HCPLive

SEPTEMBER 8, 2024

Investigators analyzed levels of CXCL10, MMP3, S100A8, ACP5, and CCL2 in patients treated with biologics and methotrexate.

Biomarkers 98

Biomarkers Research 98

Frontiers in Cardiovascular Medicine

APRIL 14, 2025

Conventional biomarkers, while effective for a number of patient groups, fail to provide personalized diagnosis and prognosis, necessitating the exploration of novel markers. Recent attention has turned to a subset of cfDNA, circulating bacterial DNA (cbDNA), derived from gut microbiota, as a potential biomarker.

Cardiovascular Disease 52

Cardiovascular Disease Circulation Biomarkers Risk Factors 52

Science Daily - Heart Disease

MARCH 18, 2024

Researchers have identified novel protein biomarkers that are associated with the development of CHD in people with and without diabetes. Coronary heart disease is a major global health problem, especially among people with type 2 diabetes.

Biomarkers 76

Biomarkers Heart Disease Diabetes Research 76

HCPLive

FEBRUARY 19, 2024

In this Lungcast segment, Spicer spoke on several treatment-specific biomarkers for lung cancer and discussed the future of lung cancer therapy.

Biomarkers 69

Biomarkers Cancer Research 69

Science Daily - Heart Disease

MAY 7, 2024

Researchers have discovered a protein marker to help identify cells able to repopulate in patients with damaged blood vessels.

Coronary Artery Disease 104

Coronary Artery Disease Biomarkers Heart attacks Heart Attack 104

Med Page Today

NOVEMBER 11, 2024

(MedPage Today) -- A small panel of circulating biomarkers may reliably distinguish hypertrophic cardiomyopathy (HCM) from similar conditions that cause left ventricular hypertrophy (LVH), researchers found. From proteomic profiling of nearly.

Cardiomyopathy 116

Cardiomyopathy Biomarkers Circulation Research 116

Frontiers in Cardiovascular Medicine

APRIL 8, 2025

Here, biomarkers related to energy metabolism in HCM were identified through bioinformatics analysis.MethodsHCM transcriptome data were acquired from the GEO (GSE36961) database for comparative analysis in order to identify differentially expressed genes (DEGs). GATA2 was also found to be a TF regulating the expression of both biomarkers.

Biomarkers 52

Biomarkers Cardiomyopathy Research 52

Stroke Journal

MARCH 14, 2025

As personalized medicine progresses, the development of reliable biomarkers, such as the candidate biomarker VEGF for AVMs and CCMs, will be crucial for guiding treatment decisions. Due to the genetic overlap, these advancements may also offer future therapeutic strategies for intracranial aneurysms.

Hemorrhage 58

Hemorrhage Aneurysm Strokes Stroke 58

DAIC

MARCH 6, 2024

a biomarker-guided predictive care company, has presented data showing its FDA-cleared, non-invasive, biomarker-based technology for remote heart failure monitoring detected twice as many heart failure events as compared to the weight-based standard of care. Bodyport Inc., Image courtesy: Bodyport Inc. Image courtesy: Bodyport Inc.

Heart Failure 128

Heart Failure Technology Biomarkers Hospital 128

Frontiers in Cardiovascular Medicine

APRIL 21, 2025

Machine learning models, including Random Forest and Support Vector Machine (SVM), were applied to select potential AF-related diagnostic biomarkers, and validated in the animal model (beagles; n=6).ResultsA Correlation analysis and WGCNA were performed to assess interactions between lactylation-related genes and immune-associated DEGs.

Atrial Fibrillation 52

Atrial Fibrillation Biomarkers Heart Failure Arrhythmia 52

Becker's Hospital Review - Cardiology

JANUARY 3, 2024

Dallas-based UT Southwestern Medical Center researchers found a two-step screening protocol combining clinical risk assessment with biomarker testing that can identify which patients with Type 2 diabetes need medication to prevent heart failure.

Heart Failure 110

Heart Failure Diabetes Biomarkers Research 110

HCPLive

AUGUST 16, 2024

Strnad explains the need for noninvasive biomarkers in AATD liver disease and early research about circulating Z-polymer’s potential association with clinically relevant adverse outcomes.

Biomarkers 52

Biomarkers Circulation Research Outcomes 52

Cardiovascular Diabetology

APRIL 14, 2025

The associations between systemic inflammation biomarkers and cardiovascular disease (CVD) remain not well explored. This study aimed to investigate associations between different systemic inflammation biomark.

Biomarkers 52

Biomarkers Cardiovascular Disease Research 52

Frontiers in Cardiovascular Medicine

FEBRUARY 17, 2025

Research on miRNAs also faces issues like inconsistent measurement techniques and unclear miRNA-target gene relationships. Moreover, the translation of miRNA-based research into clinical applications is hindered by problems related to miRNA stability, delivery mechanisms, off-target effects, and long-term safety.

Article 52

Article Research Biomarkers 52

Frontiers in Cardiovascular Medicine

JANUARY 2, 2024

Artificial intelligence (AI) has emerged as a promising field in cardiovascular disease (CVD) research, offering innovative approaches to enhance diagnosis, treatment, and patient outcomes. In this study, we conducted bibliometric analysis combined with topic modeling to provide a comprehensive overview of the AI research landscape in CVD.

Research 64

Research Cardiovascular Disease Biomarkers Innovation 64

Becker's Hospital Review - Cardiology

MAY 29, 2024

Using artificial intelligence in angiogram analysis can broaden diagnostic abilities and improve clinical decision-making, according to new research presented May 2 in Long Beach, Calif., at the Society for Cardiovascular Angiography and Interventions' Scientific Sessions 2024.

Biomarkers 64

Biomarkers Research 64

Frontiers in Cardiovascular Medicine

MARCH 13, 2025

Recent research has significantly advanced our understanding of RHD, shedding light on the immune-to-autoimmune transition, neoangiogenesis, and lymphangiogenesis processes. However, over the past two decades, there has been a revival of scientific interest, fostering optimism for the future.

Heart Valves 52

Heart Valves Bicuspid/Mitral Biomarkers Heart Disease 52

Cardiovascular Diabetology

MARCH 19, 2025

This study aims to identify early metabolomic biomarkers of gestational diabetes mellitus (GDM) and evaluate their association with hepatic steatosis.

Biomarkers 52

Biomarkers Diabetes Research 52

DAIC

APRIL 9, 2024

The PROACT study reported no impact on cardiotoxicity biomarkers or secondary endpoints related to heart function among patients who took high doses of enalapril, an ACE inhibitor, along with high doses of anthracyclines. of those who received enalapril and 83.3% of those receiving standard of care.

ACE Inhibitor 105

ACE Inhibitor Cancer Biomarkers Heart Failure 105

Physiologically Speaking

JULY 24, 2024

Andrew is a research scientist at Sansum Diabetes Research Institute, where he’s investigating metabolic therapies for health and disease. Today’s interview is with Andrew Koutnik, Ph.D. His mission is to optimize metabolic health and patient outcomes for people living with type 1 diabetes. You can check those out below.

Diabetes 115

Diabetes Diet Physiology Biomarkers 115

Stroke Journal

MARCH 24, 2024

While researchers in the Alzheimer disease field have been working for years to establish and test blood-based biomarkers for Alzheimer disease diagnosis, prognosis, clinical therapy discovery, and early detection, blood-based biomarkers for VCID are in their infancy and also face challenges.

Biomarkers 40

Biomarkers Dementia Hemorrhage Research 40

Cardiovascular Diabetology

MAY 6, 2024

The association between iron biomarkers and cardiovascular disease risk factors (CVD-RFs) remains unclear. We aimed to (1) evaluate the cross-sectional and longitudinal associations between iron biomarkers (se.

Risk Factors 52

Risk Factors Biomarkers Cardiovascular Disease Research 52

Frontiers in Cardiovascular Medicine

FEBRUARY 10, 2025

Given the pivotal role of inflammatory mediators in the pathogenesis of aortic calcification, inflammation has attracted interest as a peripheral biomarker for early mortality prediction in patients with aortic calcification. However, further research is required to confirm this association.

Aortic 52

Aortic Atherosclerosis Laboratory Biomarkers 52

Medical Xpress - Cardiology

JANUARY 2, 2024

A two-step screening protocol that combines clinical risk assessment with biomarker testing can more effectively identify which patients with type 2 diabetes need medication to prevent heart failure, according to a study led by UT Southwestern Medical Center researchers.

Heart Failure 80

Heart Failure Diabetes Biomarkers Research 80

Frontiers in Cardiovascular Medicine

FEBRUARY 25, 2025

The results of the GeneMANIA online database showed that the two biomarkers, BBPB and CXCL1, mainly had functional interactions with cytokine activity, chemokine receptor activity, cell response to chemokines, neutrophil migration, response to chemokines, granulocyte chemotaxis, and granulocyte migration. Based on AUC >0.7,

Kidney Disease 52

Kidney Disease Atrial Fibrillation Biomarkers Download 52

Medical Xpress - Cardiology

OCTOBER 28, 2024

Single ventricle heart diseases (SVHDs), the most severe type of congenital heart disease, requires immediate treatment after birth. A growing number of fetal therapies make the benefits of early diagnosis even more important.

Congenital Heart Disease 40

Congenital Heart Disease Congenital Heart Disease Biomarkers 40

Cardiovascular Diabetology

NOVEMBER 1, 2024

Dysglycemia and insulin resistance increase type 2 diabetes (T2D) and cardiovascular disease (CVD) risk, yet associations with specific glucose-insulin homeostatic biomarkers have been inconsistent. Vitamin D.

Cardiovascular Disease 52

Cardiovascular Disease Biomarkers Diabetes Research 52

Medical Xpress - Cardiology

SEPTEMBER 3, 2024

Mass screening for atrial fibrillation using ECG together with heart failure biomarker does not prevent ischemic stroke or systemic embolism (blood clot) in older adults aged 75–76 years over 5 years follow-up, according to late breaking research presented in a Hot Line Session at this year's ESC Congress 2024 in London, UK (30 Aug–2 Sept).

Atrial Fibrillation 40

Atrial Fibrillation Blood Clot Research Strokes 40

Medical Xpress - Cardiology

FEBRUARY 20, 2025

Researchers from the Bellvitge Biomedical Research Institute (IDIBELL) and the Germans Trias i Pujol Research Institute (IGTP) have studied variations in mRNA length during the progression of atherosclerosis in a mouse model.

Atherosclerosis 59

Atherosclerosis Biomarkers Research 59

Journal of Clinical Investigation - Cardiology

JANUARY 16, 2024

This work was supported by grants from the Ernest and Bonnie Beutler Research Program of Excellence in Genomic Medicine, The Israel Science Foundation, the Waldholtz/Pakula family, the Robert M. CONCLUSION. and Marilyn Sternberg Family Charitable Foundation and the Helmsley Charitable Trust (to YD).

Biomarkers 68

Biomarkers Transplant Circulation Research 68

Journal of Clinical Investigation - Cardiology

JUNE 17, 2024

These results show promising potential for examining crizanlizumab in larger studies of RVCL-S and similar small-vessel diseases and for using the retina as a biomarker for systemic disease.Trial registration ClinicalTrials.gov NCT04611880.FUNDING FUNDING The Clayco Foundation; DeNardo Education and Research Foundation Grant; Jeffrey T.

Biomarkers 92

Biomarkers Research Innovation Education 92

HCPLive

FEBRUARY 12, 2024

The prominent clinical investigator joins to discuss adjuvant and neoadjuvant care research, as well as the application of biomarkers in personalized care.

Cancer 64

Cancer Biomarkers Research 64

Cardiovascular Diabetology

MARCH 20, 2025

The triglyceride-glucose index serves as a dependable biomarker for gauging insulin resistance linked to cardiovascular disease. Our study was designed to investigate how the trajectory of the triglyceride-glu.

Heart Failure 86

Heart Failure Biomarkers Cardiovascular Disease Diabetes 86

Frontiers in Cardiovascular Medicine

DECEMBER 5, 2024

This study aimed to identify CHD-associated biomarkers using transcriptomic data.MethodsThis study examined 74 efferocytosis-related genes (ERGs) and 17 M1 macrophage polarization-related genes (MRGs) across two CHD-relevant datasets, GSE113079 and GSE42148. BackgroundMacrophage polarization and efferocytosis have been implicated in CHD.

Biomarkers 40

Biomarkers Heart Disease Research 40

Stroke Journal

JANUARY 30, 2025

We conducted internal validation on the same samples using the PeptiQuant Plus biomarker assessment kits (BAK-270) for targeted protein quantitation (Figure 1).Results:We For multigroup comparisons, we performed feature selection by sparse partial least squares discriminant analysis (sPLS-DA) using the mixOmics R package.

Biomarkers 40

Biomarkers Strokes Stroke Hemorrhage 40

Coronary Artery Disease Journal

DECEMBER 2, 2024

Cortisol is a biomarker associated with stress. We sought to assess stress contribution to AMI using hair cortisol concentration (HCCs) as a surrogate biomarker. Background Chronic stress is believed to play a role in the pathophysiology of acute myocardial infarction (AMI).

Myocardial Infarction 40

Myocardial Infarction Biomarkers BMI Laboratory 40

Stroke Journal

FEBRUARY 1, 2024

The LDA equation combining eight biomarkers was: -0.239[LPC17:0] - 1.125[TAG51:2:FA15:0] + [TAG51:2:FA18:1] + [D-glucuronic Acid] + 0.416[hsa-miR-146b-3p] + 0.082[hsa-miR-485-3p] + 0.433[hsa-miR-5010-5p] + 0.727[hsa-miR-485-5p], effectively predicting favorable outcomes.

Biomarkers 40

Biomarkers Outcomes Aneurysm Hemorrhage 40