Endothelial lipid droplets suppress eNOS to link high fat consumption to blood pressure elevation
Journal of Clinical Investigation - Cardiology
DECEMBER 15, 2023
How these conditions are linked mechanistically remains unclear, especially two of these: obesity and elevated blood pressure. Pharmacological prevention of lipid droplet formation reverses the suppression of NO production in cell culture and in vivo and blunts blood pressure elevation in response to a high-fat diet.
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