Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP341-ATP341, February 1, 2025. Introduction:Peripheral blood-based biomarker development for neurological diseases such as ischemic stroke has traditionally focused on measuring alterations in leukocyte number and composition. This difference was more pronounced among females.

Biomarkers 40

Biomarkers Strokes Stroke Outcomes 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATMP25-ATMP25, February 1, 2024. Background:Acute brain injuries, including aneurysmal subarachnoid hemorrhage (aSAH), ischemic stroke (IS), and traumatic brain injury (TBI), entail complex recovery processes involving brain plasticity and synaptic regeneration mechanisms.

Biomarkers 40

Biomarkers Outcomes Aneurysm Hemorrhage 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP359-AWP359, February 1, 2025. Background:Mechanical thrombectomy has been associated with improved outcomes in patients with acute ischemic stroke. However, not all patients with successful reperfusion experience good functional outcomes. vs. others, 216.5156.3,

Biomarkers 40

Biomarkers Strokes Stroke Ischemia 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP245-ATP245, February 1, 2024. Background:Ischemic stroke can arise from various etiologies, such as cardioembolism, atherosclerosis, small vessel disease or cryptogenic. Accurate identification of stroke etiology is vital for secondary stroke prevention. had hyperlipidemia.

Biomarkers 40

Biomarkers Strokes Stroke Atherosclerosis 40

Stroke Journal

DECEMBER 14, 2023

Stroke, Ahead of Print. BACKGROUND:Iron status has been associated with functional outcomes after ischemic stroke (IS). This data set included 4 iron status biomarkers, namely, ferritin, total iron binding capacity, iron, and transferrin saturation (TSAT). Nonetheless, this association may be affected by confounders.

Outcomes 40

Outcomes Strokes Stroke Biomarkers 40

Stroke Journal

JANUARY 30, 2025

Stroke, Ahead of Print. Background:Endovascular thrombectomy (EVT) dramatically improves clinical outcomes, but the final infarct volume (FIV) on MRI only accounts for a minority of the treatment effect. Good outcome was defined as 2 on the 90-day modified Rankin Scale. per 1mL; 95%CI: 0.98-1.00; per 1%; 95%CI: 0.94-0.97;

Biomarkers 40

Biomarkers Outcomes Circulation Strokes 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page A74-A74, February 1, 2025. Introduction:Endovascular thrombectomy (EVT) dramatically improves clinical outcomes, but the reduction in final infarct volume only accounts for a minority of the treatment effect. Good functional outcome was defined as a 90-day modified Rankin Scale score 2.

Biomarkers 40

Biomarkers Outcomes Strokes Stroke 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATMP58-ATMP58, February 1, 2024. Objectives:To determine the relationship between patient-reported outcome measures (PROMs) and volumetric biomarkers assessed on clinical imaging in acute ischemic stroke (AIS).Background:AIS Background:AIS is a leading cause of long-term disability.

Strokes 40

Strokes Stroke Outcomes Biomarkers 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP6-AWP6, February 1, 2025. Background and Purpose:Whether imaging markers of cerebral small vessel disease on computed tomography (CT-CSVD) relates to early clinical outcomes after intravenous thrombolysis for acute ischemic stroke remains not well understood. 1.95, p = 0.019).Conclusion:This

Thrombolysis 40

Thrombolysis Outcomes Biomarkers Strokes 40

Stroke Journal

JANUARY 18, 2024

Stroke, Ahead of Print. Accumulating evidence supports a link between sleep disorders, disturbed sleep, and adverse brain health, ranging from stroke to subclinical cerebrovascular disease to cognitive outcomes, including the development of Alzheimer disease and Alzheimer disease–related dementias.

Dementia 90

Dementia Cerebrovascular Disease Biomarkers Strokes 90

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP227-AWP227, February 1, 2025. Introduction:Intracerebral hemorrhage (ICH) is commonly associated with poor neurologic outcomes. Early intervention has been shown to improve patient prognosis, highlighting the necessity of sensitive biomarkers. Specifically, functional parameters (i.e.,

Biomarkers 40

Biomarkers Physiology Hemorrhage Strokes 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATMP112-ATMP112, February 1, 2025. Introduction:Both histological and transcriptomic analyses of acute ischemic stroke (AIS) clots have identified features associated with mechanical thrombectomy (MT) outcome. Expression of DEGs was able to separate clots by FP outcome.

Outcomes 40

Outcomes Strokes Stroke Biomarkers 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

Stroke: Vascular and Interventional Neurology, Volume 3, Issue S2 , November 1, 2023. This secondary study aims to describe the association between the N20 response and imaging biomarkers of ischemic penumbra, infarct volume and collateral flow.MethodsPresence and amplitude of the N20 response was recorded before EVT.

Biomarkers 40

Biomarkers Strokes Stroke Outcomes 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP35-AWP35, February 1, 2025. Neutrophils are reported to be critical mediators of to poor outcome after subarachnoid hemorrhage (SAH). Finally, as neutrophil counts (and the ratio of neutrophils to lymphocytes) are reported to be a biomarker for DCI, we assessed these measures too.

Aneurysm 40

Aneurysm Biomarkers Ischemia Hemorrhage 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ADP16-ADP16, February 1, 2025. Introduction:The National Institutes of Health Stroke Scale (NIHSS) provides a clinical measure of stroke severity. Our outcome was differentially expressed levels of proteins in AIS patients classified by NIHSS scores.

Strokes 40

Strokes Stroke Biomarkers Hospital 40

DAIC

JUNE 4, 2024

I am excited about the potential of the FAI-Score biomarker, which has promising prognostic value beyond existing CT-based methods such as plaque, calcium scoring, and CAD-RADS based interpretation." Details of the study, included in a written statement issued by Caristo Diagnostics, follow. fold higher risk for cardiac mortality and 5.5-fold

Technology 116

Technology Heart attacks Heart Attack Coronary Artery Disease 116

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP320-ATP320, February 1, 2025. The alterations in this pathway have been confirmed in psychiatric disorders, but their role in stroke remains unclear. The alterations in this pathway have been confirmed in psychiatric disorders, but their role in stroke remains unclear. <0.1).

Strokes 40

Strokes Stroke Biomarkers Hemorrhage 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWMP79-AWMP79, February 1, 2025. Background and Purpose:The inflammatory response after ischemic and hemorrhagic stroke is associated with worse clinical outcomes through immune mediated production of pro- inflammatory cytokines.

Exercise 40

Exercise Hemorrhage Strokes Stroke 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

Stroke: Vascular and Interventional Neurology, Volume 3, Issue S2 , November 1, 2023. IntroductionThe Appalachia region of North America is known to have significant health disparities, specifically, worse risk factors and outcomes for stroke.

Health Disparities 40

Health Disparities Outcomes Biomarkers Strokes 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP232-AWP232, February 1, 2025. Accurate prediction of the clinical outcomes in ICH patients is essential for effective clinical management. Results:We included 29 studies comprising 4,597 patients, with a mortality and poor functional outcomes rates of 21.2% and 47.8%, respectively.

Hemorrhage 40

Hemorrhage Outcomes Biomarkers Strokes 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP343-ATP343, February 1, 2025. Background:Subarachnoid Hemorrhage (SAH) accounts for 2-7% of strokes and has high mortality and morbidity. The identified genes and networks may guide the search for potential biomarkers of outcome and novel treatment targets.

Hemorrhage 40

Hemorrhage Outcomes Biomarkers Strokes 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP385-ATP385, February 1, 2025. Emerging research suggests that Vitamin D3 might help protect against brain damage caused by ischemic stroke, as a deficiency in Vitamin D3 can worsen the severity and outcomes of a stroke.

Diet 40

Diet Strokes Stroke Biomarkers 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWP266-AWP266, February 1, 2024. Background:This population-based study investigated the potential of machine learning algorithms to predict stroke incidence and identify important risk factors. These clusters were categorized into high-, medium-, and low-risk groups.

Strokes 40

Strokes Stroke Blood Pressure Laboratory 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP24-ATP24, February 1, 2024. Background:Post-stroke depression (PSD) is a common neuropsychiatric complication of stroke associated with poor functional outcome and increased mortality. Results:A total of 12 studies with 3,230 Patients were included in this analysis.

Strokes 40

Strokes Stroke Biomarkers Diabetes 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATMP119-ATMP119, February 1, 2024. At 7-8 weeks after diabetes onset, control and diabetic rats were treated with ISMN/CZL for 4 weeks, then injected with cholesterol crystal ME and behavioral outcomes were monitored longitudinally for 16 weeks. Some of the biomarkers were unchanged (Table).

Biomarkers 40

Biomarkers Diabetes Cholesterol Strokes 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP272-AWP272, February 1, 2025. However, there are no existing data supporting an independent relationship between cancer and atrial cardiopathy, another atrial pathology associated with increased acute ischemic stroke (AIS) risk.

Cancer 40

Cancer Strokes Stroke Atrial Fibrillation 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWP150-AWP150, February 1, 2024. Dual antiplatelet therapy (DAPT) with aspirin and clopidogrel is standard of care for secondary prevention in non-cardioembolic minor acute ischemic stroke (AIS) and high-risk transient ischemic attack (TIA). 95% CI +30.71 to +176.1;

Strokes 40

Strokes Stroke Biomarkers Outcomes 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWMP81-AWMP81, February 1, 2024. Malnutrition is common in stroke patients and leads to worse outcomes. Body mass index (BMI) is a widely available marker of nutrition status, however studies on BMI and post-ICH outcomes are limited and have conflicting results. 5.94) groups.

Hemorrhage 40

Hemorrhage BMI Outcomes Coronary Artery Disease 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWMP105-AWMP105, February 1, 2025. Introduction:Accurate prediction of the risk of ischemic stroke (IS) is vital for prevention and would be aided by multimodal biomarkers integrating genetic, clinical, and functional data.

Strokes 40

Strokes Stroke Atrial Fibrillation Biomarkers 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP127-ATP127, February 1, 2024. Background/Purpose:Distal medium vessel occlusions (DMVOs) account for a large percentage of vessel occlusions resulting in acute ischemic stroke (AIS) with disabling symptoms. is also associated with good clinical outcomes. Conclusion:A CBV index ≥ 0.7

Outcomes 40

Outcomes Thrombolysis Biomarkers Strokes 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWMP42-AWMP42, February 1, 2025. Background:The Medical Research Council (MRC) scale is used to assess the impact of stroke on muscle strength. Shoulder abduction and finger extension, collectively (SAFE), have been suggested to have prognostic value for stroke outcomes (e.g.

Research 40

Research Strokes Stroke Biomarkers 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page A131-A131, February 1, 2024. The primary outcome was incident ischemic stroke. There were a total of 18 ischemic stroke events among those with LVI (6%) and 65 among those without LVI (3%). Further studies are needed to validate these CMR biomarkers of stroke risk.

Atherosclerosis 40

Atherosclerosis Strokes Stroke Atrial Fibrillation 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWMP8-AWMP8, February 1, 2024. Introduction:Thrombolysis in acute ischemic stroke (AIS) using Tenecteplase (TNK) is gaining popularity compared to Alteplase (ALT) for its practical advantages. At our center, we observed an improvement in clinical outcome in TNK treated patients compared to ALT.

Strokes 40

Strokes Stroke Thrombolysis Biomarkers 40

Frontiers in Cardiovascular Medicine

DECEMBER 9, 2024

BackgroundTrimethylamine N-oxide (TMAO) has been widely explored and considered as a biomarker for adverse cardiovascular events. Associations between TMAO levels, major adverse cardiovascular events (MACE), all-cause mortality, recurrent MI, stroke, etc., No significant association was found in stroke, SYNTAX, and multivessel disease.

Myocardial Infarction 52

Myocardial Infarction Biomarkers Heart Failure Strokes 52

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page A54-A54, February 1, 2024. Introduction:Studies show that successful reperfusion after large-vessel occlusion (LVO) stroke can lead to reduced mass effect and midline shift (MLS). 008, respectively, Figure 1B).Conclusions:Successful

Biomarkers 40

Biomarkers Thrombolysis Strokes Stroke 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

Stroke: Vascular and Interventional Neurology, Volume 3, Issue S2 , November 1, 2023. IntroductionLoss of autoregulation after endovascular therapy (EVT) for large‐artery acute ischemic stroke (AIS) is well documented. [1] Further studies are required to clarify the utility of this biomarker in guiding post‐EVT care.

Strokes 40

Strokes Stroke Blood Pressure Document 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ADP54-ADP54, February 1, 2025. Background:Randomized trials and observational of patients with cervical artery dissection showed no significant difference in ischemic stroke risk with anticoagulation versus antiplatelet therapy. The outcome was ischemic stroke during follow up.

Strokes 40

Strokes Stroke Biomarkers Outcomes 40