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2024’s Mid-Year Review: FDA-Approved Cardiorenal Metabolic Drugs and Devices 

Cardiometabolic Health Congress

Aprocitentan (Tryvio) Approved: March 20, 2024 Indication: Hypertension in adults Administration: Oral Mechanism: Endothelin A and B receptor antagonist Developer: Idorsia Pharmaceuticals Significance: First and only FDA-approved endothelin receptor antagonist for high blood pressure that remains uncontrolled with existing treatments.

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Physiology Friday #196: Resistance Training and Heart Health

Physiologically Speaking

Blood glucose control Resistance exercise training can reduce fasting glucose by 2–5 mg/dL in adults with prediabetes and type 2 diabetes but doesn’t seem to reduce blood glucose in healthy adults (not surprising). RT Prescription Resistance training need not be complicated to be effective.

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Physiology Friday #196: Resistance Training and Heart Health

Physiologically Speaking

Blood glucose control Resistance exercise training can reduce fasting glucose by 2–5 mg/dL in adults with prediabetes and type 2 diabetes but doesn’t seem to reduce blood glucose in healthy adults (not surprising). RT Prescription Resistance training need not be complicated to be effective.