This site uses cookies to improve your experience. To help us insure we adhere to various privacy regulations, please select your country/region of residence. If you do not select a country, we will assume you are from the United States. Select your Cookie Settings or view our Privacy Policy and Terms of Use.
Cookie Settings
Cookies and similar technologies are used on this website for proper function of the website, for tracking performance analytics and for marketing purposes. We and some of our third-party providers may use cookie data for various purposes. Please review the cookie settings below and choose your preference.
Used for the proper function of the website
Used for monitoring website traffic and interactions
Cookie Settings
Cookies and similar technologies are used on this website for proper function of the website, for tracking performance analytics and for marketing purposes. We and some of our third-party providers may use cookie data for various purposes. Please review the cookie settings below and choose your preference.
Strictly Necessary: Used for the proper function of the website
Performance/Analytics: Used for monitoring website traffic and interactions
ObjectiveClinical practice currently faces a significant shortfall in specific biomarkers needed for diagnosing right ventricular (RV) remodeling in patients with pulmonary hypertension (PH). MiRNA sequencing analyses revealed 19 dif-miRNAs (12 upregulated and 7 downregulated) between the two groups.
Bioelectronic medicine scientists at The Feinstein Institutes for Medical Research used noninvasive, splenic focused ultrasound stimulation (sFUS) and found they can reduce inflammation and improve symptoms of pulmonary arterial hypertension (PAH). For years, Dr. Zanos has investigated bioelectronic medicine therapies to treat PAH.
Results of Tenax Therapeutics’ Phase 2 HELP study of levosimendan in patients with pulmonary hypertension (PH) with heart failure with preserved ejection fraction (HFpEF) demonstrated that I.V. Getty Images milla1cf Mon, 05/06/2024 - 10:48 May 6, 2024 — Tenax Therapeutics, Inc. ,
Circulation: Heart Failure, Ahead of Print. Background:Distinguishing hypertrophic cardiomyopathy (HCM) from other cardiomyopathies with left ventricular hypertrophy (LVH), such as hypertensive LVH, transthyretin amyloid cardiomyopathy (ATTR-CM), and aortic stenosis (AS), is sometimes challenging. and |log2(fold change)| >0.5
For example, blood pressure changes during exercise (EBP) can reveal a latent tendency toward future development of hypertension. At present, there is no reliable circulatingbiomarker—a protein or other molecule present in the blood stream—indicative of hypertension risk.
Circulation, Volume 151, Issue 10 , Page 716-732, March 11, 2025. Albuminuriaincreased urine albumin excretionis associated with cardiovascular mortality among patients with diabetes, hypertension, chronic kidney disease, or heart failure, as well as among adults with few cardiovascular risk factors.
Circulation, Volume 150, Issue Suppl_1 , Page A4144785-A4144785, November 12, 2024. Background:Acquired mitochondrial dysfunction is one of the characteristics of pulmonary arterial hypertension (PAH). Exploring potential biomarkers from mitochondrial perspective may be effective in the diagnosis and treatment of PAH.
Hypertension, Ahead of Print. Colocalization analyses were then used to investigate whether the circulating proteins and blood pressure traits shared causal genetic variants.
BackgroundChronic arterial hypertension restructures the vascular architecture of the brain, leading to a series of pathological responses that culminate in cerebral smallvessel disease. Journal of the American Heart Association, Ahead of Print. Microvessels were isolated for gene expression profiling and invitro pericyte expansion.
Circulation, Ahead of Print. BACKGROUND:Pulmonary hypertension, characterized by vascular remodeling, currently lacks curative therapeutic options. The dysfunction of pulmonary artery endothelial cells plays a pivotal role in the initiation and progression of pulmonary hypertension (PH).
Circulation: Heart Failure, Ahead of Print. BACKGROUND:Exercise-induced hypertension (EIH) is common in adults with coarctation of the aorta (COA), but there are limited data about hemodynamics and outcomes in such patients.
Circulation, Ahead of Print. BACKGROUND:Hypertension is a key risk factor for major adverse cardiovascular events but remains difficult to treat in many individuals. Dietary interventions are an effective approach to lower blood pressure (BP) but are not equally effective across all individuals. Intervention studies are warranted.
BackgroundPulmonary artery hypertension (PAH) is a fatal disease characterized by a complex pathogenesis. Exosomes containing microRNAs (miRs) have emerged as a novel biomarker. Transpulmonary exosomal miRs offer valuable insights into pulmonary circulation microenvironments.
Each year, the American Heart Association (AHA) gathers a Statistical Update, described as a major source for monitoring cardiovascular health, risk factors and disease in the United States and global population, and published annually in the AHA flagship journal Circulation. million, or 47% of adults are estimated to have hypertension.**
Circulation, Volume 150, Issue Suppl_1 , Page A4142484-A4142484, November 12, 2024. Background:Pulmonary arterial hypertension (PAH) is characterized by an elevation in pulmonary vascular resistance and arterial pressure, culminating in right ventricular failure and mortality.
While traditional vascular risk factors (eg, hypertension, dyslipidemia, tobacco use) account for 20% of the explained variance in carotid atherosclerosis, they remain a prominent focus for primary and secondary ischemic stroke prevention strategies. Stroke: Vascular and Interventional Neurology, Ahead of Print.
Circulation, Volume 150, Issue Suppl_1 , Page A4141170-A4141170, November 12, 2024. These findings suggest that 5-HTP could potentially be used as a biomarker for cardiovascular risk stratification. In cardiovascular research, serotonin has been implicated in modulating vascular tone, platelet aggregation, and myocardial function.
Circulation, Volume 150, Issue Suppl_1 , Page A4134796-A4134796, November 12, 2024. Early discharge of selected LR CP pts based on history, examination, ECG, and biomarker evaluation was safe and effective.Conclusion:This approach in selected LR pts has the potential to reduce unnecessary diagnostic testing and CPU LOS.
Circulation: Cardiovascular Quality and Outcomes, Volume 16, Issue 11 , Page e009609, November 1, 2023. Inverse probability of treatment weighting analysis showed no significant differences in the burden and control of hypertension (19.3% female; 13% non-Hispanic Black), 26.6% were current users. versus 18.8%,P=0.76; P=0.76; 79.8%
Moreover , the patient has ongoing symptoms and has an unexplained elevated troponin, so she is having an MI and the only question is whether it is type 1 or type 2 due to hypertension. The ESC states that patients with suspected ACS should go to the cath lab in <2 hours "regardless of ECG or biomarker evidence of MI!!" Mukherjee, D.,
The patient had no hypertension, no tachycardia, a normal hemoglobin, no drug use, no hypotension/shock, no murmur of aortic stenosis. The 4th, after the opening of the artery and release of troponin from the cardiac circulation, was 99.9 Acute myocardial injury: Is it myocardial infarction, or perhaps myocarditis? This includes: 1.
BackgroundThiazide diuretics are the second most frequently prescribed class of antihypertensives, but up to 50% of patients with hypertension have minimal antihypertensive response to thiazides. miRNAs with ≥2.5‐fold In the combined analysis of validation cohorts, let‐7g (odds ratio, 0.6 [95% 0.8]), miR‐142‐3p (odds ratio, 1.1 [95%
Circulation, Volume 150, Issue Suppl_1 , Page A4138593-A4138593, November 12, 2024. Multivariable Cox regression models were fitted to investigate additive prognostic differences.Results:The study population consisted mainly of blacks and major factors were hypertension, diabetes, mitral valve disease, and older age (p<0.0001).
In this study, we examined the relationship between ICH and CKD, as well as intracranial arterial calcification (IAC) as an intermediate biomarker. For each patient, eGFR (estimated glomerular filtration rate) along with age, sex, race, ethnicity, hypertension (HTN), diabetes (DM), heart disease, and hyperlipidemia were abstracted.
Part 1: Concepts, Indicator Variables, and Controversies The Annals of Thoracic Surgery January 2022 Arman Kilic Supplementing Existing Societal Risk Models for Surgical Aortic Valve Replacement With Machine Learning for Improved Prediction Journal of the American Heart Association November 2021 Jared Belle Strategies for Mechanical Right Ventricular (..)
Institutional Coronary Artery Bypass Case Volumes and Outcomes European Journal of Heart Failure October 2023 Makoto Mori 1 Robotic Mitral Valve Repair for Degenerative Mitral Regurgitation The Annals of Thoracic Surgery August 2023 Carlos Diaz-Castrillion 2 Volume-Failure to Rescue Relationship in Acute Type A Aortic Dissections: An Analysis of The (..)
Both reperfusion, as judged by the biomarker curve, and patency, as assessed by the angiogram, were correlated with the rapidity and depth of T wave inversion. Angiography usually reveals an absence of collateral circulation to the infarct zone. Circulation , 88 (3), 896904. link] [3] Oliva PB, Hammill SC, Edwards WD.
We organize all of the trending information in your field so you don't have to. Join thousands of users and stay up to date on the latest articles your peers are reading.
You know about us, now we want to get to know you!
Let's personalize your content
Let's get even more personalized
We recognize your account from another site in our network, please click 'Send Email' below to continue with verifying your account and setting a password.
Let's personalize your content