Cardiology Update

JULY 22, 2024

A study published in The Lancet reveals that targeting a systolic blood pressure of less than 120 mm Hg significantly reduces cardiovascular events in high-risk patients, compared to the standard target of less than 140 mm Hg. Key Findings – Blood Pressure Levels: The mean systolic blood pressure during follow-up was 119.1

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DAIC

MAY 14, 2024

UVA Health's Karen Johnston, MD, the SHINE trial leader, was pleased to see the new insights into best practices for stroke care. These data from the SHINE trial continue to inform the national stroke community about potential approaches to treating hyperglycemic stroke patients to assure better outcomes,” she said.

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Hypertension Journal

JANUARY 2, 2024

BACKGROUND:Data on systolic blood pressure (SBP) trajectories in the first 24 hours after endovascular thrombectomy (EVT) in acute ischemic stroke are limited. 2.31]), and worse functional outcomes (adjusted common odds ratio,1.92 [95% CI, 1.47–2.50]).CONCLUSIONS:Patients 2.59]), mortality (aOR, 1.75 [95% CI, 1.21–2.53),

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Frontiers in Cardiovascular Medicine

JANUARY 22, 2024

Introduction Compared with first-line antihypertensives, beta-blockers (BB) have been reported to lower the central aortic blood pressure suboptimally and are associated with increased stroke risk. Second- or third-generation beta-blockers reduced the mean arterial pressure by 1.75 mmHg [95% confidence interval (CI):1.16–2.33;

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Blood Pressure Hypertension Myocardial Infarction Cardiovascular Disease 64

Stroke Journal

FEBRUARY 27, 2024

Stroke, Ahead of Print. The primary outcome was functional status measured by the modified Rankin Scale at 90 to 180 days. Earlier SBP control was associated with better functional outcomes (modified Rankin Scale score, 3–6; odds ratio, 0.98 [95% CI, 0.97–0.99]) SD, 13.0], 2120 [36.8%] females) were included in analyses.

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Hypertension Journal

JANUARY 2, 2024

Using Cox proportional hazards regression, we tested interactions between history of cancer and intensive blood pressure control on major cardiovascular outcomes.RESULTS:The study included a total of 9336 patients, with a mean age of 67.9±9.4 years, 561 primary cardiovascular outcomes were observed. Over a median follow-up of 3.2

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Medical Xpress - Cardiology

MARCH 26, 2024

Adults younger than 35 to 45 years old may have a higher risk of developing a stroke from nontraditional risk factors such as migraines than from traditional risks like high blood pressure. That's according to new research published today in Circulation: Cardiovascular Quality and Outcomes.

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Med Page Today

MAY 16, 2024

(MedPage Today) -- Bringing blood pressure under control in the ambulance didn't improve stroke outcomes in an unselected population, the China-based INTERACT 4 trial showed. Functional outcome measured by the modified Rankin Scale was no better.

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Stroke: Vascular and Interventional Neurology

FEBRUARY 26, 2024

Stroke: Vascular and Interventional Neurology, Ahead of Print. We included the outcomes of our trial in an aggregate data meta‐analysis of randomized‐controlled clinical trials evaluating the utility of BP control after successful EVT. participants/month).

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Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWP210-AWP210, February 1, 2024. Background:Optimal Blood pressure management after thrombectomy for acute ischemic stroke and its association with clinical outcomes remains unclear. There were comparable rates of sICH (OR 1.12, 95% CI 0.75-1.67;

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DAIC

JANUARY 19, 2024

AVIM therapy is an investigational patented bioelectronic therapy, administered using a standard dual-chamber pacemaker, designed to immediately, substantially and persistently reduce blood pressure. This leaves a gap in the care of these patients and increases their risk for heart attack, stroke and heart failure progression.

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Pacemaker Hypertension Blood Pressure Kidney Disease 105

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWP282-AWP282, February 1, 2024. Background:While blood pressure variability (BPV) is associated with poor cardiovascular outcomes, the relationship between BPV obtained in a very short interval and stroke is unknown. Up to 5% (487 patients) had a history of stroke.

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Circulation

JANUARY 24, 2024

METHODS:The AHA, through its Epidemiology and Prevention Statistics Committee, continuously monitors and evaluates sources of data on heart disease and stroke in the United States and globally to provide the most current information available in the annual Statistical Update with review of published literature through the year before writing.

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Heart Disease Stroke Strokes Peripheral Arterial Disease 81

Hypertension Journal

OCTOBER 10, 2023

BACKGROUND:The STEP (Strategy of Blood Pressure Intervention in the Elderly Hypertensive Patients) trial demonstrated that intensive systolic blood pressure (SBP) lowering has cardiovascular benefits. CONCLUSIONS:The beneficial effects of intensive SBP lowering on cardiovascular outcomes were unaffected by baseline DBP.

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Hypertension Journal

JANUARY 4, 2024

Background:It remains unclear whether blood pressure (BP) genetic variants could modify the efficacy of immediate antihypertensive treatment after acute ischemic stroke. The primary outcome was a combination of death and major disability at 14 days or hospital discharge. for interaction). 1.26), 1.08 (0.80–1.44),

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DAIC

MAY 21, 2024

A new peer-reviewed study published in the Journal of the American Heart Association , JAHA, found that Hello Heart’s digital heart health program was associated with reductions in blood pressure (BP), total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), and weight. Of 102,475 participants, 49.1% were female.

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Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWP145-AWP145, February 1, 2024. Background:Blood pressure variability (BPV) during the first 24 hours following endovascular therapy is associated with poor functional outcome. Systolic and diastolic blood pressure were recorded at 1Hz.

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Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWMP104-AWMP104, February 1, 2024. Introduction:Social support plays a vital role in shaping health behaviors and may impact disease outcomes such as blood pressure (BP) control.

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Stroke: Vascular and Interventional Neurology

OCTOBER 4, 2023

Stroke: Vascular and Interventional Neurology, Volume 3, Issue 6 , November 1, 2023. BackgroundThe optimal blood pressure management strategy in patients undergoing endovascular therapy for acute ischemic stroke is unknown. The main outcome was the modified Rankin Scale score at 90 days. 7.23] versus 4.35 [3.73–5.1]

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Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWP196-AWP196, February 1, 2024. Background and Objectives:There are limited data evaluating the optimum blood pressure (BP) goal post mechanical thrombectomy (MT) and its effect on outcomes of patients with large vessel occlusions (LVO). 0.89, P < 0.001). 1.66, P =0.19).Conclusion:This

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Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page A137-A137, February 1, 2024. Introduction:Within 5 years of a stroke, approximately 25% of patients will have a recurrent event. Blood pressure (BP) reduction can reduce this risk; every 10 mmHg decrease in systolic BP is associated with a 20% risk reduction.

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Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page A51-A51, February 1, 2024. Background:Both increased blood pressure (BP) variability and impaired autoregulation have been linked to worse outcome after endovascular thrombectomy (EVT). p=0.028, Figure 1A). We found an interaction between BP variability and autoregulation (p=0.067).

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Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWP175-AWP175, February 1, 2024. Current guidelines for blood pressure (BP) management in patients with intracerebral hemorrhage (ICH) recommend acute lowering of systolic BP (SBP) to 140 mm Hg with a maintenance goal of 130 - 150 mm Hg. Results:2998 patients were found to have ICH.

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Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page A148-A148, February 1, 2024. Introduction:Prospective studies and secondary analyses from clinical trials have identified increased systolic blood pressure variability (SBPV) as a risk factor for poor outcomes.

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Open Heart

JUNE 24, 2022

Introduction COVID-19 may lead to long-term endothelial consequences including hypertension, stroke and myocardial infarction. A pilot study ‘COVID-19 blood pressure endothelium interaction study’, which found that patients with normal blood pressure (BP) at the time of hospital admission with COVID-19 showed an 8.6

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Heart BMJ

DECEMBER 20, 2023

Furthermore, coexistence of hypertension and AF mutually amplifies the risk of complications, such as heart failure and stroke. Hypertension is the single most important risk factor for development of atrial fibrillation (AF), which may be considered as a cardiac manifestation of hypertensive target organ damage.

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Open Heart

MARCH 1, 2024

Introduction Hypertension is the leading modifiable risk factor for cardiovascular disease and is implicated in half of all strokes and myocardial infarctions. One-third of the adults in Scotland have hypertension yet only a quarter of them have their blood pressure (BP) controlled to target (<140/90 mm Hg).

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Dr. Paddy Barrett

APRIL 5, 2024

Primary prevention is the management of the risk factors, e.g. high blood pressure, early in life to prevent complications of the condition, i.e. coronary artery disease. This refers to all the steps necessary to reduce the odds of a subsequent event, such as a second heart attack or stroke. Secondary prevention. N Engl J Med.

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DAIC

JUNE 25, 2024

HHNM will use the Allia IGS Pulse system in its cardiac electrophysiology (EP) lab to plan, guide and monitor the outcomes of electrophysiological procedures, such as cardiac ablations, cardiac catherizations, transcatheter aortic valve replacements, balloon and coronary angioplasties and more. “We It’s an honor to have the U.S.’s

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Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWMP78-AWMP78, February 1, 2024. Introduction:Mobile stroke units (MSUs) are an evolving means to expedited acute stroke management. Goal blood pressure was defined as systolic blood pressure &lt;160. Both cohorts had similar baseline demographics.

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Stroke Journal

DECEMBER 15, 2023

Stroke, Ahead of Print. Intracerebral hemorrhage is the most serious type of stroke, leading to high rates of severe disability and mortality. Hematoma expansion is an independent predictor of poor functional outcome and is a compelling target for intervention.

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Cardiometabolic Health Congress

NOVEMBER 22, 2024

Tirzepatide’s Dual Benefits in Obesity : Recent studies on tirzepatide , a GLP-1 receptor agonist, revealed significant weight loss and improved outcomes in sleep apnea patients. This program seeks to enhance patient outcomes by intensifying treatment based on CAD stages, including novel lipid-lowering therapies and antithrombotic strategies.

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CardiacWire

MARCH 20, 2024

The poor folks who ate all their meals within shorter time frames on the days before those two particular surveys had far worse outcomes over the 8-year median follow-up period. Participants with CVD who ate all their meals within an 8 to 10 hour window had a 66% higher risk of death from heart disease or stroke.

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DAIC

FEBRUARY 28, 2024

Untreated risk factors have a larger impact on risk for death following a serious heart event among survivors of childhood cancer relative to the general population, and therefore we shouldn’t just assume that because someone is young they don’t need risk factors like high blood pressure or high cholesterol treated.”

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DAIC

MAY 16, 2024

A new joint guideline from the American Heart Association (AHA), the American College of Cardiology (ACC) and nine other medical societies reports early diagnosis and treatment of peripheral artery disease is essential to improve outcomes and reduce amputation risk, heart attack, stroke and death for people with Peripheral Artery Disease (PAD).

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Open Heart

MAY 11, 2023

Objective There is a substantial incidence of stroke in patients with atrial fibrillation (AF) not receiving anticoagulation. The aim of our study was to investigate factors associated with patient refusal of anticoagulation and the clinical outcomes in these patients. to 1.76)) but lower all-cause mortality (aHR 0.59 (95% CI 0.43

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Journal of the American Heart Association

FEBRUARY 16, 2024

BackgroundPrior research suggests clinical effects of glucagon‐like peptide‐1 receptor agonists (GLP‐1RAs) and sodium‐glucose cotransporter‐2 inhibitors (SGLT2is) are mediated by changes in glycated hemoglobin, body weight, systolic blood pressure, hematocrit, and urine albumin‐creatinine ratio.

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