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9, 2025 Gender-based racism through microaggressions may be linked to higher bloodpressure postpartum and beyond, according to new research published in Hypertension , a peer-reviewed journal of the American Heart Association. Between these two groups, there was an average top number bloodpressure difference of 7.55
Welcome to the Physiology Friday newsletter. Physiologically Speaking is a reader-supported publication. When we don’t get enough sleep, our physiology suffers—insulin sensitivity tanks, cognitive function wanes, and physical performance is drastically impaired. I know I have (new dad here). and woke up at 7 a.m. (8
Welcome to the Physiology Friday newsletter. Physiologically Speaking is a reader-supported publication. When we are standing up or walking around (ambulating), our muscles contract to maintain posture and blood flow increases to meet the metabolic demands of the muscles.
However, according to new research published in the American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, breathing through the nose leads to several benefits, including lower bloodpressure and other factors that could predict heart disease risk. More than half of adults living in the U.S.
Our body’s physiological processes oscillate on a 24-hour cycle known as the circadian rhythm. Circadian rhythms in bloodpressure and heart rate, among other functions, are crucial for cardiovascular health and preventing cardiovascular disease. In general, light exposure increases nighttime bloodpressure and heart rate.
Aerobic training is known to regulate bloodpressure more effectively when practiced in the evening than in the morning. The study is published in The Journal of Physiology.
BACKGROUND:Circulating proteins in blood are involved in various physiological processes, but their contributions to bloodpressure regulation remain partially understood. Colocalization analyses were then used to investigate whether the circulating proteins and bloodpressure traits shared causal genetic variants.
Many times , an Innocuous question poses a real challenge, to our life time understanding of circulatory physiology. This again has more dynamic and interesting changes especially in the diastolic BP.Read Guyton’s physiology or the good old Rushmer’s hemodynamics monograph, linked in this site elsewhere. Reference 1.Wahba
Simultaneously, physiological responses essential for stress adaptation are triggered in the body. Cardiovascular regulation, including changes in bloodpressure and heart rate, is a critical stress response. Under stress, animals change their behavior, such as through "fight or flight" or "freezing" response.
Obstructive sleep apnea carries significant physiological and psychological impacts on health. The key secondary objective is to quantify bloodpressure throughout the night using continuous BP monitoring during performance of a standard sleep study without the benefit of CPAP.
Welcome to the Physiology Friday newsletter. Physiologically Speaking is a reader-supported publication. Clinically, about 1/3 of adults have metabolic syndrome — a cluster of conditions including abdominal obesity, high bloodpressure, high blood glucose, high triglycerides, and low HDL cholesterol.
Welcome to the Physiology Friday newsletter. Physiologically Speaking is a reader-supported publication. Clinically, about 1/3 of adults have metabolic syndrome — a cluster of conditions including abdominal obesity, high bloodpressure, high blood glucose, high triglycerides, and low HDL cholesterol.
This may be partly due to the disproportionate incidence of salt sensitivity of bloodpressure in Black people, a cardiovascular risk factor that is independent of bloodpressure and has no proven therapy.
Welcome to the Physiology Friday newsletter. Physiologically Speaking is a reader-supported publication. Resting metabolic rate, overnight heart rate, and overnight systolic and diastolic bloodpressure were unaltered by carbohydrate or sugar restriction. No surprises here. That’s a sweet conclusion.
BACKGROUND:Potassium (K+)-deficient diets, typical of modern processed foods, increase bloodpressure (BP) and NaCl sensitivity. Hypertension, Ahead of Print.
Introduction:Autoregulation-guided bloodpressure (BP) management offers a promising alternative to targeting fixed BP thresholds after acute ischemic stroke. Stroke, Volume 56, Issue Suppl_1 , Page A117-A117, February 1, 2025.
Exercise testing can serve as a powerful physiologic probe to unmask subclinical cardiovascular abnormalities well before disease onset. For example, bloodpressure changes during exercise (EBP) can reveal a latent tendency toward future development of hypertension.
It encompasses devices designed to mechanically unload the failing heart and augment cardiac output in the setting of dangerously low bloodpressure, providing a bridge to recovery over a period of hours to days. MCS is one of the fastest growing markets in interventional cardiology. Magenta Medical Ltd.
Several microRNAs (miRNAs) strongly influence bloodpressure and the development of hypertension by modulating vascular, renal, and other physiological mechanisms. In addition, miRNAs may contribute to the genetic regulation of bloodpressure.
Introduction:Immediately after AIS onset, bloodpressure variability (BPV) arises as the result of a complex interplay between brain and systemic physiological hemodynamic responses. Stroke, Volume 55, Issue Suppl_1 , Page ATP190-ATP190, February 1, 2024.
Welcome to the Physiology Friday newsletter. Physiologically Speaking is a reader-supported publication. Prolonged bouts of sitting negatively contribute to health by causing endothelial dysfunction, bloodpressure elevations, and glucose dysregulation.
Welcome to the Physiology Friday newsletter. Physiologically Speaking is a reader-supported publication. Overnight, brain activity and other physiological metrics were measured using a technique known as polysomnography (PSG). During REM, our brain activity, breathing, and heart rate and bloodpressure increase.
Welcome to the Physiology Friday newsletter. Physiologically Speaking is a reader-supported publication. For example, bloodpressure and cortisol rise in the morning upon awakening to prepare us for the day that lies ahead. Journal of Applied Physiology. That’s what a new study suggests. 00632.2023.
BACKGROUND:Small arteries exhibit resting tone, a partially contracted state that maintains arterial bloodpressure. Perivascular adipose tissue (PVAT) has been shown to exert anticontractile effects on the blood vessels. This effect relaxes small arteries and regulates bloodpressure. Hypertension, Ahead of Print.
Despite a major research focus on organ systems and these effector mechanisms causing NaCl-induced increases in arterial bloodpressure, relatively less research has been directed at elucidating how NaCl is sensed by various tissues to elicit these downstream effects.
The Role of Wearable Technology in Heart Health Wearable tech is designed to monitor physiological data and provide actionable insights to users. For heart health, these devices use advanced sensors to track metrics like heart rate, blood oxygen levels, and even irregular heart rhythms.
Moreover, despite the availability of antihypertensive medications for the management of bloodpressure, treatments that address the full spectrum of the pathophysiological defects underpinning hypertension remain to be identified. Nevertheless, the pathogenesis of hypertension has not been fully elucidated.
At age 32 years, participants underwent a physiological assessment, and CVH was estimated using Life's Essential 8 metrics: body mass index, bloodpressure, cholesterol, glycated hemoglobin, sleep, smoking, and physical activity (diet not available).
Serotonin (5-hydroxytryptamine, 5-HT) at low plasma concentrations reduces bloodpressure and dilates some skeletal muscle arterioles in the rat. We hypothesized that the 5-HT7 receptor is essential for both 5-HT-induced changes in bloodpressure and skeletal muscle arteriolar function. All rights reserved.
Background The relationship between speckle tracking assessed global longitudinal strain (GLS) and Doppler-based echocardiography with basic physiological markers of cardiac function derived from pressure-volume loops is poorly elucidated. and r 2 =0.49, respectively).
Susceptibility MMD genes, including ring finger protein 213/mysterin andGUCY1A3, have also been linked to extracranial vascular disease and increased systolic bloodpressure. Bloodpressure measurements and antihypertensive agent use were recorded pre‐ and postoperatively. After a mean follow‐up of 34.3±18.1
A complex network of genetic, epigenetic, physiological, and environmental components regulates bloodpressure (BP), and any dysregulation of this network may result in hypertension. Hypertension, Ahead of Print. Essential hypertension, a multifaceted disorder, is a worldwide health problem.
However, prolonged exposure to stress can lead to persistently high levels of these hormones, contributing to increased heart rate, elevated bloodpressure, and inflammation, all of which raise the risk of heart disease. People with anxiety often experience elevated heart rates and increased bloodpressure.
It is a physiological adaptation helping athletes perform physical tasks better than non-athletes. Systemic vascular resistance falls, but slight to moderate increase in bloodpressure can occur due to the increased cardiac output. The upper limit of physiologic cardiac hypertrophy in highly trained elite athletes.
These data suggest that, during physiological stress, sympathetic reactivity is intact, but the peripheral pathway for sympathetic vasoconstriction may be impaired in HFpEF. Furthermore, patients had preserved sympathetic reactivity but attenuated diastolic BP responses during the cold pressor test.
The hemodynamic of the Giraffe’s vascular system is a good physiologic model of circulation, that defy gravity. Maloney, Duncan Mitchell The origin of mean arterial and jugular venous bloodpressures in giraffes The Journal of Experimental Biology 209, 2515-2524 2.Aalkjær Reference 1. Graham Mitchell Shane K.
And, the drug does provide physiologic benefits for a patient with an acute cardiac event ( ie, it helps to relieve anxiety as well as pain — which may decrease activation of autonomic nervous system activity — often resulting in reduced heart rate, bloodpressure, venous return and myocardial oxygen demand — Murphy et al: StatPearls, 2023 ).
Nicotine and other harmful substances present in tobacco can lead to constriction of blood vessels, an increase in heart rate, and elevated bloodpressure. Chronic stress triggers physiological responses that can adversely affect the cardiovascular system.
Physiologically Speaking is a reader-supported publication. It also supports blood vessel health and may reduce bloodpressure. In this post, we’ll take a deep dive into the science of fasting and discuss whether time-restricted eating is “better” than calorie counting for health and weight loss.
By analyzing the same, it can accurately deduct the person’s age, gender, bloodpressure, and smoking status. Using this data; the AI can further predict the patient’s cardiovascular disease risk using optic disks and blood vessels. The deep learning algorithm scans the patient’s rear interior wall of the eye (the fundus).
AV synchrony and physiologic ventricular depolarization the hemodynamics improved. Lowering the back up rate (LRL) of the ICD/pacer allowed for an intrinsic rhythm with physiologic AV conduction and normal AV synchrony with resultant increase in stroke volume and cardiac outpt.
The initial bloodpressure was 80/palp with a heart rate of 104, respirations 20, oxygen saturations of 94% and a finger stick blood glucose of 268. In addition, the patient received 750 mL of fluid resuscitation with transient improvement of bloodpressure.
He is placed on heparin drip, he will have IV beta-blocker and oral beta blocker for heart rate control and bloodpressure management. The fact that it was delayed until late the next day is further indication that the treating team failed to appreciate the physiologic sequence of events associated with evolving OMI.
Welcome to the Physiology Friday newsletter. Physiologically Speaking is a reader-supported publication. What physiological mechanisms make moderate to high levels of activity so favorable, especially in our modern environment? This week, I’m sharing one of my favorite articles I’ve ever written.
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