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A smartphone-guided secondary prevention digital health application reduces systolic blood pressure in patients with chronic coronary syndrome and insufficient blood pressure control

Frontiers in Cardiovascular Medicine

Several modifiable risk factors, including increased blood pressure (BP), significantly contribute to cardiovascular risk in CCS. Therefore, optimal secondary prevention includes managing BP through lifestyle changes and pharmacological therapy.

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Endothelial lipid droplets suppress eNOS to link high fat consumption to blood pressure elevation

Journal of Clinical Investigation - Cardiology

How these conditions are linked mechanistically remains unclear, especially two of these: obesity and elevated blood pressure. Pharmacological prevention of lipid droplet formation reverses the suppression of NO production in cell culture and in vivo and blunts blood pressure elevation in response to a high-fat diet.

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Integrated meta-analysis and network pharmacology analysis: evaluation of Zhigancao decoction as treatment for diabetic cardiomyopathy

Frontiers in Cardiovascular Medicine

ZGCD not only significantly reduces blood pressure, but also enhances cardiac function while producing fewer adverse effects. Meanwhile, the utilization of ZGCD during intervention was more effective in reducing SBP, and DBP. In addition, the ZGCD showed potential in reducing the occurrence of adverse events.

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The effect of enhanced external counterpulsation on anxiety and depression in patients with paroxysmal atrial fibrillation: a randomized controlled trial

Frontiers in Cardiovascular Medicine

The control group received conventional antiarrhythmic therapy with -blockers or propafenone, and the EECP group underwent EECP therapy in conjunction with pharmacological treatment. The EECP therapy protocol consisted of 60-min sessions, conducted five times per week over a four-week period.

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Therapeutic effect and potential mechanism of Fufang Danshen dripping pills for stable coronary heart disease: a randomized controlled trial

Frontiers in Cardiovascular Medicine

Furthermore, we utilized mass spectrometry analysis, network pharmacology, and lipidomics to predict the potential mechanisms of FFDS in the treatment of SCHD.ResultsFollowing treatment, FFDS demonstrated significant improvements in serum triglyceride levels (P=0.013) and a reduction in the frequency of angina episodes (P=0.021).

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Weight loss from surgery or drug therapy reduces blood pressure

Nature Reviews - Cardiology

Nature Reviews Cardiology, Published online: 19 February 2024; doi:10.1038/s41569-024-01000-6 Two studies indicate that a reduction in body mass index as a result of either bariatric surgery or pharmacological therapy is associated with a blood pressure-lowering effect.

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Pyridostigmine in the management of orthostatic hypotension: a systematic review and meta-analysis

Open Heart

Background Current pharmacological approaches for the treatment of orthostatic hypotension (OH) may detrimentally affect supine blood pressure (BP). This side effect is often unacceptable and limits the utility of medical management.