Physiologically Speaking

MARCH 13, 2024

Within exercise and sports science, no one measure has gotten more attention than VO2 max. VO2 max refers to your maximum rate of oxygen consumption, and it’s typically measured during a maximal exercise test to exhaustion (they’re not fun, trust me). The VO2 plateau indicating the achievement of VO2 max.

Exercise 52

Exercise Physiology Research Biomarkers 52

Physiologically Speaking

AUGUST 9, 2024

So rather than investigate how specific nutrients affect health biomarkers, there’s a growing interest in how restricting or supplying these nutrients might affect physical activity and energy expenditure, key factors in overall health. It’s also important to acknowledge that each of us respond to nutrients and food differently.

Physiology 69

Physiology Diet Cholesterol Biomarkers 69

DAIC

APRIL 9, 2024

Decline in exercise ability is a hallmark of progression to overt heart failure. The international ARISE-HF trial was designed to test the effectiveness of the investigational drug AT-001 at stabilizing exercise capacity in patients with diabetic cardiomyopathy. Patients had had Type 2 diabetes for an average of 14 years.

Heart Failure 52

Heart Failure Diabetes Cardiomyopathy Exercise 52

DAIC

MARCH 25, 2025

Ten presentations will feature new data from the pivotal Phase III FINEARTS-HF cardiovascular (CV) outcomes trial, which investigated KERENDIA for treatingt adult patients with heart failure (HF) with a left ventricular ejection fraction (LVEF) of 40%, i.e., mildly reduced LVEF (HFmrEF) or preserved LVEF (HFpEF). Additional ACC.25

Preserved Ejection Fraction 52

Preserved Ejection Fraction Heart Failure Kidney Disease Research 52

Physiologically Speaking

MARCH 29, 2024

There’s a surge in research devoted to finding the best time to exercise. In a new study, evening exercise, but not morning exercise, reduced blood pressure, lowered sympathetic activity, and improved baroreflex sensitivity in a group of adults with treated hypertension. “When is the best time to exercise? .

Blood Pressure 52

Blood Pressure Exercise Physiology Hypertension 52

DAIC

MARCH 25, 2025

Ten presentations will feature new data from the pivotal Phase III FINEARTS-HF cardiovascular (CV) outcomes trial, which investigated KERENDIA for treatingt adult patients with heart failure (HF) with a left ventricular ejection fraction (LVEF) of 40%, i.e., mildly reduced LVEF (HFmrEF) or preserved LVEF (HFpEF). Additional ACC.25

Preserved Ejection Fraction 52

Preserved Ejection Fraction Heart Failure Research Academic 52

Cardiometabolic Health Congress

AUGUST 8, 2024

This blog post explores the development of such partnerships and their potential to transform healthcare outcomes. Engaging individuals as active participants in their care plans can significantly enhance outcomes and improve overall quality of life.

Education 59

Education Cardiovascular Disease Diabetes Kidney Disease 59

Dr. Paddy Barrett

APRIL 12, 2024

But for many people regular exercise at even moderate intensities will not be on the cards. Maybe you are one of the fortunate ones who loves to exercise at a high level and has managed to land in the top 2.5% Even 30 minutes per day has been shown to improve health outcomes 6. That is something we can all aim for. But walking.

Quality of Life 125

Quality of Life Blood Pressure Exercise Chronic Disease 125

DAIC

OCTOBER 2, 2024

vs 24% showed enhanced exercise capacity and 84% vs 8% demonstrated a substantial response in cardiac biomarkers (for all p aficamten achieved one or more clinically relevant outcomes, 62% achieved at least three outcomes and 23% achieved all four outcomes.

Cardiomyopathy 40

Cardiomyopathy Sudden Cardiac Death Biomarkers Heart Failure 40

Physiologically Speaking

DECEMBER 8, 2023

Exercise is the most potent longevity intervention we have at our disposal. To my knowledge, there’s not a study that doesn’t show that at least some exercise is better than none , and most even show that more exercise is better when it comes to improving healthspan and lifespan. Not completely.

Exercise 59

Exercise Physiology Research Biomarkers 59

Open Heart

AUGUST 16, 2023

Objective To characterise cardiac remodelling, exercise capacity and fibroinflammatory biomarkers in patients with aortic stenosis (AS) with and without diabetes, and assess the impact of diabetes on outcomes. Secondary endpoint was all-cause death. to 4.00; p=0.037).

Exercise 52

Exercise Diabetes Stenosis Aortic 52

Heart BMJ

NOVEMBER 25, 2024

Background Participation in regular exercise activities is recommended for patients with chronic heart failure. However, less is known about the effect of exercise in patients with genetic dilated cardiomyopathy (DCM). Trial design Non-randomised clinical pre-post trial of exercise training. mL/kg / min (95% CI +0.9 p=0.002).

Exercise 52

Exercise Cardiomyopathy Outpatient Biomarkers 52

Physiologically Speaking

DECEMBER 17, 2024

This has raised concerns that long-term, high-volume exercise might be detrimental to heart health. Notably, athletes engaging in very vigorous-intensity exercise are more likely to develop calcified plaques. Training load : Weekly exercise volume, measured as MET-hours/week, showed a positive trend.

Risk Factors 105

Risk Factors Genetic predisposition Plaque Exercise 105