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Lowering Atherosclerotic Cardiovascular Disease Events by Treating Residual Inflammatory Risk

DAIC

14,15 Similarly, the NLRP3 inflammasome has been implicated in pathogenesis as it leads to the activation of proinflammatory cytokines triggering robust proinflammatory signaling through interleukin-6 (IL-6) and inducing production of C-reactive protein (CRP), a biomarker for inflammation.16 22 In general, hsCRP values above 2.0 Eur Heart J.