Dr. Paddy Barrett

APRIL 4, 2025

Do you use advanced cholesterol testing? List vital measurements—eg Weight, Height, BMI etc. This is all about understanding whether a 'risk factor,’ e.g. High LDL-C cholesterol, has translated into significant ‘disease,’ e.g. coronary artery disease. How do you know they are the right doctor?

Blood Pressure 84

Blood Pressure Exercise Heart Disease Cholesterol 84

Physiologically Speaking

JANUARY 12, 2024

A few biochemical measures were associated with biological age: higher triglycerides predicted faster age acceleration while higher HDL cholesterol predicted slower age acceleration. However, body mass index (BMI) was not associated with biological age acceleration. vitamin C , Beta-carotene ) — eat your fruits and veggies!

Physiology 124

Physiology BMI Exercise Diet 124

Physiologically Speaking

JANUARY 5, 2024

Furthermore, BMI and waist circumference decreased in the HIIT group — changes were larger than that of the control group in which none of these outcomes improved. Regarding blood lipids, there were no changes total cholesterol, HDL cholesterol, LDL cholesterol, triglycerides, or apolipoprotein A1 (ApoA1) or apolipoprotein-B (ApoB).

Plaque 119

Plaque Physiology Exercise Cholesterol 119

Stroke Journal

FEBRUARY 1, 2024

Body mass index (BMI) is a widely available marker of nutrition status, however studies on BMI and post-ICH outcomes are limited and have conflicting results. Patients were divided into underweight, normal weight, overweight, and obese according to World Health Organization BMI criteria. 7.34) and lobar (OR 3.15, 95% CI 1.67-5.94)

Hemorrhage 40

Hemorrhage BMI Outcomes Coronary Artery Disease 40

Frontiers in Cardiovascular Medicine

MARCH 4, 2024

There were no significant difference between the two groups in terms of age, gender, body mass index (BMI), left ventricular ejection fraction(LVEF), low-density lipoprotein cholesterol(LDL-C),cardiovascular risk factors. In Group A, no significant differences in CPET indices were observed before and after the intervention.

Exercise 64

Exercise Cardiac Rehabilitation Quality of Life BMI 64

Cardiology Update

JANUARY 24, 2024

Metabolic risks, including high systolic blood pressure, high LDL cholesterol, high BMI, high fasting plasma glucose, and kidney dysfunction, contribute substantially to age-standardized CVD disability-adjusted life years (DALYs).

Cardiovascular Disease 119

Cardiovascular Disease Research Blood Pressure Public Health 119

Stroke Journal

FEBRUARY 1, 2024

It is currently unknown if these associations are confounded by pleiotropic effects of the instrumental variables (IV) on cardiovascular disease (CVD) risk factors, such as low-density lipoprotein cholesterol (LDL), diastolic blood pressure (DBP), and body mass index (BMI). 0.96]), or BMI (TSAT: 1.18 [1.04-1.34];

BMI 40

BMI Risk Factors Stroke Strokes 40

Cardiometabolic Health Congress

JANUARY 3, 2024

Tirzepatide In November of 2023, the FDA approved tirzepatide (Zepbound) for chronic weight management in adults with obesity, or who are overweight with at least one weight-related condition, such as high blood pressure, type 2 diabetes, or high cholesterol.

Obesity 97

Obesity Diabetes Blood Pressure BMI 97

MIBHS

OCTOBER 31, 2023

Limit your intake of saturated and trans fats, as they can raise cholesterol levels and increase the risk of heart disease. Calculate your body mass index (BMI) to determine whether you are within a healthy weight range for your height. They can assess your blood pressure, cholesterol levels, and other risk factors.

Blood Pressure 52

Blood Pressure Heart Disease Diet Risk Factors 52

Physiologically Speaking

FEBRUARY 23, 2024

Specifically, eating a meal containing 25 grams of protein or more activates the mammalian target of rapamycin complex 1 (mTORC1) and inhibits autophagy in immune cells known as macrophages, which promote the buildup of plaque and cholesterol in arteries, a process known as atherosclerosis. Does this same mechanism exist in humans?

Physiology 111

Physiology Atherosclerosis Diet Cardiovascular Disease 111

Physiologically Speaking

DECEMBER 1, 2023

Results 📊 Body mass, BMI, and fat-free mass declined during bed rest, while relative fat mass increased — body composition got much worse. Plasma insulin and triglycerides increased, while serum total and high-density lipoprotein (HDL) cholesterol decreased.

Exercise 98

Exercise Physiology BMI Cholesterol 98

Stroke Journal

JANUARY 30, 2025

The mean BMI was 35.2 fasting blood glucose was 103 13 mg/dL, HDL cholesterol was 49 10 mg/dL, and triglycerides were 173 63 mg/dL. kg/m2, HbA1c was 5.9% 0.4, Xylose concentrations were inversely correlated with six miRs (miR-15b, miR-151a-3p, miR-151a-5p, miR-151b, miR-24-3p, and miR-27a-3p).

Thrombosis 40

Thrombosis Obesity Stroke Strokes 40

Dr. Paddy Barrett

JANUARY 16, 2024

The 8 factors include: Nutrition - Mediterranean Eating Pattern Score Physical Activity - >150 mins Mod-Vigourous Weekly Activity = Ideal Smoking Status - Never = Ideal Sleep - >7 hours per night = Ideal BMI - <25 = Ideal Non-HDL Cholesterol - <3.36mmol (130 mg/dl ) = Ideal Blood Glucose - HBA1c < 39 = Ideal Blood Pressure - <120/<80 (..)

Cancer 94

Cancer Dementia Diabetes Cardiovascular Disease 94

Dr. Paddy Barrett

FEBRUARY 13, 2024

Even in diabetics of normal weight (BMI<27), weight loss can reverse diabetes 2. Be satiating Low in sugar In a Carbohydrate/Fat Balance that suits your preference and doesn’t drive your LDL cholesterol through the roof. Mostly, it is about weight loss, specifically visceral fat loss and the reversal of insulin resistance.

Diet 103

Diet Diabetes Exercise Kidney Disease 103

Dr. Paddy Barrett

AUGUST 16, 2024

Falling into the class of obesity with a BMI of greater than 30 makes this more likely, but so also does having excess visceral fat deposition with significant metabolic consequences at a BMI less than 30. The distinction here is the metabolic consequences of excess fat causing a health risk rather than focusing on the BMI cutoff.

Obesity 52

Obesity Blood Pressure Diet Exercise 52

Dr. Paddy Barrett

AUGUST 29, 2023

Share JUPITER In 2008 a landmark paper was published showing that in people without cardiovascular disease and relatively normal LDL-cholesterol (<3.4 Because of the increased risk, I am also quicker to introduce non-statin-based cholesterol-lowering agents such as ezetimibe, bempedoic acid, PCSK9 inhibitors or inclisiran when available.

Diabetes 52

Diabetes Risk Factors Heart attacks Heart Attack 52

Physiologically Speaking

DECEMBER 15, 2023

Specifically: - HDL cholesterol increases by 2–12 mg/dL - Total cholesterol decreases by 8 mg/dL - Triglycerides decrease by 7–13 mg/dL - LDL cholesterol may decrease by 10–13 mg/dL in adults at high cardiometabolic risk Weight and body composition Here’s where resistance exercise shines.

Physiology 52

Physiology Exercise Blood Pressure Risk Factors 52

Physiologically Speaking

DECEMBER 15, 2023

Specifically: - HDL cholesterol increases by 2–12 mg/dL - Total cholesterol decreases by 8 mg/dL - Triglycerides decrease by 7–13 mg/dL - LDL cholesterol may decrease by 10–13 mg/dL in adults at high cardiometabolic risk Weight and body composition Here’s where resistance exercise shines.

Physiology 52

Physiology Exercise Blood Pressure Risk Factors 52

Dr. Paddy Barrett

OCTOBER 31, 2023

A healthy lifestyle, in this instance, is defined by a combination of: BMI Nutrition Smoking Status Activity Levels Blood Pressure Diabetes Status Cholesterol Levels All of which are highly modifiable.

Coronary Artery Disease 52

Coronary Artery Disease Heart Disease Atherosclerosis Cardiovascular Disease 52

Physiologically Speaking

DECEMBER 22, 2023

Clinically, about 1/3 of adults have metabolic syndrome — a cluster of conditions including abdominal obesity, high blood pressure, high blood glucose, high triglycerides, and low HDL cholesterol. link] Of course, diet is an important component of metabolic health, but exercise also plays an indispensable role.

Exercise 52

Exercise Physiology Blood Pressure Cholesterol 52

Physiologically Speaking

DECEMBER 22, 2023

Clinically, about 1/3 of adults have metabolic syndrome — a cluster of conditions including abdominal obesity, high blood pressure, high blood glucose, high triglycerides, and low HDL cholesterol. link] Of course, diet is an important component of metabolic health, but exercise also plays an indispensable role.

Exercise 52

Exercise Physiology Blood Pressure Cholesterol 52

Physiologically Speaking

JANUARY 26, 2024

Strengthening these results (in my opinion) is the baseline health status of the participants: they reported generally few cognitive complaints, had only a slightly overweight body mass index (BMI), and other than hypertension and the use of cholesterol-lowering medications, had a low prevalence of diseases and other risk factors.

Physiology 52

Physiology Diet Cardiovascular Disease BMI 52

DAIC

FEBRUARY 1, 2024

QRISK incorporates factors such as blood pressure, cholesterol, BMI, smoking status, age, sex, and family history to estimate risk. Risk assessment is essential to identify the patients who would benefit from preventative measures, such as lifestyle changes, extra screening, or treatments, for example, statins to lower cholesterol.

Cardiovascular Disease 110

Cardiovascular Disease Risk Factors Best Practices Cholesterol 110

Frontiers in Cardiovascular Medicine

FEBRUARY 7, 2024

The primary outcomes encompassed cardio-metabolic parameters, including body mass index (BMI), body fat mass (BFM), systolic and diastolic blood pressure, triglycerides, HDL and LDL cholesterol, C-reactive protein, and the Ankle-Brachial Pressure Index (ABPI).

Atherosclerosis 69

Atherosclerosis Cerebrovascular Disease Blood Pressure BMI 69

Wellnest

JULY 19, 2023

The accumulation of cholesterol, foam cells, fibrous tissue, and calcium mainly causes the narrowing of coronary arteries. However, recent studies have observed that people below 40 are also experiencing heart attacks due to high blood pressure, cholesterol, diabetes, smoking, obesity, a sedentary lifestyle, and social and mental stress.

Heart attacks 52

Heart attacks Heart Attack Blood Pressure Myocardial Infarction 52

DAIC

MARCH 8, 2024

The estimated relative risk reduction of MACE was 20% vs placebo (HR 0.80 [95% CI: 0.72, 0.90] p 1,2 The reduction of MACE with Wegovy was not impacted by age, sex, race, ethnicity, baseline BMI, or level of renal function impairment. in patients randomized to Wegovy 2.4 mg and 36.4% of patients receiving placebo. 10,11 In the U.S.,

Obesity 111

Obesity Heart Disease Heart attacks Heart Attack 111

Stroke Journal

JANUARY 30, 2025

These involve managing and controlling risk factors for recurrence, such as blood pressure, body mass index (BMI), low-density lipoprotein (LDL) cholesterol, glycated hemoglobin (HbA1c), smoking, alcohol consumption and physical activity. In stroke survivors, adherence to blood pressure (+1.4%

Blood Pressure 40

Blood Pressure Stroke Strokes BMI 40

Stroke Journal

FEBRUARY 1, 2024

Model covariates included sex, age, marital status, household size, household income, education, race/ethnicity, insurance, body mass index (BMI), and an indicator of the condition of interest. SD=1.5), high cholesterol (-5.7, SD=21.8), followed by other (i.e., SD=21.0), Hispanics (59.3, SD=21.6), and Blacks (56.2, and CVD (-6.3,

Cholesterol 40

Cholesterol Education Blood Pressure BMI 40

Stroke Journal

FEBRUARY 1, 2024

Body mass index (BMI) and diabetes mellitus are independent risk factors for ICAS. Hypertension is an independent risk factor for incident lacunes and CMB, whereas WMH progression is primarily affected by BMI. Higher LDL cholesterol level independently protects against WMH progression. Results:Of the 756 participants (aged 53.7±8.0

Stenosis 40

Stenosis BMI Risk Factors Cholesterol 40

Stroke Journal

JANUARY 30, 2025

Results:Among the 9,444 participants included, the mean age was 57 (5.7 SD), and 43.2% were men.

Atherosclerosis 40

Atherosclerosis Stroke Strokes Atrial Fibrillation 40

Frontiers in Cardiovascular Medicine

DECEMBER 18, 2024

This study aimed to investigate the association of plasma lipid concentrations with the prevalence of OSA among US adults, with an additional examination of the mediating effect of body mass index (BMI).MethodsThis However, total cholesterol (TC) and high-density lipoprotein cholesterol (HDL-C) were not associated with OSA.

BMI 52

BMI Cholesterol Research 52

Frontiers in Cardiovascular Medicine

NOVEMBER 21, 2024

The incidence of major adverse cardiovascular events and unplanned readmission at 6 months after discharge between the two groups was lower in the observation group than in the control group, and the difference was statistically significant (P < 0.05).ConclusionThe

Exercise 59

Exercise Coronary Artery Disease Cholesterol BMI 59