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Hereditary Transthyretin Cardiac Amyloidosis With the p.V142I Variant: Mechanistic Insights and Diagnostic Challenges

Circulation: Heart Failure

About 3% to 4% of patients with African ancestry carry this genetic predisposition to develop signs and symptoms of hATTR-CA. Nevertheless, clinical manifestations of hATTR-CA appear only late in the fifth and sixth decades of life, despite its clear genetic background.

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How To Reduce The Risk Of Heart Disease If You Have Insulin Resistance.

Dr. Paddy Barrett

Yes, there is a genetic predisposition at play. 1 Association of lipid, inflammatory, and metabolic biomarkers with age at onset for incident coronary heart disease in women. But why wait? We know that getting most of these same factors in line early in life can mean avoiding type 2 diabetes entirely 4. For sure. (

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Lifestyle Risk Factors Predict Coronary Calcification among Male Endurance Athletes

Physiologically Speaking

Therefore, athletes, especially those with genetic predispositions or cardiovascular symptoms, should monitor their health history, risk factors, and exercise intensity carefully to balance performance and long-term heart health. The study included 289 male athletes with a mean age of 60 years.