DAIC

DECEMBER 13, 2023

MILLER, PHD, LED THE DEVELOPMENT OF A NEW "ATHEROSCLEROSIS ATLAS" THAT DETAILS, AT THE LEVEL OF INDIVIDUAL CELLS, CRITICAL PROCESSES RESPONSIBLE FOR FORMING THE HARMFUL PLAQUE BUILDUP THAT CAUSES HEART ATTACKS, STROKES AND CORONARY ARTERY DISEASE. Over time, fatty plaques build up inside the arteries, where they can slow blood flow.

Heart attacks 105

Heart attacks Heart Attack Atherosclerosis Strokes 105

Frontiers in Cardiovascular Medicine

MARCH 4, 2024

The complex development of atherosclerosis manifests as intimal plaque which occurs in the presence or absence of traditional risk factors. Atherosclerotic coronary artery disease (CAD) is the causal pathological process driving most major adverse cardiovascular events (MACE) worldwide.

Plaque 59

Plaque Coronary Artery Disease Blood Pressure Cardiovascular Disease 59

Stroke Journal

JANUARY 30, 2025

Advancements in magnetic resonance angiography (MRA) with vessel wall imaging (VWI) have enabled the identification of vulnerable plaques, aiding in risk stratification for neurovascular events. Eleven plaques were vulnerable in preoperative MRI with VWI. There were 73.3% male patients. of patients had symptomatic disease.

Plaque 40

Plaque Biomarkers Strokes Stroke 40

DAIC

JUNE 4, 2024

I am excited about the potential of the FAI-Score biomarker, which has promising prognostic value beyond existing CT-based methods such as plaque, calcium scoring, and CAD-RADS based interpretation." Details of the study, included in a written statement issued by Caristo Diagnostics, follow.

Technology 116

Technology Heart attacks Heart Attack Coronary Artery Disease 116

DAIC

FEBRUARY 3, 2025

This clearance comes in advance of disease-modifying therapies on the horizon expected to help clinicians use this biomarker to guide patients to improved cardiovascular health, saidBrad Moore, president and CEO at Roche Diagnostics North America. The development of the Tina-quant Lipoprotein (a) Gen.2

Cardiovascular Disease 52

Cardiovascular Disease Aortic valve Biomarkers Innovation 52

Frontiers in Cardiovascular Medicine

FEBRUARY 20, 2024

We investigated whether treatment with LDE-paclitaxel changes plaque progression by coronary CT angiography and is safe in patients with chronic coronary artery disease. Analysis of inflammatory biomarkers and coronary CTA was also performed at baseline and 4 weeks after treatment.

Coronary Artery Disease 59

Coronary Artery Disease Laboratory Plaque Myocardial Infarction 59

Circulation

NOVEMBER 11, 2024

Introduction/Background:According to the American Heart Association, the accumulation of plaque in the walls of arteries is identified as the primary cause of atherosclerotic cardiovascular disease (ASCVD). Circulation, Volume 150, Issue Suppl_1 , Page A4146638-A4146638, November 12, 2024.

Biomarkers 40

Biomarkers Cardiovascular Disease Laboratory Plaque 40

All About Cardiovascular System and Disorders

MARCH 7, 2024

Detailed analysis of the excised carotid plaques were carried out with pyrolysis-gas chromatography-mass spectrometry, stable isotope analysis, and electron microscopy. Inflammatory biomarkers were also estimated. Comparison was with those who had no evidence of these plastics in the plaques.

Plaque 52

Plaque Myocardial Infarction Laboratory Cardiac Function 52

Circulation

JANUARY 15, 2024

Nevertheless, the relationship between CAC and the susceptibility of a plaque to provoke a thrombotic event remains incompletely understood. This review summarizes the current understanding and literature on CAC.

Coronary Artery Disease 45

Coronary Artery Disease Atherosclerosis Laboratory Plaque 45

DAIC

JANUARY 23, 2024

Atherosclerotic cardiovascular disease (ASCVD), caused by plaque buildup in arterial walls, is one of the leading causes of disability and death worldwide.1,2 7 Research has shown inflammation plays a significant role in the development of atherosclerosis and ASCVD,8-10 and even the formation of plaque.11 4 In the U.S. N Engl J Med.

Cardiovascular Disease 111

Cardiovascular Disease Heart attacks Heart Attack Coronary Artery Disease 111

Journal of the American Heart Association

NOVEMBER 23, 2023

The expression of GPBAR1 in the human endothelium correlated with the expression of inflammatory biomarkers. Mice lackingFxrandGpbar1−/−/Fxr−/−display hypotension and aortic inflammation, along with altered intestinal permeability that deteriorates with age, and severe dysbiosis, along with dysregulated bile acid synthesis.

Aortic 40

Aortic Aneurysm Plaque Cholesterol 40

Physiologically Speaking

MAY 17, 2024

Most of the evidence on the harms of extreme exercise is related to a biomarker of cardiovascular disease known as coronary artery calcification or CAC. Numerous reports in the last decade have found that lifetime endurance athletes have higher levels of coronary artery calcification and plaque compared to age-matched non-athletes.

Physiology 98

Physiology Exercise Biomarkers Cardiovascular Disease 98

Circulation: Cardiovascular Imaging

FEBRUARY 19, 2024

18F-flourodeoxyglucose resting amygdalar uptake, an imaging biomarker of stress-related neural activity, coronary inflammation (fat attenuation index), and high-risk plaque characteristics were assessed by coronary computed tomography angiography. P=0.004), while men had a higher frequency of high-risk plaques (53.7%

Atherosclerosis 40

Atherosclerosis Plaque Coronary Artery Disease Biomarkers 40

Physiologically Speaking

DECEMBER 17, 2024

Cross-sectional studies reveal that endurance athletes, particularly middle-aged and older men, often exhibit higher coronary artery calcium scores (CACS) and plaque prevalence compared to less-active individuals. Notably, athletes engaging in very vigorous-intensity exercise are more likely to develop calcified plaques.

Risk Factors 105

Risk Factors Genetic predisposition Plaque Exercise 105

Frontiers in Cardiovascular Medicine

NOVEMBER 25, 2024

Utilizing single-cell sequencing, highly variable atherosclerotic monocyte subpopulations were systematically identified.

Atherosclerosis 59

Atherosclerosis Biomarkers Plaque Hypertension 59

Cardiometabolic Health Congress

NOVEMBER 14, 2024

He emphasized the evolving landscape of biomarker utility in enhancing the accuracy of HF prediction and the need for targeted interventions based on these biomarkers. He emphasized the evolving landscape of biomarker utility in enhancing the accuracy of HF prediction and the need for targeted interventions based on these biomarkers.

CME 103

CME Obesity Heart Failure Biomarkers 103

Frontiers in Cardiovascular Medicine

NOVEMBER 1, 2024

Further external validation of single gene differential analysis and nomogram identified SGCE, PCDH7, RAB23, and RIMKLB as hub genes; SGCE and PCDH7 were also used as biomarkers to characterize CAS plaque stability.

Atherosclerosis 52

Atherosclerosis Cardiovascular Disease Plaque Biomarkers 52

Dr. S. Venkatesan MD

JANUARY 22, 2025

In these patients there is no plaque triggered ACS. How can biomarkers help us grade these ACSs? One big chunk of ACS-UA is secondary UA where there is increased demand as in stable angina with tachycardia*. For example, in a febrile patient who has associated HT, anemia, etc., It is next to foolishness to rush them to cath lab.

Coronary Angiogram 52

Coronary Angiogram Chest Pain Anatomy Angina 52