Journal of the American Heart Association

JANUARY 19, 2024

BackgroundAortic stenosis has pathophysiological similarities with atherosclerosis, including the deposition of cholesterol‐containing lipoproteins. The resulting cholesterol crystals activate the NLRP3 (NOD‐like receptor protein 3) inflammasome, leading to inflammation and cardiovascular diseases. per 100 person‐years,P=0.01).

Aortic valve 40

Aortic valve Cholesterol Aortic Stenosis 40

Stroke Journal

FEBRUARY 1, 2024

At 7-8 weeks after diabetes onset, control and diabetic rats were treated with ISMN/CZL for 4 weeks, then injected with cholesterol crystal ME and behavioral outcomes were monitored longitudinally for 16 weeks. Some of the biomarkers were unchanged (Table).

Biomarkers 40

Biomarkers Diabetes Cholesterol Stroke 40

Stroke Journal

FEBRUARY 1, 2024

Malnutrition is common in stroke patients and leads to worse outcomes. Body mass index (BMI) is a widely available marker of nutrition status, however studies on BMI and post-ICH outcomes are limited and have conflicting results. Future biomarker studies are needed to better understand this relationship. 5.94) groups.

Hemorrhage 40

Hemorrhage BMI Outcomes Coronary Artery Disease 40

Frontiers in Cardiovascular Medicine

MARCH 4, 2024

There are numerous effective medications for modifying CAD but new pharmacologic therapies require increasingly large and expensive cardiovascular outcome trials to assess their potential impact on MACE and to obtain regulatory approval. For many disease areas, nearly a half of drugs are approved by the U.S.

Plaque 59

Plaque Coronary Artery Disease Blood Pressure Cardiovascular Disease 59

All About Cardiovascular System and Disorders

DECEMBER 15, 2023

CLEAR Trial of Bempedoic Acid Bempedoic acid is an ATP citrate lyase inhibitor, acting upstream of HMGCoA reductase targeted by statins, and reduces LDL cholesterol levels. Thus the effect of bempedoic acid on cardiovascular events in those with lower LDL cholesterol levels and those on therapeutic doses of statins were not evaluated.

Cholesterol 52

Cholesterol Myocardial Infarction Cardiovascular Disease Diabetes 52

Circulation: Cardiovascular Quality & Outcomes

OCTOBER 20, 2023

Circulation: Cardiovascular Quality and Outcomes, Volume 16, Issue 11 , Page e009609, November 1, 2023. mg/dL,P=0.53), total cholesterol (191.2 mg/dL,P=0.53), total cholesterol (191.2 Further studies are needed to explore potential pathways between adverse cardiovascular disease outcomes and marijuana use. versus 3.0%,P=0.49),

Risk Factors 40

Risk Factors Cardiovascular Disease Cholesterol Biomarkers 40

DAIC

JANUARY 23, 2024

5 Over my career as a cardiovascular surgeon, as well as an immunologist, I have witnessed how current treatments for ASCVD have led to considerable improvements in outcomes, yet many patients remain vulnerable to life-threatening cardiac events.1,6 21 Luckily, each of these risks can be measured by simple blood tests.

Cardiovascular Disease 111

Cardiovascular Disease Heart Attack Heart attacks Coronary Artery Disease 111