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Windtree’s Istaroxime Scores in Cardiogenic Shock Trial

CardiacWire

Windtree Therapeutics’ istaroxime appears to have scored in its latest Phase 2b trial , showing that the steroidal drug significantly improves systolic blood pressure in cardiogenic shock patients. That could be a big deal in the cardiogenic shock space, which many believe is still in need of more effective treatments.

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Prediction of In?Hospital Mortality for Ischemic Cardiogenic Shock Requiring Venoarterial Extracorporeal Membrane Oxygenation

Journal of the American Heart Association

BackgroundClinical outcome of ischemic cardiogenic shock (CS) requiring extracorporeal membrane oxygenation is highly variable, necessitating appropriate assessment of prognosis. Fifteen parameters were selected to assess in‐hospital mortality. Among 322 patients, 138 (42.9%) survived postdischarge.

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Early Utilization of Mechanical Circulatory Support in Acute Myocardial Infarction Complicated by Cardiogenic Shock: The National Cardiogenic Shock Initiative

Journal of the American Heart Association

BackgroundAcute myocardial infarction complicated by cardiogenic shock (AMI‐CS) is associated with significant morbidity and mortality. The primary end point was in‐hospital mortality. Patients presented with a mean systolic blood pressure of 77.2±19.2 mm Hg, Survival rates to hospital discharge were high.

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Magenta Medical, Developer of World’s Smallest Heart Pump, Closes $105M Financing Round

DAIC

It encompasses devices designed to mechanically unload the failing heart and augment cardiac output in the setting of dangerously low blood pressure, providing a bridge to recovery over a period of hours to days. FDA for two clinical indications: high-risk percutaneous coronary intervention (HR-PCI) and cardiogenic shock (CS).

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Hemodynamic Characteristics and Prognostic Implication of Modified Society for Cardiovascular Angiography and Interventions Shock Classification in Comatose Patients With Out‐of‐Hospital Cardiac Arrest

Journal of the American Heart Association

BackgroundCardiogenic shock complicating acute myocardial infarction is associated with a high mortality rate. Cardiogenic shock after outofhospital cardiac arrest (OHCA) can be due to transient myocardial stunning but also reflect the increasing severity of ongoing heart failure.

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Diffuse Subendocardial Ischemia on the ECG. Left main? 3-vessel disease? No!

Dr. Smith's ECG Blog

The initial blood pressure was 80/palp with a heart rate of 104, respirations 20, oxygen saturations of 94% and a finger stick blood glucose of 268. In addition, the patient received 750 mL of fluid resuscitation with transient improvement of blood pressure. If you can use Doppler, then you can diagnose it.

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How Virtual-First Cardiology is Reshaping the Patient Experience

The Beat Blog

I looked down at the reason for the visit: “blood pressure check.” For the sickest of cardiac patients, those who are leaving the hospital with advanced heart failure or who just had a heart attack, Virtual-First cardiology enables frequent virtual visits driven by AI-driven algorithms which identify the most pressing risks.