Physiologically Speaking

AUGUST 9, 2024

The debate over whether carbohydrates or sugar are the true culprits behind modern health issues has long stirred controversy among nutrition experts, diet enthusiasts, and the general public alike. This has led to widespread recommendations to drastically reduce "free sugars" in the diet.

Physiology 69

Physiology Diet Cholesterol Biomarkers 69

GEMMS

NOVEMBER 22, 2023

Regular exercise, a balanced diet, and lifestyle choices such as not smoking and managing stress are all crucial for achieving and maintaining optimal cardiovascular health. Maintaining cardiovascular health reduces the risk of developing various heart diseases, including heart attack, stroke, and high blood pressure.

Blood Pressure 52

Blood Pressure Cholesterol Diet Exercise 52

Dr. Paddy Barrett

JANUARY 24, 2025

I am a fan of using low-carb diets for both weight loss and improving metabolic health. Low-carb diets have consistently shown benefits in improving these parameters 1. In the early 1970’s a group of 106 severely obese patients were put on a diet that resulted in an average weight loss of 63 Kg (139 lbs) over about one year 2.

Diet 52

Diet Obesity Diabetes Cholesterol 52

Journal of the American Heart Association

FEBRUARY 19, 2025

The aim of this study was to examine the effect of daily avocado intake for 26 weeks on LE8 in adults with abdominal obesity.Methods and ResultsAn ancillary analysis including participants (n=969; aged 5114 years) from the HAT (Habitual Diet and Avocado Trial), a randomized controlled trial, was conducted. points [95% CI, 0.41

Diet 40

Diet Blood Pressure Obesity 40

Circulation: Cardiovascular Quality & Outcomes

APRIL 14, 2025

Poor sleep health is associated with cardiometabolic disease and related risk factors, including heart disease, stroke, elevated blood pressure and lipid levels, inflammation, glucose intolerance, obesity, physical inactivity, poor diet, unhealthy substance use, poor mental health, and increased all-cause and cardiovascular mortality, and is associated (..)

Health Disparities 40

Health Disparities Blood Pressure Diet Obesity 40

Dr. Paddy Barrett

AUGUST 16, 2024

Overweight/Obesity. Falling into the class of obesity with a BMI of greater than 30 makes this more likely, but so also does having excess visceral fat deposition with significant metabolic consequences at a BMI less than 30. They are not crash diets to fit into your swimwear. All diets work. For a while.

Obesity 52

Obesity Blood Pressure Diet Exercise 52

Circulation

NOVEMBER 11, 2024

Empagliflozin (EMPA), the clinical benchmark, was used to confirm the relevance of the model.Methods:To induce obesity/metabolic syndrome, mild and HFpEF, C57BL6N mice were fed HFD (60% Kcal from fat) and water with L-NAME (0.5g/l) Mean blood pressure was consistently increased in HFD/L-NAME mice (p<0.05 l) for 8 weeks.

Preserved Ejection Fraction 40

Preserved Ejection Fraction Hypertension Blood Pressure Obesity 40

AMS Cardiology

AUGUST 15, 2023

High blood pressure – Hypertension is a significant risk factor for heart disease. Routine blood pressure checks are essential to maintaining a healthy heart as high blood pressure often has no symptoms. It damages blood vessels, decreases oxygen to the heart and raises the risk of heart disease.

Heart Disease 52

Heart Disease Blood Pressure Risk Factors Cholesterol 52

Wellnest

FEBRUARY 28, 2023

There is growing awareness of the risks of inadequate sleep for heart health, even though it is already well established that variables, including a poor diet, little exercise, and smoking, can affect the heart. High blood pressure and heart disease are related to insomnia. How does sleep impact heart health?

Blood Pressure 52

Blood Pressure Heart Failure Heart attacks Heart Attack 52

Frontiers in Cardiovascular Medicine

JANUARY 4, 2024

p  = 0.009, T3), diastolic blood pressure [OR = 0.41, p  = 0.024 (T2), and OR = 0.47, p  = 0.049 (T3)], and creatinine kinase (OR = 0.27, p  = 0.014, T3) compared to T1. A higher Zn/Cu ratio may protect against CVD, while elevated Cu levels are linked to obesity, fibrinogen levels, and HbA1C.

Cardiovascular Disease 59

Cardiovascular Disease Blood Pressure Diet Obesity 59

MIBHS

NOVEMBER 30, 2023

However, prolonged exposure to stress can lead to persistently high levels of these hormones, contributing to increased heart rate, elevated blood pressure, and inflammation, all of which raise the risk of heart disease. People with anxiety often experience elevated heart rates and increased blood pressure.

Blood Pressure 52

Blood Pressure Heart Disease Blood Clot Physiology 52

Physiologically Speaking

DECEMBER 22, 2023

Clinically, about 1/3 of adults have metabolic syndrome — a cluster of conditions including abdominal obesity, high blood pressure, high blood glucose, high triglycerides, and low HDL cholesterol. link] Of course, diet is an important component of metabolic health, but exercise also plays an indispensable role.

Exercise 52

Exercise Physiology Blood Pressure Cholesterol 52

Physiologically Speaking

DECEMBER 22, 2023

Clinically, about 1/3 of adults have metabolic syndrome — a cluster of conditions including abdominal obesity, high blood pressure, high blood glucose, high triglycerides, and low HDL cholesterol. link] Of course, diet is an important component of metabolic health, but exercise also plays an indispensable role.

Exercise 52

Exercise Physiology Blood Pressure Cholesterol 52

MIBHS

FEBRUARY 28, 2025

While much attention is given to modifiable risk factors such as diet, exercise, and smoking, the role of genetics in heart disease is equally critical yet less understood by the general public. Diet: Follow a heart-healthy diet rich in fruits, vegetables, whole grains, lean proteins, and healthy fats.

Genetic predisposition 52

Genetic predisposition Heart Disease Cholesterol Blood Pressure 52

MIBHS

MARCH 15, 2025

Understanding the effects of alcohol on heart disease, blood pressure, and heart muscle function is essential for making informed decisions about alcohol intake. How Alcohol Affects Heart Function Blood Pressure and Heart Disease Risk One of the most significant concerns related to alcohol consumption is its effect on blood pressure.

Blood Pressure 52

Blood Pressure Heart Rhythm Blood Clot Heart Disease 52

Dr. Paddy Barrett

NOVEMBER 15, 2024

Normal Blood Pressure. A study of almost 10,000 adults with obesity (BMI >30) who were evaluated for all LE8 factors and followed for over 7 years can give us some insight 1. Can we take the obesity risk off the table also? Not smoking. Adequate Sleep. Normal Cholesterol Levels. No Diabetes or Pre-Diabetes.

Heart Disease 98

Heart Disease Obesity Blood Pressure Cholesterol 98

Dr. Paddy Barrett

DECEMBER 12, 2023

That’s what the field of obesity therapeutics feels like right now. Share In addition to reductions in weight, multiple risk parameters, including blood pressure, waist circumference and lipids, also improve. What seems clear, however, is that a higher protein diet minimises the degree of lean mass loss 8.

Obesity 106

Obesity Heart attacks Heart Attack Diet 106

AMS Cardiology

NOVEMBER 21, 2024

This is because stress causes an increase in cortisol – the primary stress hormone – leading to increases in blood pressure , cholesterol, blood sugar and heart rate. But, sometimes, prolonged stress or sudden, drastic spikes in stress can cause palpitations, trigger heart attacks or increase your risk for heart disease.

Heart attacks 52

Heart attacks Heart Attack Heart Failure Blood Pressure 52

Cardiometabolic Health Congress

JULY 25, 2023

Can you please explain the concept of an obesity paradox? Salvatore Carbone, PhD: First, I’d like to point out that obesity is a major risk factor for cardiometabolic disease. 2, 3] This association is more pronounced for those with class I obesity, which is a body mass index (BMI) between 30-35 kg/m2.

Obesity 52

Obesity BMI Heart Failure Cardiovascular Disease 52

Dr. Paddy Barrett

JANUARY 23, 2024

Subscribe now Blood Pressure Approximately 50% of all Western adults have high blood pressure 7. The majority of this high blood pressure is undiagnosed and, therefore, untreated. As a consequence, high blood pressure is the single most important risk factor for early death worldwide 8.

Heart Disease 106

Heart Disease Blood Pressure Dementia Atherosclerosis 106

Physiologically Speaking

SEPTEMBER 20, 2024

In my opinion, it’s even more important than diet and sleep, to an extent. Let’s admit that we face an energy abundance today — in most industrial societies, the problem is caloric surplus and overweight/obesity rather than malnutrition or food scarcity.

Exercise 114

Exercise Physiology Blood Pressure Obesity 114

Dr. Paddy Barrett

MAY 24, 2024

As the line goes: “You can’t outrun a bad diet, and you can’t out diet not exercising.” The DiRECT Trial used a calorie-restricted diet over 3-5 months and also withdrew diabetic and blood pressure control medications. But What Diet Should I Use To Lose The Weight? ” Diabetes.

Diabetes 110

Diabetes Diet BMI Exercise 110

CardiacWire

AUGUST 14, 2024

Rivus Pharmaceuticals’ HU6 is showing promise as a future obesity-related HFpEF treatment, after topline results from its Phase 2a HuMAIN trial revealed valuable weight, symptom, and cardiometabolic improvements – without the risk of muscle loss. blood pressure, pulse, glucose control, inflammation, lipid levels, and liver enzymes).

Obesity 52

Obesity Diet Quality of Life Blood Pressure 52

MIBHS

OCTOBER 31, 2023

Eat a Balanced Diet A heart healthy diet is the foundation of cardiovascular health. Additionally, watch your sodium intake to keep your blood pressure in check. Poor sleep can lead to weight gain, high blood pressure, and an increased risk of heart disease. tips to keep your heart in optimal condition.

Blood Pressure 52

Blood Pressure Heart Disease Diet Risk Factors 52

AMS Cardiology

SEPTEMBER 30, 2024

Regular heart check-ups offer several benefits including: Early detection of heart disease : Many heart conditions such as high blood pressure, high cholesterol and coronary artery disease can be detected early through regular screenings. Early detection allows for timely treatment and can help prevent serious complications.

Heart Disease 52

Heart Disease Blood Pressure Cholesterol Exercise 52

MIBHS

NOVEMBER 15, 2023

Hypertension Hypertension, or high blood pressure , is often referred to as the “silent killer” because it typically shows no symptoms until it leads to more severe health issues. Regular blood pressure checks and lifestyle modifications, such as a heart-healthy diet and exercise, are essential for managing this risk.

Blood Pressure 52

Blood Pressure Cholesterol Heart Disease Risk Factors 52

Wellnest

AUGUST 24, 2023

Unhealthy lifestyle habits, genetics, obesity, and other risk factors can contribute to cardiac disease at any stage of life. A number of lifestyle factors, including a poor diet, inactivity, smoking, high blood pressure, diabetes, obesity, and stress, have an impact on cardiac health.

Heart Disease 52

Heart Disease Blood Pressure Cholesterol Genetic predisposition 52

Physiologically Speaking

DECEMBER 15, 2023

Effects of resistance training on traditional CVD risk factors Blood pressure Resistance exercise training has been shown to improve resting blood pressure in cohorts of healthy adults and adults with varying levels of high blood pressure.

Physiology 52

Physiology Exercise Blood Pressure Risk Factors 52

Physiologically Speaking

DECEMBER 15, 2023

Effects of resistance training on traditional CVD risk factors Blood pressure Resistance exercise training has been shown to improve resting blood pressure in cohorts of healthy adults and adults with varying levels of high blood pressure.

Physiology 52

Physiology Exercise Blood Pressure Risk Factors 52

Dr. Paddy Barrett

SEPTEMBER 26, 2023

Share For people with OSA during sleep, there are recurrent episodes where the airway collapses and obstructs the passage of air to the lungs, resulting in: Lack of oxygen Significant variations in blood pressure, heart rate and other physiological metrics. Now imagine someone doing that to you every night.

Blood Pressure 52

Blood Pressure Cardiovascular Disease Atrial Fibrillation Coronary Artery Disease 52

Cardiometabolic Health Congress

FEBRUARY 1, 2024

Depression can lead to unhealthy behaviors such as poor diet, sedentary lifestyle, smoking, and non-adherence to medication, which are risk factors for CVD.

Cardiovascular Disease 105

Cardiovascular Disease Coronary Artery Bypass Graft Heart Disease Risk Factors 105

Cardiometabolic Health Congress

MAY 10, 2024

These indirect and direct factors can lead to obesity, hypertension, hyperlipidemia, diabetes, ischemia with no obstructive coronary artery disease (INOCA), CAD, myocardial infarction (MI), and stroke via the hypothalamic-pituitary-adrenal axis, sympathetic-adrenal-medullary system, sympathetic nervous system, and hypoestrogenemia.

Coronary Artery Disease 59

Coronary Artery Disease Obesity Chest Pain Ischemia 59

MIBHS

DECEMBER 13, 2024

Lifestyle Habits: Obesity, smoking, excessive alcohol consumption, and lack of exercise can all negatively impact sexual function. Factors such as age, severity of heart disease, risk factors, and lifestyle choices (such as smoking and diet) can all influence the outcome. Patients may experience temporary ED while their body heals.

Coronary Artery Bypass Graft 52

Coronary Artery Bypass Graft Diet Heart Disease Risk Factors 52

Physiologically Speaking

DECEMBER 13, 2024

Post-acclimation, the participants experienced an average drop of 10 mmHg in systolic blood pressure and 7 mmHg in diastolic pressure. ” An alternative approach for the extremely exercise- or diet-resistant? Cold acclimation with shivering improves metabolic health in adults with overweight or obesity.

Physiology 59

Physiology Obesity Exercise Research 59

DAIC

MARCH 8, 2024

Food and Drug Administration ( FDA ) has approved an additional indication for Wegovy ( semaglutide ) to reduce the risk of major cardiovascular events such as death, heart attack, or stroke in adults with known heart disease and with either obesity or overweight along with a reduced calorie diet and increased physical activity.

Obesity 111

Obesity Heart Disease Heart attacks Heart Attack 111

Wellnest

JULY 19, 2023

However, recent studies have observed that people below 40 are also experiencing heart attacks due to high blood pressure, cholesterol, diabetes, smoking, obesity, a sedentary lifestyle, and social and mental stress. Keep an eye on blood pressure. Obesity or being overweight can increase the risk of heart disease.

Heart attacks 52

Heart attacks Heart Attack Blood Pressure Myocardial Infarction 52

Physiologically Speaking

MAY 3, 2024

ICYMI On Wednesday, I published a post discussing the different metabolic effects of the ketogenic diet and exogenous ketones during exercise. KNG1 and 2 are speculated to play a role in exercise’s effect on improving blood pressure and insulin sensitivity. Welcome to the Physiology Friday newsletter.

Exercise 95

Exercise Physiology Research Kidney Disease 95