Stroke Journal

FEBRUARY 7, 2024

Stroke, Ahead of Print. Background:Blood-based biomarkers have the potential to reflect cerebrovascular signaling after microvascular injury; yet, the detection of cell-specific signaling has proven challenging. Microvesicles retain parental cell surface antigens allowing detection of cell-specific signaling encoded in their cargo.

Biomarkers 40

Biomarkers Strokes Stroke 40

DAIC

DECEMBER 13, 2023

MILLER, PHD, LED THE DEVELOPMENT OF A NEW "ATHEROSCLEROSIS ATLAS" THAT DETAILS, AT THE LEVEL OF INDIVIDUAL CELLS, CRITICAL PROCESSES RESPONSIBLE FOR FORMING THE HARMFUL PLAQUE BUILDUP THAT CAUSES HEART ATTACKS, STROKES AND CORONARY ARTERY DISEASE. When they break loose, they can be deadly, triggering strokes and heart attacks.

Heart Attack 105

Heart Attack Heart attacks Atherosclerosis Strokes 105

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP283-ATP283, February 1, 2024. Objectives:The dynamic evolution of ischemic penumbra to core has implications for stroke outcomes. Serum H3K18la variations emerge as potential indicators of neuronal damage severity, suggesting effective biomarkers for assessing post-stroke prognosis.

Biomarkers 40

Biomarkers Strokes Stroke Outcomes 40

Medical Xpress - Cardiology

SEPTEMBER 3, 2024

Mass screening for atrial fibrillation using ECG together with heart failure biomarker does not prevent ischemic stroke or systemic embolism (blood clot) in older adults aged 75–76 years over 5 years follow-up, according to late breaking research presented in a Hot Line Session at this year's ESC Congress 2024 in London, UK (30 Aug–2 Sept).

Atrial Fibrillation 40

Atrial Fibrillation Blood Clot Research Strokes 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page A106-A106, February 1, 2024. Background:Circulating interleukin-6 (IL-6) concentrations are elevated in acute stroke but the timing of the IL-6 response in humans is unknown. We used a mobile stroke unit (MSU) to identify IL-6 levels within minutes of symptom onset. pg/mL, respectively.

Strokes 40

Strokes Stroke Thrombolysis Circulation 40

Circulation

NOVEMBER 11, 2024

Background:Following an ischemic stroke, a serious complication known as hemorrhagic transformation (HT) might jeopardize patient outcomes. Following an ischemic stroke, an increased incidence of HT, especially parenchymal hematoma (PH), has been associated with greater NLR.

Hemorrhage 40

Hemorrhage Strokes Stroke Myocardial Infarction 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATMP9-ATMP9, February 1, 2024. Background:FLAIR vascular hyperintensities (FVH) are high signal intensities on MRI resulting from sluggish flow through collateral vessels in patients with acute arterial ischemic stroke (AIS). Data from adults suggest they may be a marker of penumbra.

Pediatrics 40

Pediatrics Strokes Stroke Biomarkers 40

Journal of the American Heart Association

NOVEMBER 28, 2023

BackgroundComplex aortic plaque (CAP) is a potential embolic source in patients with cryptogenic stroke (CS). From 2293 studies, 45 were reviewed for CAP imaging biomarker criteria in patients with acute CS (N=37 TEE; N=9 CTA; N=6 magnetic resonance imaging). The most common CAP imaging biomarker was ≥4 mm plaque thickness.

Plaque 40

Plaque Biomarkers Aortic Strokes 40

DAIC

FEBRUARY 1, 2024

February 1, 2024 — As cardiologists, heart disease patients and the organizations that serve them across the country embark on American Heart Month, DAIC has compiled a snapshot of significant cardiovascular disease (CVD) and stroke statistics, along with a review of the atherosclerosis drug market. per 1,000* - 122.4

Cardiovascular Disease 104

Cardiovascular Disease Strokes Stroke Atherosclerosis 104

Cardiovascular Diabetology

DECEMBER 12, 2023

This study aimed to evaluate the association of triglyceride-glucose (TyG) index, an insulin resistance surrogate biomarker, with first stroke in a hypertensive population and to explore potential influencing.

Hypertension 52

Hypertension Strokes Stroke Biomarkers 52

HeartRhythm

APRIL 30, 2024

Stroke continues to be a leading cause of death worldwide despite improvements in prevention and treatment. Novel biomarkers have been proposed to improve the accuracy of stroke risk assessment including electrocardiographic (ECG)-age, which has been shown to predict clinical outcomes.

Strokes 40

Strokes Stroke Biomarkers Outcomes 40

Stroke Journal

MARCH 24, 2024

Stroke, Volume 55, Issue 4 , Page 801-811, April 1, 2024. This review highlights pathways that are aiding the search for sensitive and specific blood-based cerebrovascular dysfunction markers, describes promising candidates, and explains ongoing initiatives to discover blood-based VCID biomarkers.

Biomarkers 40

Biomarkers Dementia Hemorrhage Research 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATMP58-ATMP58, February 1, 2024. Objectives:To determine the relationship between patient-reported outcome measures (PROMs) and volumetric biomarkers assessed on clinical imaging in acute ischemic stroke (AIS).Background:AIS Background:AIS is a leading cause of long-term disability.

Strokes 40

Strokes Stroke Outcomes Biomarkers 40

Stroke Journal

DECEMBER 14, 2023

Stroke, Ahead of Print. BACKGROUND:Iron status has been associated with functional outcomes after ischemic stroke (IS). This data set included 4 iron status biomarkers, namely, ferritin, total iron binding capacity, iron, and transferrin saturation (TSAT). Nonetheless, this association may be affected by confounders.

Outcomes 40

Outcomes Strokes Stroke Biomarkers 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

Stroke: Vascular and Interventional Neurology, Volume 3, Issue S2 , November 1, 2023. This secondary study aims to describe the association between the N20 response and imaging biomarkers of ischemic penumbra, infarct volume and collateral flow.MethodsPresence and amplitude of the N20 response was recorded before EVT.

Biomarkers 40

Biomarkers Strokes Stroke Outcomes 40

Stroke Journal

MARCH 6, 2024

Stroke, Ahead of Print. Vascular cognitive impairment is common after stroke, in memory clinics, medicine for the elderly services, and undiagnosed in the community. Neuroimaging has a major role in identifying the proportion of vascular versus other likely pathologies in patients with cognitive impairment.

Biomarkers 40

Biomarkers Dementia Strokes Stroke 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP24-ATP24, February 1, 2024. Background:Post-stroke depression (PSD) is a common neuropsychiatric complication of stroke associated with poor functional outcome and increased mortality. versus 40.7%). to 0.25), p<0.001], and Hcy [SMD 0.14, (95% CI 0.05 to 0.22), p<0.001].

Strokes 40

Strokes Stroke Biomarkers Diabetes 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWP266-AWP266, February 1, 2024. Background:This population-based study investigated the potential of machine learning algorithms to predict stroke incidence and identify important risk factors. These clusters were categorized into high-, medium-, and low-risk groups.

Strokes 40

Strokes Stroke Blood Pressure Laboratory 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

Stroke: Vascular and Interventional Neurology, Volume 3, Issue S2 , November 1, 2023. IntroductionThe routinely used computed tomography (CT)‐based workup in the setting of acute ischemic stroke (AIS) includes non‐contrast brain CT, CT angiography (CTA), and CT perfusion.

Hemorrhage 40

Hemorrhage Strokes Stroke Biomarkers 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP150-ATP150, February 1, 2024. Introduction:Ischemic stroke is a leading cause of death and disability in the US, with 20-40% of cases, classified as cryptogenic or with an unexplained cause. Stroke in multiple vascular territories MVT was present in 22/101 (22%) at baseline.

Atrial Fibrillation 40

Atrial Fibrillation Strokes Stroke Biomarkers 40

Frontiers in Cardiovascular Medicine

APRIL 24, 2024

The early detection of plaques by circulating biomarkers is highly clinically relevant to prevent the occurrence of major complications such as stroke or heart attacks. BackgroundAtherosclerosis is a widespread disorder of the cardiovascular system.

Plaque 52

Plaque Biomarkers Circulation Stenosis 52

Medical Xpress - Cardiology

MAY 1, 2024

A simple blood test could allow doctors to determine whether a person may be at higher risk for stroke or cognitive decline during their lifetime, according to a new UCLA Health study.

Cerebrovascular Disease 94

Cerebrovascular Disease Biomarkers Strokes Stroke 94

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWMP117-AWMP117, February 1, 2024. Background:Stroke is a significant health issue in the United States, and identifying biomarkers for preventing acute ischemic stroke (AIS) remains the highest priority. Exosomal miR-9-3p showed a 14.7-fold

Strokes 40

Strokes Stroke Biomarkers 40

Stroke Journal

MARCH 6, 2024

Stroke, Ahead of Print. BACKGROUND:The temporal ordering of biomarkers for cerebral amyloid angiopathy (CAA) is important for their use in trials and for the understanding of the pathological cascade of CAA.

Biomarkers 40

Biomarkers Hemorrhage Strokes Stroke 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATMP25-ATMP25, February 1, 2024. Background:Acute brain injuries, including aneurysmal subarachnoid hemorrhage (aSAH), ischemic stroke (IS), and traumatic brain injury (TBI), entail complex recovery processes involving brain plasticity and synaptic regeneration mechanisms.

Biomarkers 40

Biomarkers Outcomes Aneurysm Hemorrhage 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP238-ATP238, February 1, 2024. Both subjects with stroke and subjects with TIA had increased serum PDGFRβ compared to those without history of CVA (6608.4 No significant differences related to PDGFRβ were observed between subjects with stroke vs. TIA (P=0.25). pg/mL and 5337.0

Strokes 40

Strokes Stroke Dementia Biomarkers 40

Stroke Journal

MARCH 24, 2024

Stroke, Volume 55, Issue 4 , Page e131-e131, April 1, 2024.

Strokes 40

Strokes Stroke Biomarkers 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page A131-A131, February 1, 2024. The primary outcome was incident ischemic stroke. There were a total of 18 ischemic stroke events among those with LVI (6%) and 65 among those without LVI (3%). LV apical circumferential strain>-10% may be a novel and quantitative stroke risk factor.

Atherosclerosis 40

Atherosclerosis Strokes Stroke Atrial Fibrillation 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWP150-AWP150, February 1, 2024. Dual antiplatelet therapy (DAPT) with aspirin and clopidogrel is standard of care for secondary prevention in non-cardioembolic minor acute ischemic stroke (AIS) and high-risk transient ischemic attack (TIA). 95% CI +30.71 to +176.1;

Strokes 40

Strokes Stroke Biomarkers Outcomes 40

Journal of the American Heart Association

JANUARY 19, 2024

BackgroundPatients with acute ischemic stroke and active cancer have more severe neurological symptoms, elevated risks of stroke recurrence, and death compared with the general population. We observed no significant difference in the rate of stroke recurrence within 1 year between the groups. 30.78];P<0.05).ConclusionsElevated

Cancer 40

Cancer Strokes Stroke Outcomes 40

Open Heart

NOVEMBER 9, 2024

Objective To evaluate the impact of intraoperative neuromonitoring (IONM) on stroke and operative mortality after coronary and/or valvular operations. Propensity-score matching was employed to assess the association of IONM usage with operative mortality and stroke. vs 2.5%) and stroke (4.9% for stroke. for stroke.

Cerebrovascular Disease 52

Cerebrovascular Disease Strokes Stroke Biomarkers 52

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWMP8-AWMP8, February 1, 2024. Introduction:Thrombolysis in acute ischemic stroke (AIS) using Tenecteplase (TNK) is gaining popularity compared to Alteplase (ALT) for its practical advantages. The baseline demographics, vascular risk factors, and admission stroke severity were similar.

Strokes 40

Strokes Stroke Thrombolysis Biomarkers 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWP292-AWP292, February 1, 2024. Introduction:Sleep debt attenuates nitric oxide synthase 3 (NOS3) activity and vasodilation which could diminish brain tissue oxygen (PbtO2) after stroke. S-nitrosylatedβHb-Cys93promotes hypoxic vasodilation to enhance PbtO2.

Strokes 40

Strokes Stroke Biomarkers 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page A130-A130, February 1, 2024.

Biomarkers 40

Biomarkers Strokes Stroke Physiology 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

Stroke: Vascular and Interventional Neurology, Volume 3, Issue S2 , November 1, 2023. IntroductionLoss of autoregulation after endovascular therapy (EVT) for large‐artery acute ischemic stroke (AIS) is well documented. [1] Further studies are required to clarify the utility of this biomarker in guiding post‐EVT care.

Strokes 40

Strokes Stroke Blood Pressure Document 40

Cardiovascular Diabetology

JUNE 20, 2024

Circulating atherogenic index of plasma (AIP) levels has been proposed as a novel biomarker for dyslipidemia and as a predictor of insulin resistance (IR) risk. However, the association between AIP and the inc.

Biomarkers 52

Biomarkers Circulation Strokes Stroke 52

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page A133-A133, February 1, 2024. Mendelian randomization (MR) studies suggest a causal effect of Fe status on ischemic stroke (IS).

BMI 40

BMI Strokes Stroke Risk Factors 40