Frontiers in Cardiovascular Medicine

APRIL 24, 2024

The early detection of plaques by circulating biomarkers is highly clinically relevant to prevent the occurrence of major complications such as stroke or heart attacks. miRNA expression profiles of serum-derived EVs were obtained by small RNA sequencing and in plaque material simultaneously acquired from patients.

Plaque 52

Plaque Biomarkers Circulation Stenosis 52

DAIC

FEBRUARY 3, 2025

This clearance comes in advance of disease-modifying therapies on the horizon expected to help clinicians use this biomarker to guide patients to improved cardiovascular health, saidBrad Moore, president and CEO at Roche Diagnostics North America. Circulation. The development of the Tina-quant Lipoprotein (a) Gen.2 Arnett DK et al.

Cardiovascular Disease 52

Cardiovascular Disease Aortic valve Biomarkers Innovation 52

Circulation

NOVEMBER 11, 2024

Circulation, Volume 150, Issue Suppl_1 , Page A4146638-A4146638, November 12, 2024. Introduction/Background:According to the American Heart Association, the accumulation of plaque in the walls of arteries is identified as the primary cause of atherosclerotic cardiovascular disease (ASCVD).

Biomarkers 40

Biomarkers Cardiovascular Disease Laboratory Plaque 40

Circulation

JANUARY 15, 2024

Circulation, Volume 149, Issue 3 , Page 251-266, January 16, 2024. Nevertheless, the relationship between CAC and the susceptibility of a plaque to provoke a thrombotic event remains incompletely understood. Coronary artery calcification (CAC) accompanies the development of advanced atherosclerosis.

Coronary Artery Disease 45

Coronary Artery Disease Atherosclerosis Laboratory Plaque 45

Journal of the American Heart Association

NOVEMBER 23, 2023

The expression of GPBAR1 in the human endothelium correlated with the expression of inflammatory biomarkers. Mice lackingFxrandGpbar1−/−/Fxr−/−display hypotension and aortic inflammation, along with altered intestinal permeability that deteriorates with age, and severe dysbiosis, along with dysregulated bile acid synthesis.

Aortic 40

Aortic Aneurysm Plaque Cholesterol 40

DAIC

JANUARY 23, 2024

Atherosclerotic cardiovascular disease (ASCVD), caused by plaque buildup in arterial walls, is one of the leading causes of disability and death worldwide.1,2 7 Research has shown inflammation plays a significant role in the development of atherosclerosis and ASCVD,8-10 and even the formation of plaque.11 Circulation.

Cardiovascular Disease 111

Cardiovascular Disease Heart Attack Heart attacks Coronary Artery Disease 111

Circulation: Cardiovascular Imaging

FEBRUARY 19, 2024

Circulation: Cardiovascular Imaging, Volume 17, Issue 2 , Page e016057, February 1, 2024. 18F-flourodeoxyglucose resting amygdalar uptake, an imaging biomarker of stress-related neural activity, coronary inflammation (fat attenuation index), and high-risk plaque characteristics were assessed by coronary computed tomography angiography.

Atherosclerosis 40

Atherosclerosis Plaque Coronary Artery Disease Biomarkers 40