Dr. Paddy Barrett

FEBRUARY 7, 2025

By the time you get to age 80, you will almost certainly have evidence of plaque in your coronary arteries - you will have heart disease. Normal Cholesterol Levels. Normal Blood Pressure. But first, let’s get some facts straight. Over a long enough time frame, pretty much everyone will get heart disease.

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MIBHS

OCTOBER 31, 2024

High Blood Pressure (Hypertension) Persistent high blood pressure forces the heart to work harder to pump blood. Coronary Artery Disease (CAD) CAD, which involves the narrowing or blockage of coronary arteries due to plaque buildup, can reduce blood flow to the heart.

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Dr. Paddy Barrett

SEPTEMBER 20, 2024

When we say heart disease, what we really mean is plaque in the artery wall. The fundamental cause of atherosclerosis is when a cholesterol particle crosses into the artery wall from the bloodstream, gets stuck, and sets off an inflammatory process 1. Every cholesterol particle has a protein marker called ApoB on its outside.

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Dr. Paddy Barrett

JANUARY 23, 2024

However, most adults will start to develop advanced plaque in their coronary arteries early in life. By age 66, more than half of all females will have evidence of advanced plaque in their coronary arteries, as seen on a CT calcium score. Coronary atherosclerosis, as evidenced by an abnormal CAC score, is a measure of advanced plaque.

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Medical Xpress - Cardiology

JULY 2, 2024

Vascular plaque. Perhaps your blood pressure has been a little too high for a little too long, putting strain on your blood vessels. It starts with inflammation.

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Frontiers in Cardiovascular Medicine

MARCH 4, 2024

The complex development of atherosclerosis manifests as intimal plaque which occurs in the presence or absence of traditional risk factors. For cardiovascular disease, only low-density lipoprotein cholesterol and blood pressure are approved as surrogates for cardiovascular disease.

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Dr. Paddy Barrett

DECEMBER 19, 2023

You cannot eliminate the plaque entirely, but multiple clinical trials have shown plaque regression using high-intensity cholesterol-lowering treatments, which I have discussed previously. All of these parameters are important and need to be considered when evaluating plaque regression. REVERSAL Investigators.

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Dr. Paddy Barrett

JUNE 21, 2024

Therefore, if someone presents with an event earlier than this age, they likely have been building up plaque for a considerable period prior to this. He had high blood pressure and high cholesterol most of his life, and he wasn’t great at taking his tablets.” “Dad had a heart attack at 78.

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All About Cardiovascular System and Disorders

APRIL 30, 2024

Plaque regression can be demonstrated by ultrasound evaluation of the carotids which are easily accessible. Regular exercise can bring down the blood pressure in the long run. Though blood pressure rises progressively with increasing exercise, it reduces the resting blood pressure in the long run.

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AMS Cardiology

JANUARY 21, 2023

We all want to be heart-healthy and ensuring our cholesterol levels are in the normal range is one of the most critical steps. High cholesterol can increase your risk of severe conditions like heart disease and heart attacks. Continue reading to learn four heart-healthy habits that can improve your cholesterol.

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GEMMS

NOVEMBER 22, 2023

Maintaining cardiovascular health reduces the risk of developing various heart diseases, including heart attack, stroke, and high blood pressure. Factors such as smoking, high blood pressure, high cholesterol levels, obesity, and a sedentary lifestyle significantly increase the risk of developing cardiovascular disease.

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AMS Cardiology

NOVEMBER 4, 2023

Understanding Peripheral Artery Disease Peripheral artery disease or PAD is a condition in which plaque builds up in the arteries that lead to the legs and feet. A diet rich in fruits, vegetables, whole grains and lean proteins can help control blood pressure, cholesterol levels and weight.

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AMS Cardiology

AUGUST 15, 2023

High blood pressure – Hypertension is a significant risk factor for heart disease. Routine blood pressure checks are essential to maintaining a healthy heart as high blood pressure often has no symptoms. Family history – If a close family member has had heart disease, it can raise your risk.

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DAIC

MAY 16, 2024

PAD is a serious, progressive cardiovascular disease primarily caused by a buildup of fatty plaque in the blood vessels, or atherosclerosis. This plaque narrows the blood vessels and reduces blood flow to the legs and feet, which may significantly impair physical function, walking performance and quality of life.

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MIBHS

OCTOBER 31, 2023

Limit your intake of saturated and trans fats, as they can raise cholesterol levels and increase the risk of heart disease. Additionally, watch your sodium intake to keep your blood pressure in check. Poor sleep can lead to weight gain, high blood pressure, and an increased risk of heart disease.

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All About Cardiovascular System and Disorders

APRIL 22, 2024

If these clots migrate to the blood vessels of the brain, a stroke may result. Cholesterol levels go up when thyroid function comes down. This in turn can enhance the chance of plaque build-up in the blood vessels of the heart (coronary arteries).

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Dr. Paddy Barrett

AUGUST 1, 2023

A CTCA provides much more anatomical detail and can identify advanced plaque often missed by CT Coronary Artery Calcium Score scans alone. There are 3 types of coronary atherosclerosis visible on CTCA: Calcified Plaque - Easily Identified on both CT CAC & CTCA scans. Subscribe now How Often Does A CT CAC Scan Miss Plaque?

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DAIC

JANUARY 23, 2024

Atherosclerotic cardiovascular disease (ASCVD), caused by plaque buildup in arterial walls, is one of the leading causes of disability and death worldwide.1,2 7 Research has shown inflammation plays a significant role in the development of atherosclerosis and ASCVD,8-10 and even the formation of plaque.11 4 In the U.S.

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Dr. Sanjay Gupta

DECEMBER 19, 2022

Infections and inflammation of the heart eg myocarditis will cause acute inflammation of the heart and therefore may compromise the pumping ability of the heart Conditions such as high blood pressure will make the heart work harder and as it does so it will become more muscular. The plaques can damage us in 2 ways.

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Dr. Paddy Barrett

JULY 12, 2024

If you have high LDL cholesterol and are unsure what that means for your risk of heart disease, this article is for you. Over the course of your lifetime, your LDL cholesterol will slowly increase. By midlife, the average male and female will see a significant rise in their LDL cholesterol. to 4 mmol (135 to 155 mg/dl).

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Dr. Paddy Barrett

MAY 31, 2024

Heart disease, the build-up of plaque in the coronary arteries, typically starts years, if not decades, prior to an event. These noninvasive scans look directly at the coronary arteries rather than assessing for the risk factors for coronary artery disease eg LDL cholesterol, high blood pressure etc. Here’s why.

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DAIC

APRIL 2, 2024

In the study, post-menopausal women underwent heart scans to assess their CAC score, a measure of plaque buildup—fat, calcium and other substances—in the heart’s arteries. Researchers analyzed data from 579 post-menopausal women who were taking statins to control their cholesterol and had undergone two CAC scans at least one year apart.

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Cardiometabolic Health Congress

NOVEMBER 22, 2024

Another promising advancement is MK-0616 , an oral PCSK9 inhibitor in Phase 3 trials, showing a significant reduction in LDL cholesterol, which provides a more convenient alternative to current injection-based therapies​.

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