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Non-ischemic phenotypes of low-risk chest pain patients based on exercise stress echocardiography: a pilot study

Frontiers in Cardiovascular Medicine

We aimed to identify non-ischemic phenotypes in low-risk NSTE-ACS patients by analyzing a wide range of parameters available during exercise SE.MethodsInpatients [n=103, median age 56 (4665)years, 65 (63%) men] with suspected NSTE-ACS without high-risk criteria underwent exercise SE using a semi-supine cycle ergometer.

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Physiology Friday #200: Higher Aerobic Fitness is Tied to Slower Biological Aging

Physiologically Speaking

One of the most promising biomarkers of biological age are so-called DNA methylation-based age estimators, otherwise known as DNA methylation age clocks. Physical fitness was measured using VO2 peak obtained during a maximal exercise test (the gold standard way to measure this outcome). What can’t we infer from this study?

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Is VO2 Max the Best Measure of Fitness and Performance?

Physiologically Speaking

Within exercise and sports science, no one measure has gotten more attention than VO2 max. VO2 max refers to your maximum rate of oxygen consumption, and it’s typically measured during a maximal exercise test to exhaustion (they’re not fun, trust me). Outside of a research context, this also applies to you.

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New Drug Fails to Improve Diabetes-Related Heart Failure

DAIC

The research was presented at the American College of Cardiology ’s Annual Scientific Session. Decline in exercise ability is a hallmark of progression to overt heart failure. The researchers also conducted a preplanned subgroup analysis comparing outcomes for patients who were or were not on SGLT2 inhibitors or GLP-1 RAs at baseline.

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Bayer to Present New Investigational Heart Failure Data, Continued Portfolio Research in Chronic Kidney Disease at ACC.25

DAIC

25 include Efficacy and safety of finerenone across the spectrum of kidney risk in heart failure with mildly reduced or preserved ejection fraction during the session;"Innovations and Insights in Heart Failure With Preserved Ejection Fraction: Emerging Therapies, Biomarkers and Mechanistic Studies." Additional ACC.25

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Physiology Friday #211: Morning vs. Evening Exercise for Blood Pressure and Autonomic Nervous System Health

Physiologically Speaking

There’s a surge in research devoted to finding the best time to exercise. In a new study, evening exercise, but not morning exercise, reduced blood pressure, lowered sympathetic activity, and improved baroreflex sensitivity in a group of adults with treated hypertension. “When is the best time to exercise?

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Bayer to Present New Investigational Heart Failure Data, Continued Portfolio Research

DAIC

25 include Efficacy and safety of finerenone across the spectrum of kidney risk in heart failure with mildly reduced or preserved ejection fraction during the session;"Innovations and Insights in Heart Failure With Preserved Ejection Fraction: Emerging Therapies, Biomarkers and Mechanistic Studies." Additional ACC.25