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Tenax Therapeutics Announces New U.S. Patent Covering the Use of Levosimendan in Pulmonary Hypertension with Heart Failure with Preserved Ejection Fraction (PH-HFpEF)

DAIC

Initially discovered and developed by Orion Corporation in Finland, intravenous levosimendan is approved in 60 countries outside the United States for use in hospitalized patients with acutely decompensated heart failure. Getty Images milla1cf Mon, 05/06/2024 - 10:48 May 6, 2024 — Tenax Therapeutics, Inc. ,

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Evidence-Based Application of Natriuretic Peptides in the Evaluation of Chronic Heart Failure With Preserved Ejection Fraction in the Ambulatory Outpatient Setting

Circulation

In our study, NT-proBNP provided little value in those with AF and dyspnea because the presence of AF is by itself a robust biomarker of HFpEF. Circulation, Ahead of Print.

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Rationale and design of the ESC Heart Failure III Registry – Implementation and discovery

European Journal of Heart Failure

Methods Between 1 November 2018 and 31 December 2020, 10 162 patients with chronic or acute/worsening HF with reduced, mildly reduced, or preserved ejection fraction were enrolled from 220 centres in 41 European or ESC affiliated countries.

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Metabolic dysfunction and incidence of heart failure subtypes among Black individuals: The Jackson Heart Study

European Journal of Heart Failure

We assessed the associations of MetS indices with echocardiographic parameters, biomarkers of myocardial damage (high-sensitivity cardiac troponin I [hs-cTnI] and B-type natriuretic peptide [BNP]) and incident HF hospitalizations including HF with preserved ejection fraction (HFpEF) and HF with reduced ejection fraction (HFrEF).

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Carbohydrate antigen 125 concentrations across the ejection fraction spectrum in chronic heart failure: The EMPEROR programme

European Journal of Heart Failure

CI, confidence interval; CV, cardiovascular; HF, heart failure; HFpEF, heart failure with preserved ejection fraction; HFrEF, heart failure with reduced ejection fraction; HHF, hospitalization for heart failure. The primary outcome was a composite of first HF hospitalization or cardiovascular (CV) death.

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Hepatocyte growth factor and B-type natriuretic peptide as independent predictors of mortality in HFpEF patients

Frontiers in Cardiovascular Medicine

BackgroundHeart failure with preserved ejection fraction (HFpEF) is a common and heterogeneous syndrome with high mortality and morbidity. The patients were divided into two groups according to the 24-month follow-up results: deceased (82 cases) and survivors (330 cases).

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Catheter ablation of atrial fibrillation in women with heart failure with preserved ejection fraction

Frontiers in Cardiovascular Medicine

BackgroundHeart failure with preserved ejection fraction (HFpEF) and atrial fibrillation (AF) often coincide. During follow-up, HFpEF-patients more often experienced AF-related re-hospitalization (36.8% Forty-two were female. ml/m2 vs. 25.8 ml/m2, g/m2 vs. 83.0 g/m2, vs. 31.1%, P = 0.109).