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Have We Turned The Tide On Obesity?

Dr. Paddy Barrett

Obesity is one of the world’s biggest health crisis and only seems to be getting worse. For over 50 years, the rates of obesity have continued to rise worldwide 1. The most recent data on obesity has shown a decline for the first time in a very long time. Between 2020 and 2023, the rates of obesity dropped by about 2% 2.

Obesity 81
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Novel Triple-Hormone Agonist Boosts Beta-Cell Function in T2D

Med Page Today

(MedPage Today) -- ORLANDO -- An investigational triple-hormone receptor agonist improved metabolic profiles of people with obesity with or without type 2 diabetes, an exploratory biomarker analysis of a phase II trial found. After 36 weeks.

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Can Lp(a) become the next A1C? A case for digital health management tools to overcome inertia to Lipoprotein (a) testing

Frontiers in Cardiovascular Medicine

Furthermore, we highlight how recent trends in prescription of GLP-1 receptor antagonists are serving to motivate patients to manage biomarkers related to T2D and obesity, which are also relevant in cardiovascular disease.

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The Data For Weight Loss Medications Just Keeps Pouring In.

Dr. Paddy Barrett

For over 50 years, rates of those who are overweight or obese have been rising rapidly. Despite the rise in obesity rates, the growing recognition of it as a global problem and the astronomical sums of money we spend on addressing it, the tide continues to rise. That is until now. The answer is… eye wateringly well.

Obesity 79
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Obesity-Related Biomarkers Are Associated With Exercise Intolerance and HFpEF

Circulation: Heart Failure

Fasting blood samples collected at the time of the cardiopulmonary exercise test were used to assay obesity-related biomarkers. Our findings suggest that among the obesity-related biomarkers studied, higher levels of leptin and CRP are independently associated with increased odds of HFpEF, with odds ratios of 1.36 (95% CI, 1.09–1.70)

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Anti-obesity drugs, lifestyle interventions show cardiovascular benefits beyond weight loss

Medical Xpress - Cardiology

Popular anti-obesity drugs continue to show cardiovascular benefits beyond weight loss, according to several new papers published in JACC that are being simultaneously presented at the American Heart Association's 2024 Scientific Sessions.

Obesity 40
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Unhealthy visceral fat is associated with improved efficacy of immunotherapy in endometrial cancer

Journal of Clinical Investigation - Cardiology

Obesity is a known driver of endometrial cancer. Notably, a BMI in the overweight or obese range was paradoxically associated with improved progression-free and overall survival.

Cancer 63