Blood Pressure and Cardiac Function - Cardiovascular Update

The Contribution of Declines in Blood Lead Levels to Reductions in Blood Pressure Levels: Longitudinal Evidence in the Strong Heart Family Study

Journal of the American Heart Association

JANUARY 11, 2024

We evaluated whether declines in blood lead were associated with changes in systolic and diastolic blood pressure in adult American Indian participants from the SHFS (Strong Heart Family Study).Methods Methods and ResultsLead in whole blood was measured in 285 SHFS participants in 1997 to 1999 and 2006 to 2009.

Blood Pressure

Blood Pressure Cardiac Function Cardiovascular Disease

Acute Effects of Cannabis Inhalation on Arterial Stiffness, Vascular Endothelial Function, and Cardiac Function

Journal of the American Heart Association

NOVEMBER 22, 2024

Inhalation method did not alter these cannabinoid‐dependent responses.ConclusionsTHC predominant, but not cannabidiol predominant, cannabis elicits increases in heart rate and blood pressure irrespective of inhalation method, which may increase arterial stiffness and reduce diastolic function.

Cardiac Function

Cardiac Function Blood Pressure

Pde5 Inhibition Reduced Blood Pressure and Alleviated Target Organ Damage in Chronic Intermittent Hypoxia

Journal of Cardiovascular Pharmacology

NOVEMBER 22, 2023

Blood pressure was regularly measured during the experiment. Echocardiography was used to estimate cardiac function. Compared to the RA-treated group, the 6-week CIH resulted in a significant increase in blood pressure, altered heart structure and reduced serum cGMP in WT mice.

Blood Pressure

Blood Pressure Cardiac Function Article

Myosin Light Chain Phosphatase Plays an Important Role in Cardiac Fibrosis in a Model of Mineralocorticoid Receptor?Associated Hypertension

Journal of the American Heart Association

FEBRUARY 29, 2024

Our purpose is to investigate the effect of MYPT2 on cardiac function and fibrosis in mineralocorticoid receptor‐related hypertension.Methods and ResultsHL‐1 murine cardiomyocytes were incubated with different concentrations or durations of aldosterone.

Hypertension

Hypertension Blood Pressure Cardiac Function

Windtree’s Istaroxime Scores in Cardiogenic Shock Trial

CardiacWire

SEPTEMBER 25, 2024

Windtree Therapeutics’ istaroxime appears to have scored in its latest Phase 2b trial , showing that the steroidal drug significantly improves systolic blood pressure in cardiogenic shock patients. Showed significant benefits “in many secondary endpoints.”

Cardiogenic Shock

Cardiogenic Shock Blood Pressure Heart Failure Cardiac Function

Association between speckle tracking echocardiography and pressure-volume loops during cardiogenic shock development

Open Heart

MAY 23, 2024

Background The relationship between speckle tracking assessed global longitudinal strain (GLS) and Doppler-based echocardiography with basic physiological markers of cardiac function derived from pressure-volume loops is poorly elucidated. and r 2 =0.49, respectively).

Cardiogenic Shock

Cardiogenic Shock Blood Pressure Cardiac Function Physiology

Case Report: Extended cardiopulmonary resuscitation in sudden cardiac arrest after acute myocardial infarction

Frontiers in Cardiovascular Medicine

AUGUST 8, 2024

We administered adrenaline for cardiac excitation, dopamine for maintained blood pressure, sodium bicarbonate to correct the acidosis, and multiple electric defibrillations. Fortunately, there was no obvious stenosis in the right coronary artery.

Cardiac Arrest

Cardiac Arrest Myocardial Infarction Coronary Artery Bypass Graft Stenosis

Texted from a former EM resident: 70 yo with syncope and hypotension, but no chest pain. Make their eyes roll!

Dr. Smith's ECG Blog

SEPTEMBER 11, 2024

Among patients who present purely for “syncope” — o ur greatest concern is focused on those with a cardiac-related etiology for their syncope — since longterm prognosis is poorest for these patients unless a “fixable” etiology is discovered.

Chest Pain

Chest Pain Aneurysm Stents Stent

Rivus HU6 Shows Obesity-HFpEF Potential

CardiacWire

AUGUST 14, 2024

Perhaps more importantly , the HU6 group achieved a range of obesity and HF-related secondary endpoints, including exercise capacity, quality of life, body composition, cardiac function/structure, and cardiometabolic dysfunction markers (e.g. blood pressure, pulse, glucose control, inflammation, lipid levels, and liver enzymes).

Obesity

Obesity Diet Quality of Life Blood Pressure

Medications for Congenital Heart Disease: What Every Parent Should Know

Conquering CHD

JUNE 20, 2023

Blocking this enzyme helps relax blood vessels so there is a wider opening for better blood flow. This will lower blood pressure, making it easier for the heart to pump. POTENTIAL SIDE EFFECTS: Potential adverse reactions include coughing, dizziness, kidney problems, and low blood pressure.

Congenital Heart Disease

Congenital Heart Disease Congenital Heart Disease ACE Inhibitor

Orthostatic hypotension onset after invasive procedure?

Dr. Smith's ECG Blog

JANUARY 13, 2024

If it does not sense a native rhythm (perhaps from lead fracture or displacement), it will attempt to pace at 60 beats per minute, which can cause unnecessary pacing spikes interrupting normal cardiac function. A week after discharge the patient fell again, blood pressure was reported as 73/62. The case continues.

Pacemaker

Pacemaker Bicuspid/Mitral Blood Pressure Bradycardia

What are treatment options for this rhythm, when all else fails?

Dr. Smith's ECG Blog

JULY 21, 2024

Immediately after contrast injection into the LMCA, the patient had circulatory collapse, with a precipitous drop in blood pressure. An Impella device was placed to maintain cardiac output and perfusion pressures. Cardiac function is poor, with akinesis of the LAD territory. Epinephrine infusion was begun.

Arrhythmia

Arrhythmia Cardiogenic Shock Bradycardia Defibrillator

Association between locomotor muscle quality and cardiac function during exercise in heart failure with preserved ejection fraction

European Journal of Heart Failure

NOVEMBER 19, 2024

Muscle quality and cardiac function in heart failure with preserved ejection fraction (HFpEF) during exercise. Abstract Aims Muscle quality (MQ) is used to assess skeletal muscle function; however, the relationship between MQ and cardiac function during exercise in heart failure with preserved ejection fraction (HFpEF) is unknown.

Preserved Ejection Fraction

Preserved Ejection Fraction Cardiac Function Exercise Heart Failure

Cardiac remodeling in elite young Asian female soccer players

Frontiers in Cardiovascular Medicine

NOVEMBER 14, 2024

Given that soccer is a common sport, evaluation of cardiac function in soccer players is important; however, few studies have analyzed adolescent soccer players. Participants provided physical examination data such as height, weight, blood pressure, and pulse, along with echocardiographic results.

Blood Pressure

Blood Pressure Cardiac Function

Comprehensive strain assessment and mortality after acute myocardial infarction: a retrospective observational study based on the Essen Coronary Artery Disease registry

Heart BMJ

NOVEMBER 25, 2024

Background and aims Current ESC guidelines on the management of patients after acute myocardial infarction only include the evaluation of left ventricular (LV) function by assessment of the ejection fraction in addition to clinical risk scores to estimate the patient’s prognosis. Results During a median follow-up of 1.5 (0.5–4.2)

Myocardial Infarction

Myocardial Infarction Coronary Artery Disease Blood Pressure Tricuspid

Effects of different doses of remimazolam on the quality of sedation and cardiac function in elderly patients: a double-blind randomised controlled study

Frontiers in Cardiovascular Medicine

JANUARY 6, 2025

BackgroundWe intended to observe the effects of different doses of remimazolam besylate via intravenous induction on the quality of sedation and cardiac function in elderly patients.MethodsA total of 135 ASA IIII patients undergoing elective laparoscopic cholecystectomy were selected. There were 45 patients in each group.

Cardiac Function

Cardiac Function Blood Pressure Stroke Strokes

The Contribution of Declines in Blood Lead Levels to Reductions in Blood Pressure Levels: Longitudinal Evidence in the Strong Heart Family Study

Acute Effects of Cannabis Inhalation on Arterial Stiffness, Vascular Endothelial Function, and Cardiac Function

Pde5 Inhibition Reduced Blood Pressure and Alleviated Target Organ Damage in Chronic Intermittent Hypoxia

Myosin Light Chain Phosphatase Plays an Important Role in Cardiac Fibrosis in a Model of Mineralocorticoid Receptor?Associated Hypertension

Windtree’s Istaroxime Scores in Cardiogenic Shock Trial

Association between speckle tracking echocardiography and pressure-volume loops during cardiogenic shock development

Case Report: Extended cardiopulmonary resuscitation in sudden cardiac arrest after acute myocardial infarction

Texted from a former EM resident: 70 yo with syncope and hypotension, but no chest pain. Make their eyes roll!

Rivus HU6 Shows Obesity-HFpEF Potential

Medications for Congenital Heart Disease: What Every Parent Should Know

Orthostatic hypotension onset after invasive procedure?

What are treatment options for this rhythm, when all else fails?

Association between locomotor muscle quality and cardiac function during exercise in heart failure with preserved ejection fraction

Cardiac remodeling in elite young Asian female soccer players

Comprehensive strain assessment and mortality after acute myocardial infarction: a retrospective observational study based on the Essen Coronary Artery Disease registry

Effects of different doses of remimazolam on the quality of sedation and cardiac function in elderly patients: a double-blind randomised controlled study

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