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BackgroundIndividuals diagnosed with type 2 diabetes mellitus (T2DM) commonly exhibit elevated lipid levels and an increased body mass index (BMI). The impact of BMI on the efficacy of statins in reducing lipid levels among diabetic patients remains uncertain.
(MedPage Today) -- Medical experts from around the globe proposed a more nuanced approach to diagnosing obesity that does not rely exclusively on body mass index (BMI) alone. Writing in The Lancet Diabetes & Endocrinology, the global commission.
No Diabetes or Pre-Diabetes. A study of almost 10,000 adults with obesity (BMI >30) who were evaluated for all LE8 factors and followed for over 7 years can give us some insight 1. Can we take the obesity risk off the table also? 3 Incretin-based therapies for the treatment of obesity-related diseases.
(MedPage Today) -- Tirzepatide (Zepbound) was effective at reducing body weight in Chinese adults with lower cutoffs for overweight or obesity, the SURMOUNT-CN trial reported. In the study of 210 adults without diabetes, participants on tirzepatide.
In the US, over 45% of the population has either diabetes or pre-diabetes 1. The absolute majority of those with diabetes have type 2 diabetes, which is usually associated with excess visceral fat and poor cardiometabolic health. Because a diagnosis of diabetes is very likely to shorten your life. Pre-Diabetes.
In today’s society, the prevalence of obesity has become a significant concern. have obesity, and this rate has increased by more than 10 percentage points in the past two decades. Understanding the prevalence of obesity is crucial in comprehending why events like Healthy Weight Week are essential. of adults in the U.S.
Visceral Fat & Insulin Resistance While rates of smoking have decreased significantly in recent decades, the rates of obesity and excess visceral fat have increased dramatically 3. Trends in the number of obese and severely obese people by region. Relationship of BMI and Risk Of Diabetes. Losing 6.5%
Can you please explain the concept of an obesity paradox? Salvatore Carbone, PhD: First, I’d like to point out that obesity is a major risk factor for cardiometabolic disease. 2, 3] This association is more pronounced for those with class I obesity, which is a body mass index (BMI) between 30-35 kg/m2.
The associations between obesity and hypertension are widely known, but a new JACC study reveals that weight-reducing gastric bypass surgery has a significant and lasting impact on patients’ need for antihypertensives. The GATEWAY trial assigned 100 participants (76% women, 43.8 of them achieved BPs below 130/80 mm Hg (vs.
Increasing severity of obesity is associated with multiple characteristics that may contribute to the development or worsening of heart failure (HF) with preserved ejection fraction (HFpEF). Echocardiography demonstrated increased CO with obesity, but not estimated right atrial (RA) pressure or E/e′. of patients had BMI ≥30 kg/m 2.
It all comes down to: What your priorities are What your objectives are Your risk tolerance Your ability to update that risk model Where you draw the line of ‘risk’ equating to ‘causation’ The same is true when it comes to the question of statins ‘causing’ diabetes. What to do? Let’s dive in.
Meanwhile, Metabolically healthy obesity (MHO) trends are understudied in association with stroke. Patients were categorized into a metabolically healthy obese MHO+ve cohort, BMI> 30, and MHO-ve cohort, BMI<30. Stroke, Volume 55, Issue Suppl_1 , Page ATP262-ATP262, February 1, 2024.
Growing Global Burden of Cardiometabolic Risks: The 2023 World Obesity Atlas projects a significant rise in global overweight and obesity levels by 2035, leading to a surge in diabetes cases. Strategies promoting healthy aging globally are crucial to mitigate the impact of population aging.
Body mass index (BMI) is a widely available marker of nutrition status, however studies on BMI and post-ICH outcomes are limited and have conflicting results. Patients were divided into underweight, normal weight, overweight, and obese according to World Health Organization BMI criteria. 5.94) groups.
Older adults with obesity and metabolic syndrome may have decreased elimination of the xylitol metabolite xylose, which may explain the higher observed risk of thrombosis and stroke in older adults who consume foods with sugar alcohols. The mean BMI was 35.2 kg/m2, HbA1c was 5.9% 0.4,
Overweight/Obesity. Falling into the class of obesity with a BMI of greater than 30 makes this more likely, but so also does having excess visceral fat deposition with significant metabolic consequences at a BMI less than 30. Weight Loss Potential With Obesity Medications. ” here is what I tell them.
Background:GLP-1 receptor agonists (GLP1RA) agonists have been shown to reduce cardiovascular events in patients with type 2 diabetes (T2D) and atherosclerotic cardiovascular disease (ASCVD). Compared to the control group, the GLP1RA cohort had a higher baseline risk profile (BMI: 35.1 [SD Hispanic, 9.6% Asian, and 4.6% Hispanic, 9.6%
Variable LN morphology on screening mammograms in women with obesity due to ectopic fat deposition. Logistic regression then examined associations between lymph node size, 10-year CVD risk, MACE, T2DM, HTN, low density lipoprotein (LDL), age, and BMI.
The mean BMI was 27.9 kg/m2, with 4 classified as obese. One patient had diabetes, 8 had hyperlipidemia, and 9 had hypertension. Of these, 9 (64%) were female with a mean age of 59.6, and 5 (36%) were male with a mean age of 55.4. All patients were nonsmokers; 2 had a family history of stroke.
Calculate your body mass index (BMI) to determine whether you are within a healthy weight range for your height. If you’re overweight or obese, making gradual changes to your diet and increasing physical activity can help you shed pounds and reduce the strain on your heart.
Blood glucose control Resistance exercise training can reduce fasting glucose by 2–5 mg/dL in adults with prediabetes and type 2 diabetes but doesn’t seem to reduce blood glucose in healthy adults (not surprising). Of course, these benefits can also extend to individuals with a BMI in the normal range. a higher metabolism).
Blood glucose control Resistance exercise training can reduce fasting glucose by 2–5 mg/dL in adults with prediabetes and type 2 diabetes but doesn’t seem to reduce blood glucose in healthy adults (not surprising). Of course, these benefits can also extend to individuals with a BMI in the normal range. a higher metabolism).
Food and Drug Administration ( FDA ) has approved an additional indication for Wegovy ( semaglutide ) to reduce the risk of major cardiovascular events such as death, heart attack, or stroke in adults with known heart disease and with either obesity or overweight along with a reduced calorie diet and increased physical activity.
Getty Images milla1cf Wed, 06/26/2024 - 18:59 June 26, 2024 — Semaglutide , a medication initially developed for type 2 diabetes and obesity, significantly improves symptoms in men and women with a common type of heart failure that has had few therapeutic options. The study analyzed the effects of semaglutide 2.4
Objective While greater body mass index (BMI) is associated with increased risk of developing atrial fibrillation (AF), the impact of BMI on outcomes in newly diagnosed AF is unclear. The study population comprised 40 482 participants: 703 underweight (BMI <18.5 kg/m 2 ), 13 095 normal (BMI=18.5–24.9
The lower part of the figure shows the risk of mortality according to continuous body mass index (BMI) ( left panel ) and waist-to-height ratio (WHtR) ( right panel ). Compared to a BMI 18.524.9kg/m 2 , a BMI <18.5kg/m 2 ( n =24) was associated with a numerically, but not a significantly, higher risk of all-cause and cardiovascular death.
They adjusted for the participants' use of tobacco and other characteristics, including their age, sex, race, body mass index or BMI, obesity, diabetes, physical activity levels, and socioeconomic status.
However, recent studies have observed that people below 40 are also experiencing heart attacks due to high blood pressure, cholesterol, diabetes, smoking, obesity, a sedentary lifestyle, and social and mental stress. Obesity or being overweight can increase the risk of heart disease. Manage diabetes.
years, p = 0.008) and had enrollment diagnoses of obesity [BMI ≥ 30 kg/m2; 80% (12/15) vs 49% (598/1230), p = 0.016] and hyperlipidemia [87% (13/15) vs 58% (713/1230), p = 0.025]. Sex, former/current tobacco use, and known diagnoses of hypertension and diabetes mellitus did not differ. years vs 61.2 ± 10.6
November is National Diabetes Month , and with the increasing overlap between type 2 diabetes (T2D) and metabolic dysfunction-associated steatohepatitis (MASH) , it’s critical to focus on integrating liver health into the management of cardiometabolic patients.
BackgroundThe weight adjusted waist index (WWI) represents a novel indicator for assessing central obesity. and the ROC analysis results showed that the discriminatory power of WWI for CHD was superior to that of body mass index (BMI) and WC. Additionally, RCS analysis indicated a linear relationship between WWI and CHD.
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