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Safety and possible anti-inflammatory effect of paclitaxel associated with LDL-like nanoparticles (LDE) in patients with chronic coronary artery disease: a double-blind, placebo-controlled pilot study

Frontiers in Cardiovascular Medicine

We investigated whether treatment with LDE-paclitaxel changes plaque progression by coronary CT angiography and is safe in patients with chronic coronary artery disease. Clinical and laboratory safety evaluations were made at baseline and every 3 weeks until the end of the study.

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Coronary Artery Calcification: Current Concepts and Clinical Implications

Circulation

Nevertheless, the relationship between CAC and the susceptibility of a plaque to provoke a thrombotic event remains incompletely understood. This review summarizes the current understanding and literature on CAC.

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Micro and Nanoplastics and Cardiovascular Events – Recent Study

All About Cardiovascular System and Disorders

Detailed analysis of the excised carotid plaques were carried out with pyrolysis-gas chromatography-mass spectrometry, stable isotope analysis, and electron microscopy. Inflammatory biomarkers were also estimated. Comparison was with those who had no evidence of these plastics in the plaques.

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