Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP341-ATP341, February 1, 2025. Introduction:Peripheral blood-based biomarker development for neurological diseases such as ischemic stroke has traditionally focused on measuring alterations in leukocyte number and composition. This difference was more pronounced among females.

Biomarkers 40

Biomarkers Stroke Strokes Outcomes 40

Stroke Journal

FEBRUARY 5, 2025

Stroke, Ahead of Print. Growth Differentiation Factor 11 (GDF11), a member of the TGF- superfamily, is a circulating protein involved in cellular development and tissue repair. Background:Stroke remains a leading cause of death and disability, underscoring the urgent need for treatments that enhance recovery.

Ischemia 45

Ischemia Stroke Strokes Biomarkers 45

Cardiovascular Diabetology

JUNE 20, 2024

Circulating atherogenic index of plasma (AIP) levels has been proposed as a novel biomarker for dyslipidemia and as a predictor of insulin resistance (IR) risk. However, the association between AIP and the inc.

Biomarkers 52

Biomarkers Circulation Stroke Strokes 52

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP6-ATP6, February 1, 2024. Background:Brain arteriovenous malformations (bAVMs) are an important cause of intracranial hemorrhage, seizure, or other neurological deficits. Clinical heterogeneity of bAVM suggests a role for genetic modifiers that may associate with seizure risk.

Circulation 40

Circulation Biomarkers Hemorrhage Stroke 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

Stroke: Vascular and Interventional Neurology, Volume 3, Issue S2 , November 1, 2023. IntroductionThe routinely used computed tomography (CT)‐based workup in the setting of acute ischemic stroke (AIS) includes non‐contrast brain CT, CT angiography (CTA), and CT perfusion.

Hemorrhage 40

Hemorrhage Biomarkers Stroke Strokes 40

Stroke Journal

JANUARY 30, 2025

Stroke, Ahead of Print. An imaging biomarker that more strongly correlates with post-EVT functional outcome would be helpful for clinical prognosis and serve as a surrogate outcome measure in trials of EVT-adjuvant therapies.

Biomarkers 40

Biomarkers Outcomes Circulation Stroke 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page A74-A74, February 1, 2025. There is a need for surrogate imaging biomarkers that more strongly associate with functional outcome, to refine prognostication and facilitate development of EVT-adjuvant neuroprotective therapies. MRI was performed 1248 hours post-EVT.

Biomarkers 40

Biomarkers Outcomes Stroke Strokes 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP12-ATP12, February 1, 2024. Piperine reported the lowest SSE (9.77; 438.33) with respective QSM and DCEQP relative changeConclusion:Changes in circulating metabolites accurately reflect changes in lesional iron content and permeability in CASH during yearly follow-up.

Biomarkers 40

Biomarkers Hemorrhage Circulation Stroke 40

DAIC

JANUARY 23, 2024

3 Patients with ASCVD are at a higher risk for major adverse cardiovascular events (MACE) including heart attack or myocardial infarction (MI), stroke, and cardiovascular (CV) death.4 Atherosclerotic cardiovascular disease (ASCVD), caused by plaque buildup in arterial walls, is one of the leading causes of disability and death worldwide.1,2

Cardiovascular Disease 111

Cardiovascular Disease Heart Attack Heart attacks Coronary Artery Disease 111

Stroke Journal

DECEMBER 19, 2024

Stroke, Ahead of Print. Additionally, an association between tortuosity, being a readily measurable biomarker in routine magnetic resonance angiography, and proteomic markers of dissection recurrence exists, further enhancing the prospect of underlying subclinical connective tissue disease in dissection patients.

Biomarkers 75

Biomarkers Risk Factors Circulation Hospital 75

Circulation

NOVEMBER 11, 2024

Circulation, Volume 150, Issue Suppl_1 , Page A4148181-A4148181, November 12, 2024. Background:Following an ischemic stroke, a serious complication known as hemorrhagic transformation (HT) might jeopardize patient outcomes.

Hemorrhage 40

Hemorrhage Stroke Strokes Myocardial Infarction 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP150-ATP150, February 1, 2024. Introduction:Ischemic stroke is a leading cause of death and disability in the US, with 20-40% of cases, classified as cryptogenic or with an unexplained cause. Stroke in multiple vascular territories MVT was present in 22/101 (22%) at baseline.

Atrial Fibrillation 40

Atrial Fibrillation Stroke Strokes Biomarkers 40

Dr. Paddy Barrett

FEBRUARY 21, 2025

That is severe obstructive sleep apnea (OSA), and with that serious interruption to sleep quality also comes a doubling in the risk of future heart disease, particularly stroke 6. Circulation. 10 Association of lipid, inflammatory, and metabolic biomarkers with age at onset for incident coronary heart disease in women.

Obesity 77

Obesity Diabetes Cardiovascular Disease Chronic Disease 77

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP268-ATP268, February 1, 2025. Introduction:Xylitol, a sugar alcohol with a global market estimated at 161,500 metric tons, has been linked to increased thrombosis and risk of stroke and heart attack.

Thrombosis 40

Thrombosis Obesity Stroke Strokes 40

Circulation

OCTOBER 22, 2023

Circulation, Ahead of Print. The key secondary endpoint was the composite of death, myocardial infarction (MI), or stroke. of patients were female and 55% presented with biomarker positive ACS. Rates of all-cause death, MI, or stroke were not significantly different between groups (2.4% years, 23.2% 1.21; P = 0.515).

Myocardial Infarction 40

Myocardial Infarction Biomarkers Academic Stroke 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATMP75-ATMP75, February 1, 2024. Background:Cerebral microbleeds (CMBs) are age-related vascular lesions, predisposing patients to a lifetime risk of hemorrhagic stroke and cognitive decline. The spatial transcriptomics identified 19 DEGs between CMBs and control tissue (p<0.1,

Biomarkers 40

Biomarkers Hemorrhage Stroke Strokes 40

Stroke: Vascular and Interventional Neurology

JUNE 20, 2024

Stroke: Vascular and Interventional Neurology, Ahead of Print. While traditional vascular risk factors (eg, hypertension, dyslipidemia, tobacco use) account for 20% of the explained variance in carotid atherosclerosis, they remain a prominent focus for primary and secondary ischemic stroke prevention strategies.

Cerebrovascular Disease 40

Cerebrovascular Disease Atherosclerosis Atrial Fibrillation Physiology 40

Circulation

NOVEMBER 11, 2024

Circulation, Volume 150, Issue Suppl_1 , Page A4141170-A4141170, November 12, 2024. These findings suggest that 5-HTP could potentially be used as a biomarker for cardiovascular risk stratification. In cardiovascular research, serotonin has been implicated in modulating vascular tone, platelet aggregation, and myocardial function.

Myocardial Infarction 40

Myocardial Infarction Coronary Artery Bypass Graft STEMI Angina 40

Stroke Journal

JANUARY 23, 2024

Stroke, Ahead of Print. BACKGROUND:Moyamoya disease (MMD) is a rare and complex pathological condition characterized by an abnormal collateral circulation network in the basal brain. The diagnosis of MMD and its progression is unpredictable and influenced by many factors.

Biomarkers 40

Biomarkers Circulation Stroke Strokes 40

Dr. Paddy Barrett

SEPTEMBER 19, 2023

A therapy that has been proven repeatedly to reduce the probability of heart attacks and strokes in multiple double-blind randomised controlled studies 1. The cholesterol circulating in your bloodstream represents a very small fraction of your body’s total available cholesterol. Share So What Does The Data Say? J Lipid Res.

Dementia 52

Dementia Cholesterol Biomarkers Coronary Artery Disease 52

DAIC

JANUARY 22, 2024

The International Stroke Conference 2024 will be held Feb. According to program planners with the American Stroke Association, a division of the American Heart Association, findings from late-breaking science will include multiple high profile randomized clinical trials like RESILIENT-Extend, EMBOLISE, STEM, ZODIAC, among many others.

Stroke 100

Stroke Strokes Hospital Stents 100

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWMP99-AWMP99, February 1, 2025. Introduction:Circulating plasma protein profiling in individuals with brain vascular disorders may aid in the identification of robust diagnostic biomarkers, stratification of high-risk patients for treatment, and monitoring of disease progression or treatment response.

Biomarkers 40

Biomarkers Circulation Hemorrhage Stroke 40

Stroke Journal

MARCH 23, 2025

Stroke, Volume 56, Issue 4 , Page 915-925, April 1, 2025. BACKGROUND:Diffusion-weighted magnetic resonance imaging is essential for diagnosing ischemic stroke and identifying targets for emergency revascularization. mL versus 3.78

Stroke 40

Stroke Strokes Biomarkers Circulation 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

Stroke: Vascular and Interventional Neurology, Volume 3, Issue S2 , November 1, 2023. There is a clear need for imaging biomarkers that are strongly associated with long‐term functional outcome after EVT, both in clinical practice and clinical trial design (surrogate outcome measure). Imaging was processed via RAPID software.

Biomarkers 40

Biomarkers Outcomes Stroke Strokes 40

Circulation

NOVEMBER 14, 2024

Circulation, Ahead of Print. BACKGROUND:Many studies have explored whether individual plasma protein biomarkers improve cardiovascular disease risk prediction. CONCLUSIONS:Measurement of targeted protein biomarkers produced superior prediction of aggregated and disaggregated cardiovascular events.

Cardiovascular Disease 40

Cardiovascular Disease Dementia Biomarkers Myocardial Infarction 40

Society of Thoracic Surgeons - Research

APRIL 20, 2023

Part 1: Concepts, Indicator Variables, and Controversies The Annals of Thoracic Surgery January 2022 Arman Kilic Supplementing Existing Societal Risk Models for Surgical Aortic Valve Replacement With Machine Learning for Improved Prediction Journal of the American Heart Association November 2021 Jared Belle Strategies for Mechanical Right Ventricular (..)

Research 52

Research Coronary Artery Bypass Graft Aortic valve Congenital 52

Society of Thoracic Surgeons - Research

APRIL 20, 2023

Institutional Coronary Artery Bypass Case Volumes and Outcomes European Journal of Heart Failure October 2023 Makoto Mori 1 Robotic Mitral Valve Repair for Degenerative Mitral Regurgitation The Annals of Thoracic Surgery August 2023 Carlos Diaz-Castrillion 2 Volume-Failure to Rescue Relationship in Acute Type A Aortic Dissections: An Analysis of The (..)

Research 52

Research Coronary Artery Bypass Graft Aortic valve Congenital 52

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWMP14-AWMP14, February 1, 2025. Introduction:Cerebral microbleeds (CMBs) are age-related manifestations of microangiopathies predisposing patients to hemorrhagic stroke (HS) and cognitive decline. Little work has currently been done to elucidate mechanisms in the pathophysiology of CMBs.

Biomarkers 40

Biomarkers Hemorrhage Stroke Strokes 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWP160-AWP160, February 1, 2024. In this study, we examined the relationship between ICH and CKD, as well as intracranial arterial calcification (IAC) as an intermediate biomarker. The relationship between eGFR and IAC was assessed with Pearson correlation and one-way ANOVA.

Kidney Disease 40

Kidney Disease Hemorrhage Risk Factors Biomarkers 40