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Genetic and Epigenetic Mechanisms Regulating Blood Pressure and Kidney Dysfunction

Hypertension Journal

Dahl established a relationship between kidney, salt, and high blood pressure (BP), which led to the major genetic-based experimental model of hypertension. Hypertension, Ahead of Print. The pioneering work of Dr Lewis K. Genome-wide association studies have identified monogenic and polygenic variants affecting BP in humans.

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Head Up Tilt Test (HUTT)

All About Cardiovascular System and Disorders

Sometimes, head up tilt test, also known in short as HUTT, is also done for the evaluation of postural orthostatic tachycardia syndrome, POTS, a condition in which there is tachycardia on standing up, without a fall in blood pressure. And the basic principle is to observe the heart rate and blood pressure during the procedure.

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Recent Advances in Understanding Peripheral and Gut Immune Cell-Mediated Salt-Sensitive Hypertension and Nephropathy

Hypertension Journal

Hypertension is the primary modifiable risk factor for cardiovascular, renal, and cerebrovascular diseases and is considered the main contributing factor to morbidity and mortality worldwide. Antigen-presenting and adaptive immune cells are implicated in salt-sensitive hypertension and salt-induced renal and vascular injury.

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Lowering Atherosclerotic Cardiovascular Disease Events by Treating Residual Inflammatory Risk

DAIC

Atherosclerotic cardiovascular disease (ASCVD), caused by plaque buildup in arterial walls, is one of the leading causes of disability and death worldwide.1,2 1,2 ASCVD causes or contributes to conditions that include coronary artery disease (CAD), cerebrovascular disease, and peripheral vascular disease (inclusive of aortic aneurysm).3

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Abstract WP289: Insufficient Low-Frequency Blood Pressure Activity Under Orthostatic Stress Predicts Blunted Night-to-Day Blood Pressure Dipping in Patients With Ischemic Cerebrovascular Disease

Stroke Journal

Introduction:Blunted night-to-day blood pressure (BP) dipping was common in ischemic cerebrovascular disease (ICVD). Stroke, Volume 55, Issue Suppl_1 , Page AWP289-AWP289, February 1, 2024. BP dipping could be influenced by baroreflex, which stabilized BP by regulating sympathovagal balance.

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Atherosclerosis and Hippocampal Volumes in Older Adults: The Role of Age and Blood Pressure

Journal of the American Heart Association

Cerebrovascular disease may also be associated with hippocampal volume. Linear regression models examined the association of atherosclerosis and hippocampal to hemisphere volume ratio and whether age at death, blood pressure, and other factors modified associations.

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Dietary antioxidant intake increases ankle brachial pressure index in men but not in women: a cross-sectional study

Frontiers in Cardiovascular Medicine

Objective Atherosclerosis is a significant cause of cardiovascular and cerebrovascular diseases, with a greater impact on men than women. We aimed to investigate the association between dietary composite antioxidant intake and the ankle brachial pressure index (ABPI).