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Abstract Background N-terminal pro-B-type natriuretic peptide (NT-proBNP) concentrations are lower in patients with obesity. The interaction between body mass index (BMI) and NT-proBNP with respect to heart failure (HF) risk remains incompletely defined. pg/mL lower NT-proBNP per 1 kg/m 2 higher BMI; p<0.001). vs. 0.6%, 1.3%
Previous studies have associated obesity with negative changes in the right ventricle using imaging techniques. However, the connection between obesity and more direct measures of right ventricle function, particularly those reflecting hemodynamic consequences, have been unclear. Original article: Circ Heart Fail. 2023;16:e010524.
When it comes to cardiovascular disease, two of the biggest risk factors we must consider are: ApoB concentration - A measure of the number of circulating lipid particles. Not all circulating ApoB particles will transition across the artery wall, but some will. Trends in the number of obese and severely obese people by region.
Can you please explain the concept of an obesity paradox? Salvatore Carbone, PhD: First, I’d like to point out that obesity is a major risk factor for cardiometabolic disease. 2, 3] This association is more pronounced for those with class I obesity, which is a body mass index (BMI) between 30-35 kg/m2.
Circulation, Volume 150, Issue Suppl_1 , Page A4125500-A4125500, November 12, 2024. Background:Impaired left atrial (LA) function is observed in obese patients, however, there is little information on when LA dysfunction begins to appear. kg/m2; obese (n=15), ≧20 kg/m2.
Circulation, Volume 150, Issue Suppl_1 , Page A4144999-A4144999, November 12, 2024. Obesity is associated with increased cardiovascular risk and adverse cardiac changes such as left ventricular hypertrophy (LVH) and in TOF higher body mass index (BMI) contributed to increase risk. mL/m2, p=0.04; RVEDVi 157.4±21.5 vs RVEDV 297.6±56.6
Circulation, Ahead of Print. Optimal NT-proBNP cut points for HFpEF rule out (optimizing sensitivity) and rule in (optimizing specificity) were derived and tested, stratified by obesity and atrial fibrillation. Current consensus age- and BMI-stratified rule-in thresholds demonstrated only 65% specificity (95% CI, 57%72%).
Circulation, Ahead of Print. Background: Patients with heart failure, a preserved ejection fraction (HFpEF), and obesity have significant disability and suffer frequent exacerbations of heart failure. n=393) were female; BMI 38.26.7kg/m2, KCCQ-CSS 53.518.5,
Circulation, Volume 150, Issue Suppl_1 , Page A4146967-A4146967, November 12, 2024. Overall BMI was normal, however 17% (5 of 30) were overweight or obese (Table 1).The Objectives:Physically active lifestyles are important for patients with congenital heart disease, including Fontan. The less active Fontan had higher fat% (24.8±8.7
Circulation, Ahead of Print. Background:Patients with heart failure (HF) with preserved ejection fraction (HFpEF) and obesity experience high burden of symptoms and functional impairment, and a poor quality of life. In the STEP-HFpEF trial, once-weekly semaglutide 2.4 mg or placebo for 52 weeks. across domains;P<0.05
Circulation, Volume 150, Issue Suppl_1 , Page A4142589-A4142589, November 12, 2024. Based on the finetuned NN, we predicted risk markers within an independent cohort of 48,376 patients with a history of T2D, ASCVD, or obesity and emulated a target trial to evaluate the subclinical effect of GLP1RA. Hispanic, 9.6% Asian, and 4.6%
Older adults with obesity and metabolic syndrome may have decreased elimination of the xylitol metabolite xylose, which may explain the higher observed risk of thrombosis and stroke in older adults who consume foods with sugar alcohols. The mean BMI was 35.2 kg/m2, HbA1c was 5.9% 0.4,
Circulation, Volume 150, Issue Suppl_1 , Page A4142557-A4142557, November 12, 2024. A physical examination was performed, heart rate was assessed, blood pressure was measured according to Korotkov method, body mass index (BMI) was calculated. Background:In Central Asia, hypertension accounts for 14.5% Heart rate in group 1 was 89.8±12.2
Circulation, Volume 150, Issue Suppl_1 , Page A4123899-A4123899, November 12, 2024. The mean BMI was 27.9 kg/m2, with 4 classified as obese. Four patients with significant structural heart disease were excluded, resulting in a final sample size of 14. Of these, 9 (64%) were female with a mean age of 59.6,
Food and Drug Administration ( FDA ) has approved an additional indication for Wegovy ( semaglutide ) to reduce the risk of major cardiovascular events such as death, heart attack, or stroke in adults with known heart disease and with either obesity or overweight along with a reduced calorie diet and increased physical activity.
Circulation, Volume 150, Issue Suppl_1 , Page A4118122-A4118122, November 12, 2024. Patients studied were older (68 years old), white (90%), obese (average BMI 34 kg/m2) individuals with an average LVEF of 61%. Baseline demographics are shown in Table 1.
However, recent studies have observed that people below 40 are also experiencing heart attacks due to high blood pressure, cholesterol, diabetes, smoking, obesity, a sedentary lifestyle, and social and mental stress. This indicates that restoring normal blood circulation as quickly as possible will result in less damage.
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