimated glomerular filtration rate; NYHA, New York Heart Association.