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(MedPage Today) -- A computerized clinical decision support (CDS) tool for primary care helped lower bloodpressure (BP) in patients with chronic kidneydisease (CKD) and uncontrolled hypertension, a cluster-randomized trial found. When primary.
Hypertension is a leading cause of morbidity and mortality worldwide and poses a major risk factor for cardiovascular diseases and chronic kidneydisease.
Akshay Desai, MD “Compared to placebo, a single injection of zilebesiran resulted in clinically meaningful reductions in bloodpressure at three months when added to commonly used antihypertensive treatments,” said Akshay Desai, MD, MPH , a cardiologist at Brigham and Women’s Hospital in Boston and a study coauthor. “In
High bloodpressure, also known as hypertension, is a common condition that affects millions of people worldwide. Often referred to as the silent killer, hypertension can quietly damage your heart and other vital organs over time. What Is High BloodPressure?
The BACKBEAT pivotal study will evaluate the efficacy and safety of atrioventricular interval modulation (“AVIM”) therapy (also known as BackBeat CNT), for the treatment of pacemaker-indicated patients with uncontrolled hypertension despite the use of antihypertensive medications. Orchestra BioMed and Medtronic, Inc. Kowal, M.D.,
Mineralocorticoid excess commonly leads to hypertension (HTN) and kidneydisease. However, finerenone was particularly effective in reducing albuminuria and improving gene expression changes in podocytes and proximal tubule cells, even with an equivalent reduction in bloodpressure.
Hypertension, Ahead of Print. BACKGROUND:Intensive bloodpressure (BP) control in youth with chronic kidneydisease (CKD) slows progression, delaying the need for kidney replacement therapy (KRT). We compared this intervention to usual care in a hypothetical population of youth with mild-to-moderate CKD.
Does a computerized clinical decision support (CDS) system based on behavioral economic principles and human-centered design lead to a decrease in systolic bloodpressure (SBP) in patients with chronic kidneydisease (CKD) and uncontrolled hypertension?
milla1cf Fri, 06/28/2024 - 19:07 June 28, 2024 — AstraZeneca has set out a new ambition for Healthy Heart Africa , its flagship health equity initiative, to target a broader range of non-communicable diseases (NCDs), including chronic kidneydisease (CKD) as well as hypertension and cardiovascular disease.
BackgroundBoth nighttime systolic bloodpressure and pulse rate are associated with adverse outcomes in patients with chronic kidneydisease (CKD). However, nighttime double product (DP), which is the product of nighttime systolic bloodpressure and pulse rate, has not yet been investigated in this context.
Panelists discuss how chronic kidneydisease (CKD) and uncontrolled hypertension create a damaging cycle, in which hypertension accelerates kidney damage while declining kidney function makes bloodpressure harder to control.
Hypertension, Volume 80, Issue 12 , Page 2533-2543, December 1, 2023. BACKGROUND:Hypertension frequently accompanies chronic kidneydisease (CKD) as etiology and sequela. We defined CKD as a sustained estimated glomerular filtration rate value <60 mL/min per 1.73 m2or a urine albumin-to-creatinine ratio ≥30 mg/g.
Panelists discuss how poor medication adherence and comorbidities such as chronic kidneydisease (CKD) contribute to uncontrolled hypertension despite the availability of numerous treatment options, highlighting key challenges in achieving effective bloodpressure management.
Background:Dietary magnesium (Mg+2) deficiency has been linked to hypertension, chronic kidneydisease, and cardiovascular disease. High sodium intake and reduced dietary Mg+2consumption are associated with elevated bloodpressure.
Background Hypertension is a silent killer that causes serious health issues in all parts of the world. It is risk factor for cardiovascular disease, stroke and kidneydisease. Self-monitoring practice has been identified as an important component of hypertension management. and then exported to SPSS V.25
Hypertension, Ahead of Print. Hypertension is one of the most commonly treated conditions in modern medical practice, but despite its long history, it was largely ignored until the midpoint of the 20th century. Early treatments included acupuncture, venesection, and bleeding by leeches.
Background Preeclampsia (PE) is associated with subsequent higher risk of cardiovascular and kidneydisease. Serum copeptin, as a proxy for vasopressin, and urinary uromodulin, were associated with PE physiopathology and kidney functional mass respectively.
Bakris , an internationally recognized and influential nephrologist and hypertension expert, who passed away on June 15, 2024, at the age of 72. Bakris’s distinguished career in medicine spanned over four decades, marked by significant contributions to the fields of diabetic kidneydisease, hypertension, and nephropathy progression.
Susceptibility MMD genes, including ring finger protein 213/mysterin andGUCY1A3, have also been linked to extracranial vascular disease and increased systolic bloodpressure. Bloodpressure measurements and antihypertensive agent use were recorded pre‐ and postoperatively. respectively. months in adults (33.8±14.9
Key findings presented at the conference included disparities in access to kidney transplantation and waitlisting based on race and neighborhood characteristics, racial and ethnic differences in incident chronic kidneydisease (CKD), and the use of motivational strategies to improve dialysis nonadherence among African American patients.
Introduction:High levels of bloodpressure (BP) are responsible for 7.6 The diagnosis of hypertension is associated with a significant increase in the risk of kidney or cardiovascular events, with no prior history of these events. The AAMR for hypertensive heart and renal disease with heart failure was 0.1
Here, for example, plucked at random, is a reference to the latest NICE guidelines on the management of hypertension (high bloodpressure) in adults. But this, the primary guideline on hypertension for adults, is but one of many. There are associated guidelines on hypertension in pregnancy. Has anyone.
Introduction:Blood pressure targets for the elderly are still controversial, there is a lack of certainty about the benefit and safety of targeting ≤ 130mmHg systolic bloodpressure. of patients had cardiovascular disease, 10.9% chronic kidneydisease. diabetes, and 15.5%
Hypertension, Ahead of Print. BACKGROUND:Polycystic kidneydisease is the most common hereditary kidney disorder with early and frequent hypertension symptoms.
a clinical-stage biopharmaceutical company focused on developing medicines to target hypertension, chronic kidneydisease (CKD) and other diseases, hasannounced that the U.S. tim.hodson Wed, 01/08/2025 - 14:11 Jan. 8, 2025 Mineralys Therapeutics, Inc.,
Hypertension, Ahead of Print. Excess dietary sodium intake and insufficient dietary potassium intake are both well-established risk factors for hypertension. Despite some successful initiatives, efforts to control hypertension by improving dietary intake have largely failed because the changes required are mostly too hard to implement.
Aprocitentan (Tryvio) Approved: March 20, 2024 Indication: Hypertension in adults Administration: Oral Mechanism: Endothelin A and B receptor antagonist Developer: Idorsia Pharmaceuticals Significance: First and only FDA-approved endothelin receptor antagonist for high bloodpressure that remains uncontrolled with existing treatments.
The developed model was validated internally and externally using an independent external cohort (n=138). Among 322 patients, 138 (42.9%) survived postdischarge.
Hypertension, diabetes, hyperlipidemia, and chronic kidneydisease are well-known cardiovascular risk factors for ICH. Stroke, Volume 56, Issue Suppl_1 , Page A49-A49, February 1, 2025. Introduction:Intracranial hemorrhage (ICH) is the most severe adverse effect of anticoagulation in atrial fibrillation (AF) patients.
Effects of resistance training on traditional CVD risk factors Bloodpressure Resistance exercise training has been shown to improve resting bloodpressure in cohorts of healthy adults and adults with varying levels of high bloodpressure.
Effects of resistance training on traditional CVD risk factors Bloodpressure Resistance exercise training has been shown to improve resting bloodpressure in cohorts of healthy adults and adults with varying levels of high bloodpressure.
There are significant data that show that if you have obesity, you have a high risk of developing coronary heart disease, heart failure, type 2 diabetes (T2D) or risk factors such as hypertension and dyslipidemia. [1] So, if a patient is concerned about their weight or bloodpressure, treatment needs to be individualized accordingly.
Background Hypertension is a risk factor for bleeding events and is included in the HAS-BLED (Hypertension, Abnormal renal/liver function, Stroke, Bleeding history or predisposition, Labile INR, Elderly, Drugs/Alcohol concomitantly) score.
AF is associated with an increased risk of death as well as multiple adverse outcomes, including stroke, cognitive impairment or dementia, myocardial infarction, sudden cardiac death, heart failure (HF), chronic kidneydisease (CKD), and peripheral artery disease (PAD).
ObjectiveTo investigate the sex differences in the efficacy of renal denervation (RDN) in patients with resistant hypertension (RHT) concerning the size of abdominal fat depots, changes in biomarkers of sympathetic activity, and renal function.Materials and methods24 men (56.57.8 years) and 33 women (59.58.4 In men, the eGFR did not change.
Background and Purpose:Chronic kidneydisease (CKD) is associated with an increased risk of stroke and worse outcomes, yet it is often asymptomatic, with an estimated 90% of individuals unaware they have CKD until its later stages. Stroke, Volume 56, Issue Suppl_1 , Page A102-A102, February 1, 2025. female, 22.1%
Cardiovascular disease remains the leading cause of death worldwide , claiming 18 million lives annually. 42% of adults are considered obese , increasing their risk of diabetes, hypertension, and cardiovascular issues. In the U.S., SELECT Trial Results : Semaglutide 2.4
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