Journal of Clinical Investigation - Cardiology

DECEMBER 15, 2023

How these conditions are linked mechanistically remains unclear, especially two of these: obesity and elevated blood pressure. Pharmacological prevention of lipid droplet formation reverses the suppression of NO production in cell culture and in vivo and blunts blood pressure elevation in response to a high-fat diet.

Blood Pressure 105

Blood Pressure Obesity Pharmacology Diet 105

Heart BMJ

SEPTEMBER 16, 2024

Background Treating obesity may be a pathway to prevent and control hypertension. In the SURMOUNT-1 trial in people with obesity or overweight with weight-related complications, 72-week tirzepatide treatment led to clinically meaningful body weight and blood pressure reduction. mm Hg systolic and 4.2

Blood Pressure 52

Blood Pressure Obesity Hypertension 52

Science Daily - Heart Disease

FEBRUARY 5, 2024

Weight loss medication reduced both day and nighttime blood pressure levels, finds new study.

Blood Pressure 113

Blood Pressure Obesity 113

Medical Xpress - Cardiology

MARCH 31, 2024

Children and teenagers living with overweight or obesity are more likely to have high blood pressure as adults (aged 50–64 years), suggesting the processes behind the condition could begin as early as childhood, suggests new research being presented at this year's European Congress on Obesity (ECO) in Venice, Italy (12-15 May).

Blood Pressure 59

Blood Pressure Obesity Research 59

Frontiers in Cardiovascular Medicine

DECEMBER 20, 2023

The risk of hypertension increased with the presence of associated CV risk factors and comorbidities, particularly diabetes, obesity and the metabolic syndrome, and decreased with the intensity of physical activity. These patients were older (65.8 ± 10.9 vs. 51.6 ± 14.7 Regarding antihypertensive treatments, 6.1% two drugs, and 19.6%

Blood Pressure 134

Blood Pressure Hypertension Obesity Risk Factors 134

American Heart News - Heart News

NOVEMBER 11, 2024

Research Highlights: Heart disease, Type 2 diabetes, high blood pressure and obesity were more common and linked to reduced access to healthy food among people who lived in neighborhoods previously subjected to structural racism-based policies that.

Heart Disease 111

Heart Disease Blood Pressure Obesity Diabetes 111

Heart BMJ

SEPTEMBER 16, 2024

Obesity is a major global health issue and a leading cause of premature death. The prevalence of obesity has been rising faster than most other known modifiable risk factors. In a Global Burden of Disease analysis, the prevalence of obesity was found to have doubled in more than 70 countries from 1980 to 2013.

Obesity 52

Obesity Blood Pressure BMI Risk Factors 52

All About Cardiovascular System and Disorders

MAY 1, 2024

Guidelines on hypertension (high blood pressure) generally recommend measurement of blood pressure in both arms in the initial visit. They also suggest that the arm with higher blood pressure recording should be used to record blood pressure in subsequent visits.

Blood Pressure 40

Blood Pressure Risk Factors Chest Pain Heart attacks 40

Frontiers in Cardiovascular Medicine

APRIL 28, 2024

Following the Z-transformation of the independent variables, we evaluated the relationships between the four blood pressure indices and NAFLD through multivariable logistic regression models. This finding was confirmed in populations without exercise habits, under 60 years of age, with normal blood pressure, and in non-obese groups.

Blood Pressure 52

Blood Pressure Document Obesity Risk Factors 52

Circulation

NOVEMBER 11, 2024

Background:Impaired left atrial (LA) function is observed in obese patients, however, there is little information on when LA dysfunction begins to appear. To clarify this issue, we assessed LA volume and function in obese infants.Methods:Two-dimensional speckle-tracking echocardiography was performed in 96 infants aged 4 months.

Obesity 40

Obesity BMI Blood Pressure Circulation 40

Physiologically Speaking

APRIL 26, 2024

Prolonged sitting also leads to a bending of major arteries in our legs, leading to a blood flow pattern known as turbulent flow, blood pooling, impaired circulation, and endothelial dysfunction. They also had measures of body weight and circumferences and blood pressure assessed at these time points. kilograms (7.7

Blood Pressure 52

Blood Pressure Physiology Exercise Diet 52

CardiacWire

AUGUST 14, 2024

Rivus Pharmaceuticals’ HU6 is showing promise as a future obesity-related HFpEF treatment, after topline results from its Phase 2a HuMAIN trial revealed valuable weight, symptom, and cardiometabolic improvements – without the risk of muscle loss. blood pressure, pulse, glucose control, inflammation, lipid levels, and liver enzymes).

Obesity 52

Obesity Diet Quality of Life Blood Pressure 52

Cardiometabolic Health Congress

JANUARY 3, 2024

In today’s society, the prevalence of obesity has become a significant concern. have obesity, and this rate has increased by more than 10 percentage points in the past two decades. Understanding the prevalence of obesity is crucial in comprehending why events like Healthy Weight Week are essential. of adults in the U.S.

Obesity 97

Obesity Diabetes Blood Pressure BMI 97

American Heart News - Heart News

JUNE 4, 2024

ET Tuesday, June 4, 2024 DALLAS, June 4, 2024 — Driven by an older, more diverse population, along with a significant increase in risk factors including high blood pressure and obesity, total costs related to.

Risk Factors 143

Risk Factors Cardiovascular Disease Blood Pressure Obesity 143

Open Heart

OCTOBER 15, 2024

Patients with no history of atherosclerotic CVD started on blood pressure and/or lipid and/or glucose lowering treatments were identified retrospectively and interviewed at least 6 months after the initiation of medication. obese (body mass index≥30 kg/m 2 ) and 53.5% women; mean age 61.7±10.8 women; mean age 61.7±10.8

Blood Pressure 40

Blood Pressure Diabetes Risk Factors Obesity 40

DAIC

MAY 21, 2024

A new peer-reviewed study published in the Journal of the American Heart Association , JAHA, found that Hello Heart’s digital heart health program was associated with reductions in blood pressure (BP), total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), and weight.

Blood Pressure 52

Blood Pressure Cholesterol Risk Factors BMI 52

Hypertension Journal

DECEMBER 11, 2023

Background:Hypertensive disorders of pregnancy are associated with cardiovascular disease; however, patterns of blood pressure (BP) recovery are understudied. Hypertension, Ahead of Print. Pregnancy BPs were obtained during prenatal visits; postpartum BPs were prospectively obtained through home monitoring.

Blood Pressure 40

Blood Pressure Hypertension Obesity Cardiovascular Disease 40

Frontiers in Cardiovascular Medicine

DECEMBER 13, 2023

Background Worldwide obesity has a high prevalence, as well as carries a high risk of several chronic diseases, including hypertension. Studies of the association between obesity and ambulatory blood pressure (BP) are scarce and most use only body mass index (BMI) as indicator of adiposity.

Blood Pressure 64

Blood Pressure BMI Obesity Chronic Disease 64

Circulation

NOVEMBER 11, 2024

Background:Aldosterone regulates blood pressure and electrolyte balance. Insulin signaling was assessed 15 minutes after stimulation with 17 nM insulin.Results:Esaxerenone improved insulin sensitivity (P<0.05) without altering metabolic parameters in HFD-induced obese and db/db mice.

Obesity 40

Obesity Blood Pressure Diet Diabetes 40

DAIC

JUNE 18, 2024

A projected rise in heart disease and stroke – along with several key risk factors, including high blood pressure and obesity – is likely to triple related costs to $1.8 According to their projections, from 2020 to 2050, high blood pressure is expected to rise from 51.2% to 61% of the U.S. population. population.

Heart Disease 105

Heart Disease Blood Pressure Strokes Stroke 105

Hypertension Journal

OCTOBER 5, 2023

Inhibition of NOX2 with gp91ds-tat, both ex vivo and in vivo, mitigated the CINA-induced elevation in superoxide production and blood pressure response. Moreover, CINA increased vascular NOX2 expression and superoxide production exclusively in male offspring.

Blood Pressure 40

Blood Pressure Hypertension Obesity 40

Science Daily - Heart Disease

JUNE 4, 2024

Driven by an older, more diverse population, along with a significant increase in risk factors including high blood pressure and obesity, total costs related to cardiovascular disease (CVD) conditions are likely to triple by 2050, according to recent projections. At least 6 in 10 U.S.

Risk Factors 123

Risk Factors Cardiovascular Disease Blood Pressure Obesity 123

CardiacWire

FEBRUARY 11, 2024

The associations between obesity and hypertension are widely known, but a new JACC study reveals that weight-reducing gastric bypass surgery has a significant and lasting impact on patients’ need for antihypertensives. The GATEWAY trial assigned 100 participants (76% women, 43.8 of them achieved BPs below 130/80 mm Hg (vs.

Hypertension 111

Hypertension Blood Pressure Obesity BMI 111

CardiacWire

AUGUST 23, 2024

It looks like we might be able to add prediabetes and hypertension to the growing list of conditions that Eli Lilly’s “weight loss drug” tirzepatide is able to treat, after new analysis of the SURMOUNT-1 trial showed significant reductions in blood pressure and diabetes progression. mm Hg systolic and 4.2 of placebo-takers.

Hypertension 64

Hypertension Blood Pressure Diabetes Obesity 64

Journal of the American Heart Association

DECEMBER 29, 2023

BackgroundWe have previously reported that male mice exposed to maternal separation and early weaning (MSEW), a model of early life stress, show sympathetic activation and increased blood pressure in response to a chronic high‐fat diet. After chronic treatment with enalapril (2.5 mg/kg

Obesity 40

Obesity Blood Pressure Diet Circulation 40

Dr. Paddy Barrett

AUGUST 9, 2024

The 14 Factors Include: Hearing Loss High LDL cholesterol Less Education Traumatic Brain Injury Depression Social Isolation Hypertension Obesity Smoking Excess Alcohol Diabetes Physical Inactivity Air Pollution Visual Loss Dementia prevention, intervention, and care: 2024 report of the Lancet standing Commission When You Intervene Matters.

Dementia 103

Dementia Blood Pressure Obesity Cholesterol 103

Hypertension Journal

NOVEMBER 8, 2023

Alterations in microcirculation play a crucial role in the pathogenesis of cardiovascular and metabolic disorders such as obesity and hypertension. In obesity, PVAT becomes enlarged and inflamed, and the bioavailability of adiponectin is reduced. The inevitable consequence is a rise in peripheral resistance with higher blood pressure.

Obesity 40

Obesity Hypertension Blood Pressure Article 40

Circulation: Heart Failure

SEPTEMBER 12, 2023

Fasting blood samples collected at the time of the cardiopulmonary exercise test were used to assay obesity-related biomarkers. Our findings suggest that among the obesity-related biomarkers studied, higher levels of leptin and CRP are independently associated with increased odds of HFpEF, with odds ratios of 1.36 (95% CI, 1.09–1.70)

Biomarkers 40

Biomarkers Obesity Exercise Preserved Ejection Fraction 40

HCPLive

FEBRUARY 27, 2024

Results suggest a high prevalence of fatty liver in adults with chronic HCV, which was significantly associated with central obesity, elevated blood pressure, and metabolic syndrome.

Risk Factors 59

Risk Factors Blood Pressure Obesity 59

Cardiometabolic Health Congress

JULY 25, 2023

Can you please explain the concept of an obesity paradox? Salvatore Carbone, PhD: First, I’d like to point out that obesity is a major risk factor for cardiometabolic disease. 2, 3] This association is more pronounced for those with class I obesity, which is a body mass index (BMI) between 30-35 kg/m2.

Obesity 52

Obesity BMI Heart Failure Cardiovascular Disease 52

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

IntroductionClinical risk factors and co‐morbidities in obese male and female ischemic stroke patients with a history of smoking may contribute to differing stroke outcomes. Stroke: Vascular and Interventional Neurology, Volume 3, Issue S2 , November 1, 2023. Depression (OR = 0.432, 95% CI, 0.244–0.764, P<0.004), Previous TIA (OR = .319,

Obesity 40

Obesity Strokes Stroke Risk Factors 40

Dr. Paddy Barrett

NOVEMBER 15, 2024

Normal Blood Pressure. A study of almost 10,000 adults with obesity (BMI >30) who were evaluated for all LE8 factors and followed for over 7 years can give us some insight 1. Can we take the obesity risk off the table also? Not smoking. Adequate Sleep. Normal Cholesterol Levels. No Diabetes or Pre-Diabetes.

Heart Disease 83

Heart Disease Obesity Blood Pressure Cholesterol 83

Circulation

NOVEMBER 11, 2024

A physical examination was performed, heart rate was assessed, blood pressure was measured according to Korotkov method, body mass index (BMI) was calculated. The average level of blood pressure in the group with CHT amounted to systolic blood pressure (SBP) of 153.83±16.43 P < 0.05 in 1 group vs 3.2±1.6

Hypertension 40

Hypertension Blood Pressure Ultrasound Obesity 40

Journal of the American Heart Association

JANUARY 17, 2024

Cardiometabolic risk was assessed in young adulthood by carotid artery intima‐media thickness, systolic and diastolic blood pressure, obesity, percent body fat, android/gynoid ratio, and glycated hemoglobin. 0.22]), carotid artery intima‐media thickness (β=0.01 [95% CI, 0.0003–0.02]), systolic blood pressure (β=1.27 [95% CI, 0.09–2.45]),

Blood Pressure 78

Blood Pressure Obesity 78

Cardiometabolic Health Congress

NOVEMBER 14, 2024

42% of adults are considered obese , increasing their risk of diabetes, hypertension, and cardiovascular issues. Key Takeaways: Natriuretic Peptides : Useful for diagnosing and monitoring heart failure, particularly HFrEF, but challenging to interpret in patients with obesity due to peptide deficiency. In the U.S.,

CME 96

CME Obesity Heart Failure Biomarkers 96

Circulation

NOVEMBER 11, 2024

Empagliflozin (EMPA), the clinical benchmark, was used to confirm the relevance of the model.Methods:To induce obesity/metabolic syndrome, mild and HFpEF, C57BL6N mice were fed HFD (60% Kcal from fat) and water with L-NAME (0.5g/l) Consistent with elevated filling pressure, lung weight was increased in HFD/L-NAME mice (p<0.01

Preserved Ejection Fraction 40

Preserved Ejection Fraction Hypertension Blood Pressure Obesity 40

MIBHS

JULY 31, 2024

Here are some of the major ways in which chronic stress negatively impacts cardiovascular health: High Blood Pressure When you experience stress, your body releases hormones like cortisol and adrenaline, which cause your heart rate and blood pressure to spike.

Blood Pressure 52

Blood Pressure Heart attacks Heart Attack Heart Rhythm 52