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Infection, Inflammation, and Poststroke Cognitive Impairment

Journal of the American Heart Association

BackgroundInfection and inflammation are dementia risk factors in population‐based cohorts; however, studies in stroke are scarce. women; mean education, 12.6 [SD, Journal of the American Heart Association, Ahead of Print. Among 255 patients (mean age, 73.9 [SD,

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Abstract WP49: Diagnostic performance of plasma pTau217 for the detection of Cognitive Impairment in a Vascular Disease-Enriched Population

Stroke Journal

While plasma pTau217 is an established biomarker for AD, its relevance in vascular disease-enriched populations has not been extensively studied. Individuals were classified based on their cognitive status into cognitively normal, mild cognitive impairment (MCI), or dementia.

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Plasma Markers of Alzheimer's Disease Pathology, Neuronal Injury, and Astrocytic Activation and MRI Load of Vascular Pathology and Neurodegeneration: The SMART?MR Study

Journal of the American Heart Association

BackgroundTwo of the main causes for dementia are Alzheimer's disease (AD) and vascular pathology, with most patients showing mixed pathology. Journal of the American Heart Association, Ahead of Print. Logistic regressions were performed for the presence of lacunar and cortical infarcts. 0.26],P=0.015). Higher NfL (b=−5.63, [95% CI, −8.95

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Abstract WP45: MRI-Visible Perivascular Spaces and Cognitive Performance: A Cross-Sectional Analysis from The Framingham Heart Study

Stroke Journal

They are key indicators of cerebral small vessel disease (CSVD) and are associated with mild cognitive impairment (MCI) and dementia. male, 49% college educated, 17.5% These findings suggest a role for MRI-visible PVS as an early biomarker for the identification of those at risk of MCI or dementia. CSO high burden, 9.8%

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Why Muscle Power Is The Key To Healthy Ageing.

Dr. Paddy Barrett

A critical component of healthy ageing is the maintenance of cognitive capacity and avoidance of dementia. Muscle power may also play a role in the prevention or progression of dementia. Higher muscle power measures, such as gait (walking) speed, were associated with a 50% reduction in the risk of dementia 6. Am J Prev Med.

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