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Targeted M‐Channel Activation in the Left Stellate Ganglion Protects Against Ischemia‐Induced Ventricular Arrhythmias in Canines

Journal of the American Heart Association

BackgroundAcute myocardial ischemia (AMI)triggered ventricular arrhythmias are closely linked to maladaptive sympathetic hyperactivity mediated via the left stellate ganglion (LSG). Retigabine pretreatment significantly suppressed ischemiainduced LSG hyperactivity and reduced sympathetic activation markers compared with controls.

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New Guidelines on Peripheral Artery Disease Issued by American Heart Association, American College of Cardiology and Leading Medical Societies

DAIC

Risk factors for PAD include smoking; having Type 1 or Type 2 diabetes, high blood pressure, high cholesterol, chronic kidney disease, atherosclerosis in other parts of the body (such as coronary artery disease); and being age 75 years or older. and Global Data From the American Heart Association.

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Diffuse Subendocardial Ischemia on the ECG. Left main? 3-vessel disease? No!

Dr. Smith's ECG Blog

The initial blood pressure was 80/palp with a heart rate of 104, respirations 20, oxygen saturations of 94% and a finger stick blood glucose of 268. In addition, the patient received 750 mL of fluid resuscitation with transient improvement of blood pressure.

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Does this T wave pattern mean anything?

Dr. Smith's ECG Blog

This may be in the strength of the pulse ( or the blood pressure recorded ) — or it may be in one or more waveforms in the ECG recording. Alternation in ST segment appearance ( or in the amount of ST elevation or depression ) — is often linked to ischemia.

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American College of Cardiology ACC.24 Late-breaking Science and Guidelines Session Summary

DAIC

24 will focus on the following three current guideline updates: American College of Cardiology (ACC)/American Heart Association (AHA) Guidelines 2023 Atrial Fibrillation Guideline - Pharmacology II: Strokes vs. Bleeds, What Do the Guidelines Tell Us About Practical Management in A-fib? The Guidelines Sessions at ACC.24

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Lowering Atherosclerotic Cardiovascular Disease Events by Treating Residual Inflammatory Risk

DAIC

1,12,13 While it is important to treat all known risk factors that contribute to ASCVD including high blood pressure, hyperlipidemia, diabetes, and obesity, physicians also need to recognize and treat systemic inflammation in CV disease. Therapeutic potential of colchicine in cardiovascular medicine: a pharmacological review.

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A woman in her 20s with syncope

Dr. Smith's ECG Blog

Pericardial tamponade is also associated with pulsus paradoxus which is an abnormally large drop in systolic blood pressure greater than 10 mmHg during inspiration. This may be in the strength of the pulse ( or the blood pressure recorded ) — or it may be in one or more waveforms in the ECG recording.