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Sodium-glucose cotransporter 2 inhibitors and cardiovascular events among patients with type 2 diabetes and low-to-normal body mass index: a nationwide cohort study

Cardiovascular Diabetology

Patients with low-to-normal body mass index (BMI; < 25.0 kg/m2) were underrepresented in major randomized controlled trials on sodium-glucose cotransporter 2 (SGLT2) inhibitors for type 2 diabetes. The present st.

Diabetes 120
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How To Reverse Diabetes.

Dr. Paddy Barrett

In the US, over 45% of the population has either diabetes or pre-diabetes 1. The absolute majority of those with diabetes have type 2 diabetes, which is usually associated with excess visceral fat and poor cardiometabolic health. Because a diagnosis of diabetes is very likely to shorten your life. Pre-Diabetes.

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Tirzepatide Sheds Pounds in Chinese Adults With BMI as Low as 24

Med Page Today

In the study of 210 adults without diabetes, participants on tirzepatide. (MedPage Today) -- Tirzepatide (Zepbound) was effective at reducing body weight in Chinese adults with lower cutoffs for overweight or obesity, the SURMOUNT-CN trial reported.

BMI 104
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BMI variability and cardiovascular outcomes within clinical trial and real-world environments in type 2 diabetes: an IMI2 SOPHIA study

Cardiovascular Diabetology

BMI variability has been associated with increased cardiovascular disease risk in individuals with type 2 diabetes, however comparison between clinical studies and real-world observational evidence has been la.

BMI 59
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Maternal Height, Pre-Pregnancy BMI, Weight Gain Affect Adverse Pregnancy Events

HCPLive

Maternal height is linked to specific adverse pregnancy events in women with gestational diabetes mellitus, according to a new study. The investigators found shorter women had higher rates of low birth rate and primary c-sections, but taller women had higher rates of abnormal neonatal ponderal index, postpartum hemorrhage, and macrosomia.

BMI 59
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Red Meat and Diabetes: Untangling Causation from Correlation

Physiologically Speaking

In this week's post, we take a deep dive into the latest study showing that red meat intake is associated with type 2 diabetes…one that caused quite a stir in the media. More meat, more diabetes? Model 3 is nearly identical to model 2, but omits the adjustment for BMI. This is where the authors make a very critical move.

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GLP-1 Receptor Agonists Along With SGLT2 Inhibitors for HFpEF

American College of Cardiology

What is the incremental benefit in patients with heart failure and preserved ejection fraction (HFpEF) of glucagon-like peptide-1 receptor agonists (GLP-1 RA) combined with sodium-glucose cotransporter 2 inhibitors (SGLT2i) in patients with type 2 diabetes mellitus (T2DM) and body mass index (BMI) ≥27?