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9, 2025 Gender-based racism through microaggressions may be linked to higher bloodpressure postpartum and beyond, according to new research published in Hypertension , a peer-reviewed journal of the American Heart Association. Between these two groups, there was an average top number bloodpressure difference of 7.55
Welcome to the Physiology Friday newsletter. Physiologically Speaking is a reader-supported publication. When we don’t get enough sleep, our physiology suffers—insulin sensitivity tanks, cognitive function wanes, and physical performance is drastically impaired. I know I have (new dad here). and woke up at 7 a.m. (8
Welcome to the Physiology Friday newsletter. Physiologically Speaking is a reader-supported publication. When we are standing up or walking around (ambulating), our muscles contract to maintain posture and blood flow increases to meet the metabolic demands of the muscles.
Aerobic training is known to regulate bloodpressure more effectively when practiced in the evening than in the morning. The study is published in The Journal of Physiology.
a clinical-stage biopharmaceutical company focused on developing medicines to target hypertension, chronic kidney disease (CKD) and other diseases, hasannounced that the U.S. We believe suppression of aldosterone production by lorundrostat has the potential to reduce the nocturnal hypertension driving adverse cardiovascular outcomes.
Our body’s physiological processes oscillate on a 24-hour cycle known as the circadian rhythm. Circadian rhythms in bloodpressure and heart rate, among other functions, are crucial for cardiovascular health and preventing cardiovascular disease. In general, light exposure increases nighttime bloodpressure and heart rate.
Many times , an Innocuous question poses a real challenge, to our life time understanding of circulatory physiology. In patients with associated supine hypertension, the criteria for orthostatic hypotension allows for a drop of at least 30 mm Hg in SBP or 15 mm Hg in DBP. Can you discuss the answer to the question please ? Reference 1.Wahba
Hypertension, Ahead of Print. BACKGROUND:Circulating proteins in blood are involved in various physiological processes, but their contributions to bloodpressure regulation remain partially understood.
Exercise testing can serve as a powerful physiologic probe to unmask subclinical cardiovascular abnormalities well before disease onset. For example, bloodpressure changes during exercise (EBP) can reveal a latent tendency toward future development of hypertension.
Hypertension, Ahead of Print. Several microRNAs (miRNAs) strongly influence bloodpressure and the development of hypertension by modulating vascular, renal, and other physiological mechanisms. In addition, miRNAs may contribute to the genetic regulation of bloodpressure.
Hypertension, Ahead of Print. Race is a social construct, but self-identified Black people are known to have higher prevalence and worse outcomes of hypertension than White people.
As we age, we have lower levels of nitric oxide (NO), leading to endothelial dysfunction , arterial stiffening, and a rise in bloodpressure (hypertension) — three of the primary causes of cardiovascular disease. Some studies have shown the potential of NR in particular to reduce bloodpressure and arterial stiffness.
Hypertension, Ahead of Print. Previous basic and clinical investigations have identified various pathogenic factors and determinants of risk that contribute to hypertension. Nevertheless, the pathogenesis of hypertension has not been fully elucidated.
Hypertension, Ahead of Print. Essential hypertension, a multifaceted disorder, is a worldwide health problem. A complex network of genetic, epigenetic, physiological, and environmental components regulates bloodpressure (BP), and any dysregulation of this network may result in hypertension.
Hypertension, Ahead of Print. BACKGROUND:Potassium (K+)-deficient diets, typical of modern processed foods, increase bloodpressure (BP) and NaCl sensitivity.
Welcome to the Physiology Friday newsletter. Physiologically Speaking is a reader-supported publication. This newsletter is brought to you by Examine.com — the best place on the internet for health and nutrition information — and my new eBook, “VO2 Max Essentials.”
Welcome to the Physiology Friday newsletter. Physiologically Speaking is a reader-supported publication. This newsletter is brought to you by Examine.com — the best place on the internet for health and nutrition information — and my new eBook, “VO2 Max Essentials.”
Susceptibility MMD genes, including ring finger protein 213/mysterin andGUCY1A3, have also been linked to extracranial vascular disease and increased systolic bloodpressure. Bloodpressure measurements and antihypertensive agent use were recorded pre‐ and postoperatively. respectively. After a mean follow‐up of 34.3±18.1
Bakris , an internationally recognized and influential nephrologist and hypertension expert, who passed away on June 15, 2024, at the age of 72. Bakris’s distinguished career in medicine spanned over four decades, marked by significant contributions to the fields of diabetic kidney disease, hypertension, and nephropathy progression.
Hypertension, Ahead of Print. Excess dietary salt (NaCl) intake is strongly correlated with cardiovascular disease and is a major contributing factor to the pathogenesis of hypertension.
Hypertension, Ahead of Print. Salt (sodium chloride) is an essential nutrient required to maintain physiological functions. However, for most people, daily salt intake far exceeds their physiological need and is habitually greater than recommended upper thresholds.
Hypertension, Ahead of Print. BACKGROUND:Small arteries exhibit resting tone, a partially contracted state that maintains arterial bloodpressure. Perivascular adipose tissue (PVAT) has been shown to exert anticontractile effects on the blood vessels. This effect relaxes small arteries and regulates bloodpressure.
The Role of Wearable Technology in Heart Health Wearable tech is designed to monitor physiological data and provide actionable insights to users. For heart health, these devices use advanced sensors to track metrics like heart rate, blood oxygen levels, and even irregular heart rhythms.
However, prolonged exposure to stress can lead to persistently high levels of these hormones, contributing to increased heart rate, elevated bloodpressure, and inflammation, all of which raise the risk of heart disease. People with anxiety often experience elevated heart rates and increased bloodpressure.
Hypertension, Ahead of Print. Recently, some randomized trials, including the SPRINT (Systolic BloodPressure Intervention Trial), have suggested that improvements in cardiovascular risk factors may also slow cognitive decline and reduce the eventual development of dementia.
Hypertension, Ahead of Print. These data suggest that, during physiological stress, sympathetic reactivity is intact, but the peripheral pathway for sympathetic vasoconstriction may be impaired in HFpEF. BP, heart rate, and MSNA (microneurography) were measured during 6 to 10 minutes of supine rest and the 2-minute cold pressor test.
It was edited by Smith CASE : A 52-year-old male with a past medical history of hypertension and COPD summoned EMS with complaints of chest pain, weakness and nausea. The initial bloodpressure was 80/palp with a heart rate of 104, respirations 20, oxygen saturations of 94% and a finger stick blood glucose of 268.
Welcome to the Physiology Friday newsletter. Physiologically Speaking is a reader-supported publication. In a new study, evening exercise, but not morning exercise, reduced bloodpressure, lowered sympathetic activity, and improved baroreflex sensitivity in a group of adults with treated hypertension.
This includes, but is not limited to, PE, asthma/COPD exacerbation, hypoxic vasoconstriction from pneumonia, acute pulmonary hypertension exacerbation. Despite heparin and supportive care, the patients mental status and bloodpressure worsened. Troponin T returned elevated at 0.12 NT pro BP returned at 10,676 pg/mL.
Background Hypertension is a risk factor for bleeding events and is included in the HAS-BLED (Hypertension, Abnormal renal/liver function, Stroke, Bleeding history or predisposition, Labile INR, Elderly, Drugs/Alcohol concomitantly) score.
Introduction:Blood pressure is a simple physiologic parameter that is always measured, can be modulated, and may affect the outcome. This data will be beneficial in educating medical staff and making sure to optimize bloodpressure especially during transfer to a certified stroke center.
High bloodpressure disrupts natural day-and-night bloodpressure dipping patterns in males and females, according to a new study from Tulane University School of Medicine. The findings are published in the American Journal of Physiology-Heart and Circulatory Physiology.
Background:Common genetic variation explains up to 40% of bloodpressure variation. Despite this compelling physiological impact, the role of common genetic variation in bloodpressure treatment and their sequelae remains understudied. 1.18) and 30% (OR 1.30, 95%CI 1.24-1.36) for both analyses).Conclusions:Among
6 [link] Insufficient sleep has been linked to a greater risk for several health conditions including obesity, diabetes, hypertension, and cognitive decline. The amount of calcium in the blood vessels (known as arterial calcification), a marker of subclinical atherosclerosis, is higher in people with a short sleep duration.
For this reason, the guidelines place much emphasis on risk factor management throughout the disease continuum, offering recommendations such as obesity management, weight loss, physical activity, smoking cessation, alcohol moderation, hypertension, as well as other comorbidities.
These indirect and direct factors can lead to obesity, hypertension, hyperlipidemia, diabetes, ischemia with no obstructive coronary artery disease (INOCA), CAD, myocardial infarction (MI), and stroke via the hypothalamic-pituitary-adrenal axis, sympathetic-adrenal-medullary system, sympathetic nervous system, and hypoestrogenemia.
While CAC is typically associated with traditional risk factors such as age, hypertension, and smoking, paradoxically elevated CAC scores have been observed in male endurance athletes despite their otherwise healthy profiles. Physiologically Speaking is a reader-supported publication.
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