Remove Biomarkers Remove Dementia Remove Research
article thumbnail

Do Statins Cause Dementia?

Dr. Paddy Barrett

I am going to start with the answer to the question of whether statins cause dementia and then provide the details backing up my answer. Statins do not cause dementia. But if you are someone who thinks that statins do cause dementia and you need to see the evidence to refute that claim, then read on. The answer is: No.

article thumbnail

Soluble Biomarkers of Cerebrovascular Pathologies

Stroke Journal

Vascular contributions to cognitive impairment and dementia (VCID) is an all-encompassing term that describes cognitive impairment due to cerebrovascular origins. With the advancement of imaging and pathological studies, we now understand that VCID is often comorbid with Alzheimer disease.

article thumbnail

Cardiac noradrenergic deficiency revealed by 18F-dopamine positron emission tomography identifies preclinical central Lewy body diseases

Journal of Clinical Investigation - Cardiology

In Lewy body diseases (LBDs) Parkinson disease (PD), and dementia with Lewy bodies (DLB), by the time parkinsonism or cognitive dysfunction manifests clinically, substantial neurodegeneration has already occurred. Division of Intramural Research, NIH, NINDS. BACKGROUND. TRIAL REGISTRATION. ClinicalTrials.gov NCT00775853.

article thumbnail

Have We Turned The Tide On Obesity?

Dr. Paddy Barrett

I have covered this topic previously here , but it is clear that inflammation plays a major role in the initiation and progression of coronary artery disease, and the inflammatory biomarker hsCRP is tightly connected to this process. Dementia is a leading cause of death and a major concern for most people as they age. N Engl J Med.

Obesity 84
article thumbnail

The Data For Weight Loss Medications Just Keeps Pouring In.

Dr. Paddy Barrett

Recent research suggested that the weight loss market was estimated to be worth $224 billion annually in 2021 and is estimated to exceed $400 billion by 2024 1. Type 2 Diabetes When it comes to the increasing the risk of major chronic diseases such as cardiovascular disease, many cancers and dementia, type 2 diabetes plays a huge role.

Obesity 81
article thumbnail

Abstract WP45: MRI-Visible Perivascular Spaces and Cognitive Performance: A Cross-Sectional Analysis from The Framingham Heart Study

Stroke Journal

They are key indicators of cerebral small vessel disease (CSVD) and are associated with mild cognitive impairment (MCI) and dementia. These findings suggest a role for MRI-visible PVS as an early biomarker for the identification of those at risk of MCI or dementia.

article thumbnail

The legal case – naming a few names

Dr. Malcolm Kendrick

As outlined by the Telegraph newspaper in the UK: ‘The British Sugar Bureau put out a press release dismissing Yudkin’s claims as “emotional assertions” and the World Sugar Research Organisation described his book as “science fiction”. He discovered this by using the conspiratorial activity called…research.