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Blood pressure trial intervention shows mixed outcomes in chronic kidney disease patients

Medical Xpress - Cardiology

Stanford University School of Medicineled researchers have found that intensive blood pressure (BP) control produces cardiovascular benefits and increases the risk of adverse events in people with chronic kidney disease (CKD).

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2025 Heart Disease and Stroke Statistics: A Report of US and Global Data From the American Heart Association

Circulation

METHODS:The AHA, through its Epidemiology and Prevention Statistics Committee, continuously monitors and evaluates sources of data on heart disease and stroke in the United States and globally to provide the most current information available in the annual Statistical Update with review of published literature through the year before writing.

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Cost-Effectiveness of Intensive Blood Pressure Control in Youth With Chronic Kidney Disease

Hypertension Journal

BACKGROUND:Intensive blood pressure (BP) control in youth with chronic kidney disease (CKD) slows progression, delaying the need for kidney replacement therapy (KRT). Hypertension, Ahead of Print. We compared this intervention to usual care in a hypothetical population of youth with mild-to-moderate CKD.

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Mineralys Therapeutics Announces Phase 2 Clinical Trial of Lorundrostat

DAIC

a clinical-stage biopharmaceutical company focused on developing medicines to target hypertension, chronic kidney disease (CKD) and other diseases, hasannounced that the U.S. The primary outcome measure is absolute change in the frequency of apnea-hypopnea episodes. tim.hodson Wed, 01/08/2025 - 14:11 Jan.

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Hyperuricaemia elevates risk of short-term readmission and mortality in patients with heart failure

Open Heart

Results Baseline characteristics revealed significant differences between NUA and HUA groups, with the latter exhibiting a higher prevalence of males, chronic kidney disease (CKD) and elevated levels of various biomarkers. Our findings suggest that monitoring and managing SUA could be crucial in improving patient with HF outcomes.

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Adverse Effects of Aldosterone: Beyond Blood Pressure

Journal of the American Heart Association

Classically, activation of the MR in the renal tubular epithelium is responsible for sodium retention and volume expansion, raising systemic blood pressure.

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Efficacy and safety of angiotensin receptor–neprilysin inhibition in heart failure patients with end‐stage kidney disease on maintenance dialysis: A systematic review and meta‐analysis

European Journal of Heart Failure

Meta-analysis on the main outcomes of angiotensin receptorneprilysin inhibitor (ARNI) in heart failure (HF) patients with end-stage kidney disease (ESKD) on dialysis. However, the evidence on the benefits of ARNI in HF patients with end-stage kidney disease (ESKD) undergoing dialysis is limited.