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Circulating microRNAs as biomarkers of Chagas cardiomyopathy

Frontiers in Cardiovascular Medicine

Methods We carried out a case-control study to identify circulating miRNAs associated with CHCM. We performed a clinical, echocardiographic, and laboratory evaluation and profiled circulating miRNA in the serum samples. Results Differences between groups were observed in clinical variables and in the analysis of miRNAs.

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Abstract WP88: Association of renal biomarkers with fast progressor phenotype and related outcomes in anterior circulation large vessel occlusion stroke

Stroke Journal

Background:The effect of renal dysfunction on early infarct growth rate (IGR) in anterior circulation large vessel occlusion (ACLVO) stroke is not well studied. Renal dysfunction was assessed based on serum creatinine and estimated glomerular filtration rate (eGFR) on presenting laboratories. mL/min/1.73m2, p < 0.05).

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Roche's Lp(a) Gen.2 Molarity Assay Receives FDA Clearance

DAIC

By using molar units, laboratory professionals and clinicians know the Lp(a) measurements reflect the number of particles rather than any difference in the size of the particles. "We Circulation. Roche has an unrivaled ability to provide access to testing at scale and is committed to advancing innovation in preventive cardiology.

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Abstract 4146638: Comparative Assessment of hsCRP and Apolipoprotein B as ASCVD Risk Biomarkers

Circulation

Circulation, Volume 150, Issue Suppl_1 , Page A4146638-A4146638, November 12, 2024. Thus, levels above these thresholds for both apo B and hsCRP are associated with high ASCVD risk.Conclusion(s):The study demonstrates that apo B exhibits high discriminatory and diagnostic accuracy, making it a suitable ASCVD risk biomarker compared to hsCRP.

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Abstract 4148010: Evaluation of Echocardiography and Biomarkers for Prognostication of RV Failure in COVID-19 Patients Undergoing Extracorporeal Membrane Oxygenation (ECMO)

Circulation

Circulation, Volume 150, Issue Suppl_1 , Page A4148010-A4148010, November 12, 2024. Laboratory values including BNP, CRP, D-dimer, ferritin, fibrinogen, lactate and troponin were analyzed for correlation with echo findings.Results:TAPSE was significantly lower in deceased patients (1.9± 0.4cm vs 1.3±0.6 cm, P< 0.05).

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Coronary Artery Calcification: Current Concepts and Clinical Implications

Circulation

Circulation, Volume 149, Issue 3 , Page 251-266, January 16, 2024. It outlines the pathophysiology of CAC and reviews laboratory, histopathological, and genetic studies, as well as imaging findings, to characterize different types of calcification and to elucidate their implications.

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Abstract 4147019: Role of Fractional Excretion of Uric Acid as a Predictor of Cardio-renal Syndrome in Acute Decompensated Heart Failure Patients: An Observational Study

Circulation

Circulation, Volume 150, Issue Suppl_1 , Page A4147019-A4147019, November 12, 2024. Blood samples were collected, and various laboratory parameters were measured at day-1, day-3, and day-7. The fractional excretion of sodium (FeNa) and FeUa were calculated.Results:The mean age of participants was 52.32 ± 14.04