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Obesity-Related Biomarkers Are Associated With Exercise Intolerance and HFpEF

Circulation: Heart Failure

We defined HFpEF based on the presence of elevated left ventricular filling pressures at rest or during exercise. Fasting blood samples collected at the time of the cardiopulmonary exercise test were used to assay obesity-related biomarkers. mL/kg per min lower peak VO2(β, −2.35±0.19;P<0.001). P<0.001). for all).

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Non-ischemic phenotypes of low-risk chest pain patients based on exercise stress echocardiography: a pilot study

Frontiers in Cardiovascular Medicine

We aimed to identify non-ischemic phenotypes in low-risk NSTE-ACS patients by analyzing a wide range of parameters available during exercise SE.MethodsInpatients [n=103, median age 56 (4665)years, 65 (63%) men] with suspected NSTE-ACS without high-risk criteria underwent exercise SE using a semi-supine cycle ergometer.

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Hemodynamics of Exercise-Induced Hypertension and Relationship to Outcomes in Adults With Coarctation of the Aorta

Circulation: Heart Failure

EIH was defined as systolic blood pressure (BP) at peak exercise >210 mm Hg in men or >190 mm Hg in women.RESULTS:In this prospective cohort study, we assessed patients with COA (n=41, age 4314 years, 26 [63%] men) and healthy controls (n=41).

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Roche's Lp(a) Gen.2 Molarity Assay Receives FDA Clearance

DAIC

This clearance comes in advance of disease-modifying therapies on the horizon expected to help clinicians use this biomarker to guide patients to improved cardiovascular health, saidBrad Moore, president and CEO at Roche Diagnostics North America. The development of the Tina-quant Lipoprotein (a) Gen.2

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Tenax Therapeutics Announces New U.S. Patent Covering the Use of Levosimendan in Pulmonary Hypertension with Heart Failure with Preserved Ejection Fraction (PH-HFpEF)

DAIC

Patients who transitioned to the oral daily formulation after a lengthy treatment with the weekly IV formulation improved further in this assessment of exercise tolerance, which is the primary endpoint of the ongoing Phase 3 LEVEL study. Getty Images milla1cf Mon, 05/06/2024 - 10:48 May 6, 2024 — Tenax Therapeutics, Inc. ,

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Investigators identify novel plasma proteins linked to future risk of hypertension

Medical Xpress - Cardiology

Exercise testing can serve as a powerful physiologic probe to unmask subclinical cardiovascular abnormalities well before disease onset. For example, blood pressure changes during exercise (EBP) can reveal a latent tendency toward future development of hypertension.

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Role of physical activity in cardiovascular disease prevention: impact of epigenetic modifications

Frontiers in Cardiovascular Medicine

Indeed, moderate exercise is not only beneficial to the heart in healthy populations, but also exerts a protective effect in pathological states. However, the molecular mechanisms underlying the cardioprotective effects of exercise are still not fully understood.