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Their findings could lead to new therapies for people with endothelial dysfunction, a type of disorder that contributes to coronaryarterydisease that may occlude with plaque and lack ability to carry sufficient blood into the heart tissue causing a heartattack.
fold higher risk for major adverse cardiac events (MACE) Caristo's AI-Risk model, CaRi-Heart Risk Score, outperformed other scores in routine clinical use for prediction of cardiac mortality, and when presented to clinicians, resulted in changes of management decision in 45% of the patients. "The fold higher risk for cardiac mortality and 5.5-fold
Diabetic cardiomyopathy is a disease in which chronically high levels of blood glucose (hyperglycemia) damage the heart muscle, leading to heart failure over time. Patients had had Type 2 diabetes for an average of 14 years.
A therapy that has been proven repeatedly to reduce the probability of heartattacks and strokes in multiple double-blind randomised controlled studies 1. They are also at an increased risk of coronaryarterydisease (Discussed in more detail here ). This one requires some nuance. My approach for APOE 4 patients.
MILLER, PHD, LED THE DEVELOPMENT OF A NEW "ATHEROSCLEROSIS ATLAS" THAT DETAILS, AT THE LEVEL OF INDIVIDUAL CELLS, CRITICAL PROCESSES RESPONSIBLE FOR FORMING THE HARMFUL PLAQUE BUILDUP THAT CAUSES HEARTATTACKS, STROKES AND CORONARYARTERYDISEASE.
Atherosclerotic cardiovascular disease (ASCVD), caused by plaque buildup in arterial walls, is one of the leading causes of disability and death worldwide.1,2 1,2 ASCVD causes or contributes to conditions that include coronaryarterydisease (CAD), cerebrovascular disease, and peripheral vascular disease (inclusive of aortic aneurysm).3
Diamond and Forrester accomplished this by first establishing the prevalence of coronaryarterydisease based on how clinically likely patients with chest pain symptoms were found to have coronarydisease based on a coronary angiogram. Thanks for reading Dr. Anish Koka's Newsletter! This happens.
In a cohort of >3,000 people from the National Health and Nutrition Examination Survey (NHANES), sleeping <6 hours each night predicted a higher prevalence of stroke, heartattack, and chronic heart failure. 19 20 Mortality from CVD and coronaryheartdisease is also increased in women with short sleep, but not men.
Studies, including the MARC study, show that athletes have a higher proportion of calcified (stable) plaques and fewer mixed or non-calcified plaques, which are more prone to rupture and cause heartattacks. The study included 289 male athletes with a mean age of 60 years.
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