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High Blood Pressure (Hypertension) Persistent high blood pressure forces the heart to work harder to pump blood. Over time, this additional strain causes the heart muscle to thicken, enlarging the heart. Diuretics , which help remove excess fluid from the body, easing the heart’s workload.
As an alternative therapeutic option, LVAD heart pumps have been implanted to help patients with end-stage heart failure sustain bloodcirculation in the body. However, there are shortcomings associated with LVAD implantation: complications include infection, bloodclotting (thrombosis), stroke and bleeding.
This can lead to damage of the inner lining of the heart in that region. A bloodclot can form on the inner surface of the heart as a consequence. These clots can break away into the circulation and get lodged into a blood vessel of the brain. Another reason for stroke is high blood pressure.
The well known pro-coagulant state of pregnancy is an evolutionary protective process to make bloodclot quicker, to save fetal loss in early pregnancy and mitigate postpartum bleeding. Cardiomyopathy Finally most importantly prosthetic heartvalves & other Intra cardiac devices. J Am Coll Cardiol. PMID: 10334435.
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